Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nicole A Najor"'
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31575 (2012)
In Saccharomyces cerevisiae, the G1 cyclin/cyclin-dependent kinase (CDK) complexes Cln1,-2,-3/Cdk1 promote S phase entry during the mitotic cell cycle but do not function during meiosis. It has been proposed that the meiosis-specific protein kinase I
Externí odkaz:
https://doaj.org/article/8f30eba503e341bfb6a9892e66eace1a
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 12, Pp 3869-3881 (2016)
In the budding yeast Saccharomyces cerevisiae, unnatural stabilization of the cyclin-dependent kinase inhibitor Sic1 during meiosis can trigger extra rounds of DNA replication. When programmed DNA double-strand breaks (DSBs) are generated but not rep
Externí odkaz:
https://doaj.org/article/16397ed5ad70482a94a752837add797b
Autor:
Nicole Ann Najor, Gillian Nicole Fitz, Jennifer Leigh Koetsier, Lisa Marie Godsel, Lauren Veronica Albrecht, Robert Harmon, Kathleen Janee Green
Publikováno v:
eLife, Vol 6 (2017)
Cell junctions are scaffolds that integrate mechanical and chemical signaling. We previously showed that a desmosomal cadherin promotes keratinocyte differentiation in an adhesion-independent manner by dampening Epidermal Growth Factor Receptor (EGFR
Externí odkaz:
https://doaj.org/article/d9d557bfffff497fa0f5ebd3d53c9bed
Autor:
Constadina Arvanitis, Eli Sprecher, Kathleen J. Green, Jennifer L. Koetsier, Nicole A. Najor, Eran Cohen-Barak, Lisa M. Godsel, Marihan Hegazy
Publikováno v:
Curr Protoc Cell Biol
Biochemical methods can reveal stable protein-protein interactions occurring within cells, but the ability to observe transient events and to visualize the subcellular localization of protein-protein interactions in cells and tissues in situ provides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d510c7969dcca4971bcbfda48862773f
https://pubmed.ncbi.nlm.nih.gov/33044803
https://pubmed.ncbi.nlm.nih.gov/33044803
Autor:
Nicole A. Najor
Publikováno v:
Annual Review of Pathology: Mechanisms of Disease. 13:51-70
Tissue integrity is crucial for maintaining the homeostasis of living organisms. Abnormalities that affect sites of cell-cell contact can cause a variety of debilitating disorders. The desmosome is an essential cell-cell junctional protein complex in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e457d0dc5b048cc86b931f9900bf21
https://doi.org/10.1146/annurev-pathol-020117-044030
https://doi.org/10.1146/annurev-pathol-020117-044030
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 6, Iss 12, Pp 3869-3881 (2016)
G3: Genes, Genomes, Genetics, Vol 6, Iss 12, Pp 3869-3881 (2016)
In the budding yeast Saccharomyces cerevisiae, unnatural stabilization of the cyclin-dependent kinase inhibitor Sic1 during meiosis can trigger extra rounds of DNA replication. When programmed DNA double-strand breaks (DSBs) are generated but not rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4ea3b70a371ced817f0b1f07930337
http://europepmc.org/articles/PMC5144958
http://europepmc.org/articles/PMC5144958
Autor:
Jennifer L. Koetsier, Lauren V. Albrecht, Kathleen J. Green, Robert M. Harmon, Gillian Nicole Fitz, L. Godsel, Nicole A. Najor
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Cell junctions are scaffolds that integrate mechanical and chemical signaling. We previously showed that a desmosomal cadherin promotes keratinocyte differentiation in an adhesion-independent manner by dampening Epidermal Growth Factor Receptor (EGFR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721b2cf48e2f74f347fc52c042aa36b8
http://europepmc.org/articles/PMC5663478
http://europepmc.org/articles/PMC5663478
Autor:
Nicole A. Najor, Adi D. Dubash, Jennifer L. Koetsier, Kathleen J. Green, Evangeline V. Amargo, Robert M. Harmon
Publikováno v:
The Journal of Cell Biology
The GEF Bcr promotes RhoA-dependent actin remodeling and MAL/SRF signaling in keratinocytes, which in turn promotes differentiation via regulation of desmoglein-1 expression.
Although much is known about signaling factors downstream of Rho GTPas
Although much is known about signaling factors downstream of Rho GTPas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd9f80514a32ce541ab0a302480a9c1
https://doi.org/10.1083/jcb.201304133
https://doi.org/10.1083/jcb.201304133
Autor:
Noam Erez, Sarah Edie, Jouni Uitto, Akemi Ishida-Yamamoto, Stephen A. Murray, N. Malchin, Meital Grafi-Cohen, Gilad Fainberg, Kathleen J. Green, Benjamin Meilik, Lauren V. Albrecht, Ofer Sarig, Tomer Goldsmith, Eli Sprecher, Leonard D. Shultz, Qiaoli Li, R. Bochner, Tova Rogers, Lisa M. Burzenski, Alan D. Irvine, Dan Vodo, Ilan Goldberg, Emily Warshauer, Liat Samuelov, Nicole A. Najor
Publikováno v:
Experimental dermatology. 26(5)
SVEP1 is a recently identified multi-domain cell adhesion protein, homologous to the mouse polydom protein, which has been shown to mediate cell-cell adhesion in an integrin dependent-manner in osteogenic cells. In the present study, we characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491d9bfa3edc4b5614666f4c26e5fe45
https://pubmed.ncbi.nlm.nih.gov/27892606
https://pubmed.ncbi.nlm.nih.gov/27892606