Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Nicole, Schneider"'
Autor:
Patrick Carius, Annemarie Jungmann, Marco Bechtel, Alexander Grißmer, Annette Boese, Gilles Gasparoni, Abdulrahman Salhab, Ralf Seipelt, Klaus Urbschat, Clémentine Richter, Carola Meier, Denisa Bojkova, Jindrich Cinatl, Jörn Walter, Nicole Schneider‐Daum, Claus‐Michael Lehr
Publikováno v:
Advanced Science, Vol 10, Iss 8, Pp n/a-n/a (2023)
Abstract In the development of orally inhaled drug products preclinical animal models regularly fail to predict pharmacological as well as toxicological responses in humans. Models based on human cells and tissues are potential alternatives to animal
Externí odkaz:
https://doaj.org/article/bd657f46b48c4b599d1780adf01cc0eb
Autor:
Pauline Zamprogno, Simon Wüthrich, Sven Achenbach, Giuditta Thoma, Janick D. Stucki, Nina Hobi, Nicole Schneider-Daum, Claus-Michael Lehr, Hanno Huwer, Thomas Geiser, Ralph A. Schmid, Olivier T. Guenat
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Zamprogno et al. report a lung-on-a-chip of the second generation that mimics an array of alveoli with in vivo-like dimensions, based on a thin, stretchable collagen-elastin membrane used to reproduce the air-blood barrier functions. The membrane is
Externí odkaz:
https://doaj.org/article/b58e7abc6fe5449390fc885d757f1445
Autor:
Arunima Sengupta, Nuria Roldan, Mirjam Kiener, Laurène Froment, Giulia Raggi, Theo Imler, Lea de Maddalena, Aude Rapet, Tobias May, Patrick Carius, Nicole Schneider-Daum, Claus-Michael Lehr, Marianna Kruithof-de Julio, Thomas Geiser, Thomas Michael Marti, Janick D. Stucki, Nina Hobi, Olivier T. Guenat
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
The evaluation of inhalation toxicity, drug safety and efficacy assessment, as well as the investigation of complex disease pathomechanisms, are increasingly relying on in vitro lung models. This is due to the progressive shift towards human-based sy
Externí odkaz:
https://doaj.org/article/18439d6b7ad04cbb88aed125762e6885
Autor:
Patrick Carius, Aurélie Dubois, Morvarid Ajdarirad, Arbel Artzy-Schnirman, Josué Sznitman, Nicole Schneider-Daum, Claus-Michael Lehr
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Complex in vitro models, especially those based on human cells and tissues, may successfully reduce or even replace animal models within pre-clinical development of orally inhaled drug products. Microfluidic lung-on-chips are regarded as especially p
Externí odkaz:
https://doaj.org/article/7ec2a12cd41f4e0abff23f8fdcffd383
Autor:
Robert Richter, Mohamed.A.M. Kamal, Mariel A. García-Rivera, Jerome Kaspar, Maximilian Junk, Walid A.M. Elgaher, Sanjay Kumar Srikakulam, Alexander Gress, Anja Beckmann, Alexander Grißmer, Carola Meier, Michael Vielhaber, Olga Kalinina, Anna K.H. Hirsch, Rolf W. Hartmann, Mark Brönstrup, Nicole Schneider-Daum, Claus-Michael Lehr
Publikováno v:
Materials Today Bio, Vol 8, Iss , Pp 100084- (2020)
The pipeline of antibiotics has been for decades on an alarmingly low level. Considering the steadily emerging antibiotic resistance, novel tools are needed for early and easy identification of effective anti-infective compounds. In Gram-negative bac
Externí odkaz:
https://doaj.org/article/abcd928f0e8c4f0e83637af5a24dae36
Autor:
Mohammed Ali Selo, Anne-Sophie Delmas, Lisa Springer, Viktoria Zoufal, Johannes A. Sake, Caoimhe G. Clerkin, Hanno Huwer, Nicole Schneider-Daum, Claus-Michael Lehr, Sabrina Nickel, Oliver Langer, Carsten Ehrhardt
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Multidrug resistance-associated protein-1 (MRP1/ABCC1) is highly expressed in human lung tissues. Recent studies suggest that it significantly affects the pulmonary disposition of its substrates, both after pulmonary and systemic administration. To b
Externí odkaz:
https://doaj.org/article/dda9e160b03342e883773c34d2c21a53
Autor:
Renan J.R. Fernandes, Aaron Gee, Nicole Schneider, Andrew J. Kanawati, Christopher S. Bailey, Parham Rasoulinejad
Publikováno v:
World Neurosurgery. 162:e225-e234
We sought to evaluate the accuracy of using patient-specific drill guides to place bilateral laminar screws in C1 and C2.Nine cervical specimens (8 males; mean age: 66.6 [56-73]) with the occiput attached (C0-C3) were used in this study. Preoperative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677665bf16773cc27be6237a33e912c1
https://doi.org/10.1016/j.wneu.2022.02.126
https://doi.org/10.1016/j.wneu.2022.02.126
Autor:
Michael Detmar, Maija Bry, Nicole Schneider, Manuela Jost, Stefania Martino, David Aebischer, Sinem Karaman, Steven T. Proulx, Annamari K. Alitalo
PDF - 120K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba03ee379c39c3940f0f0f5c6c006018
https://doi.org/10.1158/0008-5472.22397033.v1
https://doi.org/10.1158/0008-5472.22397033.v1
Autor:
Michael Detmar, Maija Bry, Nicole Schneider, Manuela Jost, Stefania Martino, David Aebischer, Sinem Karaman, Steven T. Proulx, Annamari K. Alitalo
PDF - 1898K, Expression of neuropilins in skin and tumors of wild-type mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe1ca870eb88d200c4bc0da39de31f1
https://doi.org/10.1158/0008-5472.22397036
https://doi.org/10.1158/0008-5472.22397036
Autor:
Michael Detmar, Maija Bry, Nicole Schneider, Manuela Jost, Stefania Martino, David Aebischer, Sinem Karaman, Steven T. Proulx, Annamari K. Alitalo
PDF - 1898K, VEGR-3, MECA32 and CD68 expression in DMBA-TPA treated skin and tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aab2644ac9856c5147001b627310d9a
https://doi.org/10.1158/0008-5472.22397039
https://doi.org/10.1158/0008-5472.22397039