Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nicole A. Teaney"'
Autor:
Wardiya Afshar-Saber, Cidi Chen, Nicole A. Teaney, Kristina Kim, Ziqin Yang, Federico M. Gasparoli, Darius Ebrahimi-Fakhari, Elizabeth D. Buttermore, Ivy Pin-Fang Chen, Phillip L. Pearl, Mustafa Sahin
Publikováno v:
Stem Cell Research, Vol 77, Iss , Pp 103424- (2024)
Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD) is an ultra-rare autosomal recessive neurometabolic disorder caused by ALDH5A1 mutations presenting with autism and epilepsy. Here, we report the generation and characterization of human induced
Externí odkaz:
https://doaj.org/article/3f29105d885d41a69adcd8bd9288c39b
Autor:
Wardiya Afshar-Saber, Nicole A. Teaney, Kellen D. Winden, Hellen Jumo, Xutong Shi, Gabrielle McGinty, Jed Hubbs, Cidi Chen, Itay Tokatly Latzer, Federico Gasparoli, Darius Ebrahimi-Fakhari, Elizabeth D. Buttermore, Jean-Baptiste Roullet, Phillip L. Pearl, Mustafa Sahin
Publikováno v:
Neurobiology of Disease, Vol 190, Iss , Pp 106386- (2024)
Succinic semialdehyde dehydrogenase deficiency (SSADHD) is a neurometabolic disorder caused by ALDH5A1 mutations presenting with autism and epilepsy. SSADHD leads to impaired GABA metabolism and results in accumulation of GABA and γ-hydroxybutyrate
Externí odkaz:
https://doaj.org/article/6afdfd05e9854926bfb6dac05d7d20fc
Autor:
Nicole A. Teaney, Nicole E. Cyr
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Forkhead box O (FoxO) proteins are transcription factors that mediate many aspects of physiology and thus have been targeted as therapeutics for several diseases including metabolic disorders such as type 2 diabetes mellitus (T2D). The role of FoxO1
Externí odkaz:
https://doaj.org/article/901f68456ed449c69ce3382f4e95dd2f
Autor:
Kellen D. Winden, Truc T. Pham, Nicole A. Teaney, Juan Ruiz, Ryan Chen, Cidi Chen, Mustafa Sahin
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112838- (2023)
Summary: Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder, but new therapies have been impeded by a lack of understanding of the pathological mechanisms. Tuberous sclerosis complex (TSC) and fragile X syndrome are asso
Externí odkaz:
https://doaj.org/article/70a2b2c8add248b4a5c39d56149e00ec
Autor:
Nicole A Teaney, Nicole E Cyr
Publikováno v:
Journal of the Endocrine Society. 5:A56-A57
The nutrient-sensor protein Sirtuin 1 (Sirt1; silent mating type information regulation 2 homolog 1) has been shown to have significant and opposing effects on insulin resistance, leptin resistance, and body weight in the periphery and the brain. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59c678b184b8362e442079ee005b7741
https://doi.org/10.1210/jendso/bvab048.114
https://doi.org/10.1210/jendso/bvab048.114