Zobrazeno 1 - 10
of 273
pro vyhledávání: '"Nicole A, Kochan"'
Autor:
Hao Mei, Jeannette Simino, Lianna Li, Fan Jiang, Joshua C. Bis, Gail Davies, W David Hill, Charley Xia, Vilmundur Gudnason, Qiong Yang, Jari Lahti, Jennifer A. Smith, Mirna Kirin, Philip De Jager, Nicola J. Armstrong, Mohsen Ghanbari, Ivana Kolcic, Christopher Moran, Alexander Teumer, Murali Sargurupremraj, Shamsed Mahmud, Myriam Fornage, Wei Zhao, Claudia L. Satizabal, Ozren Polasek, Katri Räikkönen, David C. Liewald, Georg Homuth, Michele Callisaya, Karen A. Mather, B. Gwen Windham, Tatijana Zemunik, Aarno Palotie, Alison Pattie, Sandra van der Auwera, Anbupalam Thalamuthu, David S. Knopman, Igor Rudan, John M. Starr, Katharina Wittfeld, Nicole A. Kochan, Michael E. Griswold, Veronique Vitart, Henry Brodaty, Rebecca Gottesman, Simon R. Cox, Bruce M. Psaty, Eric Boerwinkle, Daniel I. Chasman, Francine Grodstein, Perminder S. Sachdev, Velandai Srikanth, Caroline Hayward, James F. Wilson, Johan G. Eriksson, Sharon L. R. Kardia, Hans J. Grabe, David A. Bennett, M. Arfan Ikram, Ian J. Deary, Cornelia M. van Duijn, Lenore Launer, Annette L. Fitzpatrick, Sudha Seshadri, Jan Bressler, Stephanie Debette, Thomas H. Mosley
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Uncovering the functional relevance underlying verbal declarative memory (VDM) genome-wide association study (GWAS) results may facilitate the development of interventions to reduce age-related memory decline and dementia. Methods
Externí odkaz:
https://doaj.org/article/50a19bd7fce542089e5527e952a66f90
Autor:
Danit G. Saks, Beata Bajorek, Vibeke S. Catts, Adam C. Bentvelzen, Jiyang Jiang, Wei Wen, Karen A. Mather, Anbupalam Thalamuthu, Jessie Huang-Lung, Lisa Nivison-Smith, Lyn R. Griffiths, Robert A. Smith, Adrienne Sexton, Paul James, Tharusha Jayasena, Anne Poljak, Gurpreet K. Hansra, Satoshi Hosoki, Ashley Park, Claudia M. Hillenbrand, Peter van Wijngaarden, Russell J. Chander, Sam Humphrey, Rory Chen, Nicole A. Kochan, Tessa J. Helman, Christopher Levi, Amy Brodtmann, Michael J. O'Sullivan, Romesh Markus, Ken Butcher, Mark Parsons, Jason C. Kovacic, Perminder S. Sachdev
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100225- (2024)
Introduction: Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is a rare genetic condition with a broad phenotypic presentation. This study aims to establish the first Australian cohort of individua
Externí odkaz:
https://doaj.org/article/526edede2535460a845731b93a501cc1
Autor:
Jiahui Hou, Jonathan L. Hess, Nicola Armstrong, Joshua C. Bis, Benjamin Grenier-Boley, Ida K. Karlsson, Ganna Leonenko, Katya Numbers, Eleanor K. O’Brien, Alexey Shadrin, Anbupalam Thalamuthu, Qiong Yang, Ole A. Andreassen, Henry Brodaty, Margaret Gatz, Nicole A. Kochan, Jean-Charles Lambert, Simon M. Laws, Colin L. Masters, Karen A. Mather, Nancy L. Pedersen, Danielle Posthuma, Perminder S. Sachdev, Julie Williams, the Alzheimer’s Disease Neuroimaging Initiative, Chun Chieh Fan, Stephen V. Faraone, Christine Fennema-Notestine, Shu-Ju Lin, Valentina Escott-Price, Peter Holmans, Sudha Seshadri, Ming T. Tsuang, William S. Kremen, Stephen J. Glatt
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Polygenic risk scores (PRSs) can boost risk prediction in late-onset Alzheimer’s disease (LOAD) beyond apolipoprotein E (APOE) but have not been leveraged to identify genetic resilience factors. Here, we sought to identify resilience-confe
Externí odkaz:
https://doaj.org/article/05a0a605763842d88fd8cbd81b52d67b
Autor:
Sharon L. Naismith, Johannes C. Michaelian, Lee-Fay Low, Valerie Arsenova, Inga Mehrani, Katrina Fyfe, Nicole A. Kochan, Susan E. Kurrle, Christopher Rowe, Perminder S. Sachdev
Publikováno v:
BMC Geriatrics, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Memory clinics (MCs) play a key role in accurate and timely diagnoses and treatment of dementia and mild cognitive impairment. However, within Australia, there are little data available on current practices in MCs, which hinder in
