Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Nicole A M Dekker"'
Autor:
Anoek L I van Leeuwen, Elise Beijer, Roselique Ibelings, Nicole A M Dekker, Marjolein R A van der Steen, Joris J T H Roelofs, Matijs van Meurs, Grietje Molema, Charissa E van den Brom
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0293673 (2023)
BackgroundThe endothelial angiopoietin/Tie2 system is an important regulator of endothelial permeability and targeting Tie2 reduces hemorrhagic shock-induced organ edema in males. However, sexual dimorphism of the endothelium has not been taken into
Externí odkaz:
https://doaj.org/article/2ac4c83dd5644c58a18fa8b1e6658a17
Autor:
Nicole A. M. Dekker, Anoek L. I. van Leeuwen, Matijs van Meurs, Jill Moser, Jeannette E. Pankras, Nicole N. van der Wel, Hans W. Niessen, Marc G. Vervloet, Alexander B. A. Vonk, Peter L. Hordijk, Christa Boer, Charissa E. van den Brom
Publikováno v:
Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-19 (2021)
Abstract Background Acute kidney injury is a severe complication following cardiopulmonary bypass (CPB) and is associated with capillary leakage and microcirculatory perfusion disturbances. CPB-induced thrombin release results in capillary hyperperme
Externí odkaz:
https://doaj.org/article/7871f73c22804178aed75e7f5ff74ae3
Autor:
Anoek L. I. van Leeuwen, Nicole A. M. Dekker, Paul Van Slyke, Esther de Groot, Marc G. Vervloet, Joris J. T. H. Roelofs, Matijs van Meurs, Charissa E. van den Brom
Publikováno v:
Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-18 (2021)
Abstract Background Hemorrhagic shock is associated with acute kidney injury and increased mortality. Targeting the endothelial angiopoietin/Tie2 system, which regulates endothelial permeability, previously reduced hemorrhagic shock-induced vascular
Externí odkaz:
https://doaj.org/article/0524479a767440c097e68c72ea84a93a
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-12 (2020)
Abstract Background Microcirculatory perfusion disturbances are associated with increased morbidity and mortality in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Technological advancements made it possible to monitor subling
Externí odkaz:
https://doaj.org/article/0cbd5a62a5b24e5aa3dfcfa1ac8822c7
Autor:
Nicole A. M. Dekker, Anoek L. I. van Leeuwen, Willem W. J. van Strien, Jisca Majolée, Robert Szulcek, Alexander B. A. Vonk, Peter L. Hordijk, Christa Boer, Charissa E. van den Brom
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-10 (2019)
Abstract Background Endothelial hyperpermeability following cardiopulmonary bypass (CPB) contributes to microcirculatory perfusion disturbances and postoperative complications after cardiac surgery. We investigated the postoperative course of renal a
Externí odkaz:
https://doaj.org/article/cc5db07a0166413e81447272e7a71363
Autor:
Christa Boer, Nicole A M Dekker, Peter L. Hordijk, Anoek L I van Leeuwen, Ralph de Vries, Charissa E. van den Brom, Peter M. van de Ven
Publikováno v:
Dekker, N A M, van Leeuwen, A L I, van de Ven, P M, de Vries, R, Hordijk, P L, Boer, C & van den Brom, C E 2020, ' Pharmacological interventions to reduce edema following cardiopulmonary bypass : A systematic review and meta-analysis ', Journal of Critical Care, vol. 56, pp. 63-72 . https://doi.org/10.1016/j.jcrc.2019.12.006
PURPOSE: To compare the effectiveness of different types of pharmacological agents to reduce organ specific edema following cardiopulmonary bypass (CPB).METHODS: Pubmed, Embase.com and Cochrane were searched for studies administrating a pharmacologic
Publikováno v:
Shock, 56(6), 890-900. Lippincott Williams and Wilkins
van Leeuwen, A L I, Borgdorff, M P, Dekker, N A M & van den Brom, C E 2021, ' Therapeutically Targeting Microvascular Leakage In Experimental Hemorrhagic Shock : A Systematic Review and Meta-Analysis ', Shock, vol. 56, no. 6, pp. 890-900 . https://doi.org/10.1097/SHK.0000000000001796
van Leeuwen, A L I, Borgdorff, M P, Dekker, N A M & van den Brom, C E 2021, ' Therapeutically Targeting Microvascular Leakage In Experimental Hemorrhagic Shock : A Systematic Review and Meta-Analysis ', Shock, vol. 56, no. 6, pp. 890-900 . https://doi.org/10.1097/SHK.0000000000001796
BACKGROUND: Microvascular leakage is proposed as main contributor to disturbed microcirculatory perfusion following hemorrhagic shock and fluid resuscitation, leading to organ dysfunction and unfavorable outcome. Currently, no drugs are available to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7174677f4db84c22155d58ba410b3c2
