Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Nicole Bégin"'
Autor:
Nicole Bégin-Heick, Monique Cadrin, Johanna Gaffield, Mary-Ellen Harper, Norma McFarlane-Anderson
Publikováno v:
Journal of Cellular Biochemistry. 62:334-341
The subcellular localization of the heterotrimeric G-proteins in hepatocytes in situ was compared to that in hepatocytes in primary culture. The ability of various ligands to activate adenylyl cyclase (AC) in membrane preparations was also investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd9f0e329f74cd39e27f4816e4a25dbc
https://doi.org/10.1002/(sici)1097-4644(199609)62:3<334::aid-jcb4>3.0.co
https://doi.org/10.1002/(sici)1097-4644(199609)62:3<334::aid-jcb4>3.0.co
Autor:
Nicole Bégin-Heick, Marsha A. Black
Publikováno v:
Journal of Cellular Biochemistry. 58:455-463
Stromal vascular cells from epididymal fat pads of lean and obese mice were cultured in a medium (alpha-MEM) containing fetal bovine serum (FBS) and cell replication followed for 11 days. In both types of cells, confluence occurred at 4-5 days, after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50b72eda9d1e073823857889dce95fc
https://doi.org/10.1002/jcb.240580408
https://doi.org/10.1002/jcb.240580408
Autor:
Nicole Bégin-Heick
Publikováno v:
Journal of Cellular Biochemistry. 58:464-473
Lipolysis and adenylyl cyclase (AC) activation in response to beta-adrenergic agents are abnormally low in white epididymal adipose tissue (WAT) of the ob/ob mouse. The abundance of G-proteins (Gs alpha and Gi alpha) linked to AC is also abnormally l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92fd29f5c42229b9221222c45cb03e0
https://doi.org/10.1002/jcb.240580409
https://doi.org/10.1002/jcb.240580409
Publikováno v:
Biochemistry and Cell Biology. 71:518-521
The HGFu and Ob17 cell lines, derived from adipose tissue of lean (+/?) and ob/ob mice, respectively, express several G-protein peptides. Investigation of the expression and subcellular localization of the Giα3 subunit showed that this peptide is as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::369fd8f0618c22f689a1352cb98b0051
https://doi.org/10.1139/o93-074
https://doi.org/10.1139/o93-074
Publikováno v:
Biochemical Journal. 282:15-23
G-protein levels were assessed in liver and brain membranes of lean and obese mice. ADP-ribosylation and immunodetection studies revealed a decrease in the abundance of Gs and Gi alpha-subunits in the liver membranes of obese mice compared with lean
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0ef42a61801419e07e0038aaf42716
https://doi.org/10.1042/bj2820015
https://doi.org/10.1042/bj2820015
Autor:
Nicole Bégin-Heick
Publikováno v:
Biochemical Journal. 268:83-89
The abundance of the alpha and beta subunits of the GTP-binding proteins (G-proteins) that transduce hormonal messages to adenylate cyclase was assessed in adipocyte membranes from lean (+/+) and obese (ob/ob) mice, using ADP-ribosylation with bacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047a9c1249c8895b20908d7e0fb91470
https://doi.org/10.1042/bj2680083
https://doi.org/10.1042/bj2680083
Publikováno v:
Biochemistry and Cell Biology. 68:243-248
The present study was undertaken to determine whether factors that affect K+ permeability produce differences in insulin secretion in the islets of obese versus lean mice. At basal glucose (3 mM), the obese islets secreted more insulin for a given in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac71688aa4a7281123733759a65c07f
https://doi.org/10.1139/o90-033
https://doi.org/10.1139/o90-033
Publikováno v:
Journal of cellular biochemistry. 65(2)
The subcellular localization of G5 alpha, Gi alpha 1&2, Gi alpha 3, and G beta was studied in primary-cultured undifferentiated and differentiated, lipid replete, adipose cells. The results show a distinct distribution for each of these G-proteins an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4564a0ba938d55df37e64774f1304b6
https://pubmed.ncbi.nlm.nih.gov/9136083
https://pubmed.ncbi.nlm.nih.gov/9136083
Autor:
Nicole Bégin-Heick
Publikováno v:
Biochemistry and cell biology = Biochimie et biologie cellulaire. 74(5)
The metabolic response of adipose tissue to stimuli leading to lipid mobilization is important in determining the direction of metabolism and the degree to which adipose tissue can store lipids and release fatty acids in times of need. The lipolytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f1796e43e493e4f2455495f8f7c514c
https://pubmed.ncbi.nlm.nih.gov/9018368
https://pubmed.ncbi.nlm.nih.gov/9018368
Autor:
Jean-Louis Schwartz, Marsha A. Black, James F. Whitfield, Nicole Bégin-Heick, Geoffrey A.R. Mealing
Publikováno v:
Cellular signalling. 6(8)
Glucose-induced insuline release, glucose-induced rises in intracellular free Ca 2+ concentration ([Ca 2+ ] i ), and voltage-dependent Ca 2+ channel activity were assessed in monolayer cultures of β-vells 3–5 day-old rats. The glucose-stimulated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f78f784182a4a3d1c9cbd0eee4bc0b
https://pubmed.ncbi.nlm.nih.gov/7718409
https://pubmed.ncbi.nlm.nih.gov/7718409