Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Nicole A. Crowley"'
Autor:
Avery R. Sicher, Andrea Liss, Valentina Vozella, Paige Marsland, Laurel R. Seemiller, Matthew Springer, William D. Starnes, Keith R. Griffith, Grace C. Smith, Amy Astefanous, Terrence Deak, Marisa Roberto, Florence P. Varodayan, Nicole A. Crowley
Publikováno v:
Addiction Neuroscience, Vol 12, Iss , Pp 100171- (2024)
Adolescence is a period of increased risk taking, including increased alcohol and drug use. Multiple clinical studies report a positive relationship between adolescent alcohol consumption and risk of developing an alcohol use disorder (AUD) in adulth
Externí odkaz:
https://doaj.org/article/49af5c155eb34ae49af2eede2ae66b08
Autor:
Laurel R. Seemiller, Julio Flores-Cuadra, Keith R. Griffith, Grace C. Smith, Nicole A. Crowley
Publikováno v:
Neurobiology of Stress, Vol 29, Iss , Pp 100605- (2024)
Alzheimer's Disease and related dementias (ADRD) are an increasing threat to global health initiatives. Efforts to prevent the development of ADRD require understanding behaviors that increase and decrease risk of neurodegeneration and cognitive decl
Externí odkaz:
https://doaj.org/article/43a5e825c5644f3baa23628192eac7df
Autor:
Dakota F. Brockway, Keith R. Griffith, Chloe M. Aloimonos, Thomas T. Clarity, J. Brody Moyer, Grace C. Smith, Nigel C. Dao, Md Shakhawat Hossain, Patrick J. Drew, Joshua A. Gordon, David A. Kupferschmidt, Nicole A. Crowley
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112976- (2023)
Summary: We sought to characterize the unique role of somatostatin (SST) in the prelimbic (PL) cortex in mice. We performed slice electrophysiology in pyramidal and GABAergic neurons to characterize the pharmacological mechanism of SST signaling and
Externí odkaz:
https://doaj.org/article/6d6c0587838643a4b9fa5f7bc88a9bac
Autor:
Malini Suresh Nair, Nigel C. Dao, Daniela Lopez Melean, Keith R. Griffith, W. David Starnes, J. Brody Moyer, Avery R. Sicher, Dakota F. Brockway, Kathleen D. Meeks, Nicole A. Crowley
Publikováno v:
Brain Research Bulletin, Vol 186, Iss , Pp 38-46 (2022)
Alcohol use disorder (AUD) is characterized by alcohol use coupled with chronic relapse and involves brain regions including the bed nucleus of the stria terminalis (BNST). Here, we explore whether a subpopulation of BNST neurons, somatostatin (SST)
Externí odkaz:
https://doaj.org/article/c4aa9d521b2741089088b22458199128
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Human adolescence is a period of development characterized by wide ranging emotions and behavioral risk taking, including binge drinking (Konrad et al., 2013). These behavioral manifestations of adolescence are complemented by growth in the neuroarch
Externí odkaz:
https://doaj.org/article/a5ecbe4787094cdc8c57aec8e9b0d532
Autor:
Dakota F. Brockway, Nicole A. Crowley
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
Recent advancements in technology have enabled researchers to probe the brain with the greater region, cell, and receptor specificity. These developments have allowed for a more thorough understanding of how regulation of the neurophysiology within a
Externí odkaz:
https://doaj.org/article/2c2df92fa07f4cb89010d3171ae52247
Autor:
Nigel C. Dao, Malini Suresh Nair, Sarah N. Magee, J. Brody Moyer, Veronica Sendao, Dakota F. Brockway, Nicole A. Crowley
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
Forced abstinence (FA) from alcohol has been shown to produce a variety of anxiety- and depression-like symptoms in animal models. Somatostatin (SST) neurons, a subtype of GABAergic neurons found throughout the brain, are a novel neural target with p
Externí odkaz:
https://doaj.org/article/1cbcd53b708d43639d7355019f7205b7
Autor:
Nicole A. Crowley, Daniel W. Bloodgood, J. Andrew Hardaway, Alexis M. Kendra, Jordan G. McCall, Ream Al-Hasani, Nora M. McCall, Waylin Yu, Zachary L. Schools, Michael J. Krashes, Bradford B. Lowell, Jennifer L. Whistler, Michael R. Bruchas, Thomas L. Kash
Publikováno v:
Cell Reports, Vol 14, Iss 12, Pp 2774-2783 (2016)
Kappa opioid receptors (KORs) are involved in a variety of aversive behavioral states, including anxiety. To date, a circuit-based mechanism for KOR-driven anxiety has not been described. Here, we show that activation of KORs inhibits glutamate relea
Externí odkaz:
https://doaj.org/article/1e77c85eb79e463d9b87426cfc36833a
Autor:
Avery R. Sicher, William D. Starnes, Keith R. Griffith, Nigel C. Dao, Grace C. Smith, Dakota F. Brockway, Nicole A. Crowley
Publikováno v:
Neuropharmacology. 234:109561
Adolescent drug consumption has increased risks to the individual compared to consumption in adulthood, due to the likelihood of long-term and permanent behavioral and neurological adaptations. However, little is known about how adolescent alcohol co
Publikováno v:
Neuropsychopharmacology. 46:1906-1917
Somatostatin (SST) neurons have been implicated in a variety of neuropsychiatric disorders such as depression and anxiety, but their role in substance use disorders, including alcohol use disorder (AUD), is not fully characterized. Here, we found tha