Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nicole Andenmatten"'
Autor:
Mohammed H. Cherkaoui‐Rbati, Nicole Andenmatten, Lydia Burgert, Oluwaseun F. Egbelowo, Rolf Fendel, Chiara Fornari, Michael Gabel, John Ward, Jörg J. Möhrle, Nathalie Gobeau
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 1, Pp 50-61 (2023)
Abstract Chemoprophylactics are a vital tool in the fight against malaria. They can be used to protect populations at risk, such as children younger than the age of 5 in areas of seasonal malaria transmission or pregnant women. Currently approved che
Externí odkaz:
https://doaj.org/article/91245b38753741cfa2057e092803c40e
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-5 (2019)
Abstract Background Drug efficacy against kelch 13 mutant malaria parasites can be determined in vitro with the ring-stage survival assay (RSA). The conventional assay protocol reflects the exposure profile of dihydroartemisinin. Methods Taking into
Externí odkaz:
https://doaj.org/article/4a4c425c4414479485ec6851ec4d9c8a
Autor:
Amelia E. Hanron, Zachary P. Billman, Annette M. Seilie, Tayla M. Olsen, Matthew Fishbaugher, Ming Chang, Thomas Rueckle, Nicole Andenmatten, Bryan Greenhouse, Emmanuel Arinaitwe, John Rek, Smita Das, Gonzalo J. Domingo, Kelly Shipman, Stefan H. Kappe, James G. Kublin, Sean C. Murphy
Publikováno v:
Malaria Journal, Vol 16, Iss 1, Pp 1-13 (2017)
Abstract Background Plasmodium gametocytes are sexual stages transmitted to female Anopheles mosquitoes. While Plasmodium parasites can be differentiated microscopically on Giemsa-stained blood smears, molecular methods are increasingly used because
Externí odkaz:
https://doaj.org/article/f7424a129d9c40aba01268d6dd1055fe
Autor:
Daniel Bargieri, Vanessa Lagal, Nicole Andenmatten, Isabelle Tardieux, Markus Meissner, Robert Ménard
Publikováno v:
PLoS Pathogens, Vol 10, Iss 9, p e1004273 (2014)
Externí odkaz:
https://doaj.org/article/e2821190c3434a93884a8ebf69641705
Autor:
Saskia Egarter, Nicole Andenmatten, Allison J Jackson, Jamie A Whitelaw, Gurman Pall, Jennifer Ann Black, David J P Ferguson, Isabelle Tardieux, Alex Mogilner, Markus Meissner
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91819 (2014)
Apicomplexan parasites are thought to actively invade the host cell by gliding motility. This movement is powered by the parasite's own actomyosin system, and depends on the regulated polymerisation and depolymerisation of actin to generate the force
Externí odkaz:
https://doaj.org/article/44bd822922444a7e9fa7588e7ecc3280
Autor:
Claudia Demarta-Gatsi, Nicole Andenmatten, María-Belén Jiménez-Díaz, Nathalie Gobeau, Mohammed H. Cherkaoui-Rabti, Aline Fuchs, Pablo Díaz, Sandra Berja, Rebeca Sánchez, Hazel Gómez, Estíbaliz Ruiz, Paula Sainz, Eider Salazar, Rodrigo Gil-Merino, Luis Manuel Mendoza, Cristina Eguizabal, Didier Leroy, Joerg J. Moehrle, Belen Tornesi, Iñigo Angulo-Barturen
Publikováno v:
Antimicrobial Agents and Chemotherapy.
The development of new combinations of antimalarial drugs is urgently needed to prevent the spread of parasites resistant to drugs in clinical use and contribute to the control and eradication of malaria. In this work, we evaluated a standardized hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53c221c5967724cbd728d2d32168ef89
https://doi.org/10.1128/aac.01574-22
https://doi.org/10.1128/aac.01574-22
Autor:
Mohammed H. Cherkaoui‐Rbati, Nicole Andenmatten, Lydia Burgert, Oluwaseun F. Egbelowo, Rolf Fendel, Chiara Fornari, Michael Gabel, John Ward, Jörg J. Möhrle, Nathalie Gobeau
Publikováno v:
CPT: pharmacometricssystems pharmacologyREFERENCES.
Chemoprophylactics are a vital tool in the fight against malaria. They can be used to protect populations at risk, such as children younger than the age of 5 in areas of seasonal malaria transmission or pregnant women. Currently approved chemoprophyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aafa92052639bed8fff16eeb025cd9c
https://pubmed.ncbi.nlm.nih.gov/36412499
https://pubmed.ncbi.nlm.nih.gov/36412499
Autor:
Kevin Gillespie, Nicole Andenmatten, Youyi Fong, Stefan H. I. Kappe, Holly Janes, Ryan L. Jensen, Nicola Kerr, Annette M. Seilie, Sean R. Marcsisin, Jörg J. Möhrle, Amelia E. Hanron, Tracie VonGoedert, Sue Ferguson, Kelly J. Shipman, Elizabeth R. Duke, James G. Kublin, Stephan Duparc, Laurie Rinn, Thomas Rueckle, Emma Fritzen, Matthew Fishbaugher, Ming Chang, Stephan Chalon, Jason C. Sousa, Sean C. Murphy
Publikováno v:
The Journal of Infectious Diseases. 217:693-702
Background DSM265 is a selective inhibitor of Plasmodium dihydroorotate dehydrogenase that fully protected against controlled human malarial infection (CHMI) by direct venous inoculation of Plasmodium falciparum sporozoites when administered 1 day be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6918a2614f5f9f725784af4dc94b7f47
https://doi.org/10.1093/infdis/jix613
https://doi.org/10.1093/infdis/jix613
Autor:
Monica Longo, Jon Rhodes, Thomas Rückle, Joseph Kinney, Robert L. Clark, Don K. Walker, Anna Christine Huber, Tammye L. Edwards, Timothy N. C. Wells, Nicole Andenmatten, Sally Clode
Publikováno v:
Birth Defects Research. 110:553-578
Background Combination medicines including an artemisinin are the mainstay of antimalarial therapy. Artemisinins are potent embryotoxicants in animal species due to their trioxane moiety. Methods As part of its development, the new synthetic trioxola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a30e1a21f41734b8e019448431cd69
https://doi.org/10.1002/bdr2.1170
https://doi.org/10.1002/bdr2.1170
Publikováno v:
Malaria Journal
Malaria Journal, Vol 18, Iss 1, Pp 1-5 (2019)
Malaria Journal, Vol 18, Iss 1, Pp 1-5 (2019)
Background Drug efficacy against kelch 13 mutant malaria parasites can be determined in vitro with the ring-stage survival assay (RSA). The conventional assay protocol reflects the exposure profile of dihydroartemisinin. Methods Taking into account t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489fd958a5409440b1b6413842fd6b1b
https://pubmed.ncbi.nlm.nih.gov/31849323
https://pubmed.ncbi.nlm.nih.gov/31849323