Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nicole A. Kirven"'
Autor:
Alexandra Indeglia, Jessica C. Leung, Sven A. Miller, Julia I-Ju Leu, James F. Dougherty, Nicole L. Clarke, Nicole A. Kirven, Chunlei Shao, Lei Ke, Scott Lovell, Thibaut Barnoud, David Y. Lu, Cindy Lin, Toshitha Kannan, Kevin P. Battaile, Tyler Hong Loong. Yang, Isabela Batista Oliva, Daniel T. Claiborne, Peter Vogel, Lijun Liu, Qin Liu, Yulia Nefedova, Joel Cassel, Noam Auslander, Andrew V. Kossenkov, John Karanicolas, Maureen E. Murphy
Publikováno v:
Cancer Discovery.
TP53 is the most frequently mutated gene in cancer, yet key target genes for p53-mediated tumor suppression remain unidentified. Here, we characterize a rare, African-specific, germline variant of TP53 in the DNA binding domain, Tyr107His (Y107H). NM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fa221f30ff7da8667ad8c17d4a66bc8
https://doi.org/10.1158/2159-8290.cd-22-1315
https://doi.org/10.1158/2159-8290.cd-22-1315
Autor:
Jessica C. Leung, Julia I-Ju Leu, Alexandra Indeglia, Toshitha Kannan, Nicole L. Clarke, Nicole A. Kirven, Harsh Dweep, David Garlick, Thibaut Barnoud, Andrew V. Kossenkov, Donna L. George, Maureen E. Murphy
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Missense mutations that inactivate p53 occur commonly in cancer, and germline mutations in TP53 cause Li Fraumeni syndrome, which is associated with early-onset cancer. In addition, there are over two hundred germline missense variants of p53 that re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab28ae4390fa5244828ea13e1e18b87d
https://doi.org/10.1073/pnas.2212940120
https://doi.org/10.1073/pnas.2212940120
Autor:
Weili Ma, Adi Naryana Reddy Poli, Joseph M. Salvino, Jessica C. Leung, Qing Chen, Julia I-Ju Leu, Maureen E. Murphy, Thibaut Barnoud, Donna L. George, Nicole A. Kirven, Andrew V. Kossenkov, Qin Liu, Ashani T. Weeraratna, Joshua L.D. Parris
Publikováno v:
Cancer Res Commun
NRAS-mutant melanoma is currently a challenge to treat. This is due to an absence of inhibitors directed against mutant NRAS, along with adaptive and acquired resistance of this tumor type to inhibitors in the MAPK pathway. Inhibitors to MEK have sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3558aaf6fc5b270d999686cbe5ccd7a
https://doi.org/10.1158/2767-9764.crc-21-0033
https://doi.org/10.1158/2767-9764.crc-21-0033
Autor:
Catherine M. Mageeney, Alecia B. Rokes, Alexa A. Alhout, Nicholas C. Kahler, Caitlin M. Zuilkoski, Brianna Gipson, Krishna Patel, Margaret A. Kenna, Russell Caratenuto, Jamie B. Korenberg, Wascar A. Ramirez, Matthew S. Grapel, Maaz M. Haleem, Lauren N. McKinley, Matthew J. Thoonkuzhy, Katherine R. Volpe, Cassidy L. Drost, Kevin D. Zhang, Caitlin E. Murphy, Grace O. Ciabattoni, Hamidu T. Mohammed, Longhui Gao, Lauren M. Pyfer, Lauren A. Vargas, Julia C. Melehani, Brooke P. Lichak, Croldy A. Veliz, Nicole Capogna, Francis F. Akoto, Vassie C. Ware, Matthew C. West, Nicole A. Kirven, Netta Cudkevich, Rachel H. Swope, Kourtney R. Mendello, Dylan Z. Faltine-Gonzalez, Lee H. Graham, Ryan A. Seth, Nicolas J. DesGranges, Julia R. Reisner
Publikováno v:
Microbiology Resource Announcements
The annotation of six cluster N Mycobacterium smegmatis phages (Kevin1, Nenae, Parmesanjohn, ShrimpFriedEgg, Smurph, and SpongeBob) reveals regions of genomic diversity, particularly within the central region of the genome. The genome of Kevin1 inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9ed717a7bd4e40266cbdded62abe6d
http://europepmc.org/articles/PMC6544188
http://europepmc.org/articles/PMC6544188