Externí odkaz:
https://doaj.org/article/33d2dbe153774ba7b798fa1d0a908e18
Autor:
Katya Numbers, Ben C. P. Lam, John D. Crawford, Nicole A. Kochan, Perminder S. Sachdev, Henry Brodaty
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
BackgroundIndividuals with subjective cognitive complaints (SCCs) are at an increased risk of dementia. Questions remain about participant-reported versus informant-reported SCCs as indicators of future dementia and about longitudinal changes in part
Externí odkaz:
https://doaj.org/article/49a5c785b952463e96df5fcad1e9a594
Autor:
Nithin Manchery, Julie D. Henry, Ben C. P. Lam, Nicole A. Kochan, Alan Deutsch, Henry Brodaty, Perminder S.Sachdev, Matthew R. Nangle
Publikováno v:
BMC Oral Health, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Growing evidence suggests that there is an association between poor oral health and cognitive function in late adulthood. However, most studies to date have relied on cross-sectional research methods that do not permit inferences
Externí odkaz:
https://doaj.org/article/7529d7a6c30249b0a7e9e747caec7840
Autor:
Thanwarat Chantanachai, Morag E. Taylor, Stephen R. Lord, Jasmine Menant, Kim Delbaere, Perminder S. Sachdev, Nicole A. Kochan, Henry Brodaty, Daina L. Sturnieks
Publikováno v:
PeerJ, Vol 10, p e13484 (2022)
Objective Mild cognitive impairment (MCI) is considered an intermediate stage between normal cognitive function and dementia. Fall risk is increased in this group, but there is limited literature exploring specific fall risk factors that may be addre
Externí odkaz:
https://doaj.org/article/8746599785294b3f9577c883fa2807e4
Autor:
Susanne Röhr, Alexander Pabst, Steffi G. Riedel-Heller, Frank Jessen, Yuda Turana, Yvonne S. Handajani, Carol Brayne, Fiona E. Matthews, Blossom C. M. Stephan, Richard B. Lipton, Mindy J. Katz, Cuiling Wang, Maëlenn Guerchet, Pierre-Marie Preux, Pascal Mbelesso, Karen Ritchie, Marie-Laure Ancelin, Isabelle Carrière, Antonio Guaita, Annalisa Davin, Roberta Vaccaro, Ki Woong Kim, Ji Won Han, Seung Wan Suh, Suzana Shahar, Normah C. Din, Divya Vanoh, Martin van Boxtel, Sebastian Köhler, Mary Ganguli, Erin P. Jacobsen, Beth E. Snitz, Kaarin J. Anstey, Nicolas Cherbuin, Shuzo Kumagai, Sanmei Chen, Kenji Narazaki, Tze Pin Ng, Qi Gao, Xinyi Gwee, Henry Brodaty, Nicole A. Kochan, Julian Trollor, Antonio Lobo, Raúl López-Antón, Javier Santabárbara, John D. Crawford, Darren M. Lipnicki, Perminder S. Sachdev, for Cohort Studies of Memory in an International Consortium (COSMIC)
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2020)
Abstract Background Subjective cognitive decline (SCD) is recognized as a risk stage for Alzheimer’s disease (AD) and other dementias, but its prevalence is not well known. We aimed to use uniform criteria to better estimate SCD prevalence across i
Externí odkaz:
https://doaj.org/article/1a5e291acc084db192c86258647f4aad
Autor:
Annette Spooner, Emily Chen, Arcot Sowmya, Perminder Sachdev, Nicole A. Kochan, Julian Trollor, Henry Brodaty
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Data collected from clinical trials and cohort studies, such as dementia studies, are often high-dimensional, censored, heterogeneous and contain missing information, presenting challenges to traditional statistical analysis. There is an urg
Externí odkaz:
https://doaj.org/article/241adb643d7845fea517bcfa07bbbc26
Autor:
Xingxing Cao, Tao Liu, Jiyang Jiang, Hao Liu, Jing Zhang, Nicole A. Kochan, Haijun Niu, Henry Brodaty, Perminder S. Sachdev, Wei Wen
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
In this research, we investigated the alterations in the directionality and strength of regional interactions within functionally changed brain networks and their relationship to cognitive decline during the aging process in normal elderly individual
Externí odkaz:
https://doaj.org/article/0764a53fb6c147949c9cf2f4478cf903