Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nicole, Groh"'
Autor:
Marie C. Lechler, Emily D. Crawford, Nicole Groh, Katja Widmaier, Raimund Jung, Janine Kirstein, Jonathan C. Trinidad, Alma L. Burlingame, Della C. David
Publikováno v:
Cell Reports, Vol 18, Iss 2, Pp 454-467 (2017)
Summary: Low-complexity “prion-like” domains in key RNA-binding proteins (RBPs) mediate the reversible assembly of RNA granules. Individual RBPs harboring these domains have been linked to specific neurodegenerative diseases. Although their aggre
Externí odkaz:
https://doaj.org/article/b5d785eb2438408095c363dff5f3c2d9
Autor:
Nicole Groh, Anika Bühler, Chaolie Huang, Ka Wan Li, Pim van Nierop, August B. Smit, Marcus Fändrich, Frank Baumann, Della C. David
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
Aging is the most important risk factor for neurodegenerative diseases associated with pathological protein aggregation such as Alzheimer’s disease. Although aging is an important player, it remains unknown which molecular changes are relevant for
Externí odkaz:
https://doaj.org/article/6922cd6cd3ef43cca1c2695e5e6e5d1e
Autor:
Michael Matthew McClay, Angela Shields, Stephen E. Nicolson, Jo Ellen Wilson, Marissa Baudino, John Bone, Lisa Venanzi, Stephen S. O'Connor, Brittany Nicole Groh
Publikováno v:
Psychiatric Services. 69:657-663
Evidence suggests that suicide attempts by self-inflicted gunshot wound (GSW) are underreported and may in turn affect disposition following hospitalization. This study aimed to evaluate the clinical characteristics and use of services among individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd786fd9074c39e244e5d27121279fc
https://doi.org/10.1176/appi.ps.201700130
https://doi.org/10.1176/appi.ps.201700130
Autor:
Erin Carney, Peter M. Gutierrez, Barbara Kaminer, Lora L. Johnson, David A. Jobes, Brittany Nicole Groh, Stephen S. O'Connor
Publikováno v:
Archives of Suicide Research. 23:15-33
The current study investigated the impact of adding the Suicide Status Form (SSF) to a suicide-focused group therapy for veterans recently discharged from an inpatient psychiatry setting. A sample of 141 veterans was enrolled and randomized into a Us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4342b5b4e0e268b4adcdeed630dc3d3
https://doi.org/10.1080/13811118.2017.1402722
https://doi.org/10.1080/13811118.2017.1402722
Publikováno v:
Journal of Visualized Experiments.
In the last decades, the prevalence of neurodegenerative disorders, such as Alzheimer's disease (AD) and Parkinson's disease (PD), has grown. These age-associated disorders are characterized by the appearance of protein aggregates with fibrillary str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad7446ecc6e6c89bc611ed3719cfc58
https://doi.org/10.3791/56464
https://doi.org/10.3791/56464
Autor:
Janine Kirstein, Katja Widmaier, Jonathan C. Trinidad, Marie C. Lechler, Emily D. Crawford, Della C. David, Nicole Groh, Alma L. Burlingame, Raimund Jung
Publikováno v:
Cell reports 18(2), 454-467 (2017). doi:10.1016/j.celrep.2016.12.033
Cell Reports
Cell reports, 18(2): 454–467
Cell Reports, