Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Nicole A. Haverland"'
Autor:
Anthony W. Goering, Ryan A. McClure, James R. Doroghazi, Jessica C. Albright, Nicole A. Haverland, Yongbo Zhang, Kou-San Ju, Regan J. Thomson, William W. Metcalf, Neil L. Kelleher
Publikováno v:
ACS Central Science, Vol 2, Iss 2, Pp 99-108 (2016)
Externí odkaz:
https://doaj.org/article/deb6678d807b4d9ca6d6bdea3528e870
Autor:
Neil L. Kelleher, Kristina Srzentić, Owen S. Skinner, Nicole A. Haverland, Luca Fornelli, Luis H. F. Do Vale, Henrique S. Seckler, Philip D. Compton, Rafael D. Melani, Luis F. Schachner, Peter F. Doubleday
Publikováno v:
Nature chemical biology
Protein complexes exhibit great diversity in protein membership, post-translational modifications and noncovalent cofactors, enabling them to function as the actuators of many important biological processes. The exposition of these molecular features
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467e175041b99ce05efa5847ee7f9b6a
https://doi.org/10.1038/nchembio.2515
https://doi.org/10.1038/nchembio.2515
Autor:
Ryan T. Fellers, Bryan P. Early, Areeba Tariq, Richard D. LeDuc, Nicole A. Haverland, Philip D. Compton, Neil L. Kelleher, Luca Fornelli, Owen S. Skinner
Publikováno v:
Journal of the American Society for Mass Spectrometry. 28:1203-1215
Fragmentation of intact proteins in the gas phase is influenced by amino acid composition, the mass and charge of precursor ions, higher order structure, and the dissociation technique used. The likelihood of fragmentation occurring between a pair of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab4c08b76cb62031c8af12ec557bb24
https://doi.org/10.1007/s13361-017-1635-x
https://doi.org/10.1007/s13361-017-1635-x
Autor:
Nicole A. Haverland, Neil L. Kelleher, James R. Doroghazi, Kou San Ju, Anthony W. Goering, Jessica C. Albright, Yongbo Zhang, Ryan A. McClure, William W. Metcalf, Regan J. Thomson
Publikováno v:
ACS Central Science, Vol 2, Iss 2, Pp 99-108 (2016)
ACS Central Science
ACS Central Science
For more than half a century the pharmaceutical industry has sifted through natural products produced by microbes, uncovering new scaffolds and fashioning them into a broad range of vital drugs. We sought a strategy to reinvigorate the discovery of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6861674c0222a8e65309fa43c7a3865a
https://doi.org/10.1021/acscentsci.5b00331
https://doi.org/10.1021/acscentsci.5b00331
Autor:
Nicole A. Haverland, Melinda Wojtkiewicz, Pawel Ciborowski, Jason DeBoer, Yan Li, Emma Harwood, Michael Belshan, Joseph W. George, Emily Leshen
Viral pathogenesis results from changes in host cells due to virus usurpation of the host cell and the innate cellular responses to thwart infection. We measured global changes in protein expression and localization in HIV-1 infected T-cells using su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3921f6de8ca1418a2a347b462b7f9993
https://europepmc.org/articles/PMC5836514/
https://europepmc.org/articles/PMC5836514/
Publikováno v:
Journal of Neuroimmunology. 278:162-173
Neurodegeneration after traumatic brain injury is facilitated by innate and adaptive immunity and can be harnessed to affect brain repair. In mice subjected to controlled cortical impact (CCI), we show that treatment with granulocyte macrophage colon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aeda2b01770d3c5f310a0e251762232
https://doi.org/10.1016/j.jneuroim.2014.11.002
https://doi.org/10.1016/j.jneuroim.2014.11.002
Autor:
Owen S. Skinner, Peter F. Doubleday, Luca Fornelli, Neil L. Kelleher, Henrique S. Seckler, Luis F. Schachner, Philip D. Compton, Nicole A. Haverland
Publikováno v:
The FASEB Journal. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32b2c6770aa354790fe4ebc3fec1ab2f
https://doi.org/10.1096/fasebj.31.1_supplement.760.2
https://doi.org/10.1096/fasebj.31.1_supplement.760.2
Autor:
Christian J. Madson, Pawel Ciborowski, Michael Belshan, Nicole A. Haverland, Teena Jagadish, Jason DeBoer
Publikováno v:
Virology. :409-420
Virus infection of a cell involves the appropriation of host factors and the innate defensive response of the cell. The identification of proteins critical for virus replication may lead to the development of novel, cell-based inhibitors. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5bade3a32cde4f7e93f1246a74d826
Autor:
Pawel Ciborowski, Nicole A. Haverland, Teena Jagadish, Cameron J. Schweitzer, Michael Belshan
Publikováno v:
Journal of Proteome Research. 12:559-572
After entry into the cell, the early steps of the human immunodeficiency virus type 1 (HIV-1) replication cycle are mediated by two functionally distinct nucleoprotein complexes, the reverse transcription complex (RTC) and preintegration complex (PIC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09431fabf50c33d4ecaefcc4f9d8b30d
https://doi.org/10.1021/pr300869h
https://doi.org/10.1021/pr300869h
Publikováno v:
Methods in Molecular Biology ISBN: 9781493930456
Proteomics holds great promise for uncovering disease-related markers and mechanisms in human disorders. Recent advances have led to efficient, sensitive, and reproducible methods to quantitate the proteome in biological samples. Here we describe the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fd5807d9c4c4153ba9b35397d00c060
https://doi.org/10.1007/978-1-4939-3046-3_20
https://doi.org/10.1007/978-1-4939-3046-3_20