https://research.vumc.nl/en/publications/899b116b-8f33-409d-ad77-ab16d1a638cd
https://research.vumc.nl/en/publications/899b116b-8f33-409d-ad77-ab16d1a638cd
Autor:
Paul Van Slyke, Esther de Groot, Matijs van Meurs, Anoek L I van Leeuwen, Nicole A M Dekker, Joris J. T. H. Roelofs, Marc G. Vervloet, Charissa E. van den Brom
Publikováno v:
Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-18 (2021)
Intensive Care Medicine Experimental, 9(1):23. Springer Science + Business Media
van Leeuwen, A L I, Dekker, N A M, van Slyke, P, de Groot, E, Vervloet, M G, Roelofs, J J T H, van Meurs, M & van den Brom, C E 2021, ' The effect of targeting Tie2 on hemorrhagic shock-induced renal perfusion disturbances in rats ', Intensive Care Medicine Experimental, vol. 9, no. 1, 23, pp. 23 . https://doi.org/10.1186/s40635-021-00389-5
Intensive Care Medicine Experimental, 9(1):23. SpringerOpen
Intensive Care Medicine Experimental
Intensive Care Medicine Experimental, 9(1):23. Springer Science + Business Media
van Leeuwen, A L I, Dekker, N A M, van Slyke, P, de Groot, E, Vervloet, M G, Roelofs, J J T H, van Meurs, M & van den Brom, C E 2021, ' The effect of targeting Tie2 on hemorrhagic shock-induced renal perfusion disturbances in rats ', Intensive Care Medicine Experimental, vol. 9, no. 1, 23, pp. 23 . https://doi.org/10.1186/s40635-021-00389-5
Intensive Care Medicine Experimental, 9(1):23. SpringerOpen
Intensive Care Medicine Experimental
Background Hemorrhagic shock is associated with acute kidney injury and increased mortality. Targeting the endothelial angiopoietin/Tie2 system, which regulates endothelial permeability, previously reduced hemorrhagic shock-induced vascular leakage.
Autor:
Anoek L I van Leeuwen, Christa Boer, Jeannette E. Pankras, Matijs van Meurs, Charissa E van den Brom, Alexander B.A. Vonk, Jill Moser, Nicole A M Dekker, Nicole N. van der Wel, Marc G. Vervloet, Peter L. Hordijk, Hans W.M. Niessen
Publikováno v:
Intensive Care Medicine Experimental
Intensive Care Medicine Experimental, 9(1):30. Springer Science + Business Media
Dekker, N A M, van Leeuwen, A L I, van Meurs, M, Moser, J, Pankras, J E, van der Wel, N N, Niessen, H W, Vervloet, M G, Vonk, A B A, Hordijk, P L, Boer, C & van den Brom, C E 2021, ' Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental cardiopulmonary bypass ', Intensive Care Medicine Experimental, vol. 9, no. 1, 30, pp. 30 . https://doi.org/10.1186/s40635-021-00393-9
Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-19 (2021)
Intensive Care Medicine Experimental, 1-19. SpringerOpen
STARTPAGE=1;ENDPAGE=19;ISSN=2197-425X;TITLE=Intensive Care Medicine Experimental
Intensive Care Medicine Experimental, 9(1):30. Springer Science + Business Media
Dekker, N A M, van Leeuwen, A L I, van Meurs, M, Moser, J, Pankras, J E, van der Wel, N N, Niessen, H W, Vervloet, M G, Vonk, A B A, Hordijk, P L, Boer, C & van den Brom, C E 2021, ' Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental cardiopulmonary bypass ', Intensive Care Medicine Experimental, vol. 9, no. 1, 30, pp. 30 . https://doi.org/10.1186/s40635-021-00393-9
Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-19 (2021)
Intensive Care Medicine Experimental, 1-19. SpringerOpen
STARTPAGE=1;ENDPAGE=19;ISSN=2197-425X;TITLE=Intensive Care Medicine Experimental
Background Acute kidney injury is a severe complication following cardiopulmonary bypass (CPB) and is associated with capillary leakage and microcirculatory perfusion disturbances. CPB-induced thrombin release results in capillary hyperpermeability v
Autor:
Nicole A M Dekker, Christa Boer, A.L. van Leeuwen, Nick J. Koning, C. E. van den Brom, Alexander B.A. Vonk, Paul W. G. Elbers, Dennis Veerhoek
Publikováno v:
Dekker, N A M, Veerhoek, D, Koning, N J, van Leeuwen, A L I, Elbers, P W G, van den Brom, C E, Vonk, A B A & Boer, C 2019, ' Postoperative microcirculatory perfusion and endothelial glycocalyx shedding following cardiac surgery with cardiopulmonary bypass ', Anaesthesia, vol. 74, no. 5, pp. 609-618 . https://doi.org/10.1111/anae.14577, https://doi.org/10.1111/anae.14577
Anaesthesia
Anaesthesia, 74(5), 609-618. Wiley-Blackwell
Anaesthesia
Anaesthesia, 74(5), 609-618. Wiley-Blackwell
We investigated microcirculatory perfusion disturbances following cardiopulmonary bypass in the early postoperative period and whether the course of these disturbances mirrored restoration of endothelial glycocalyx integrity. We performed sublingual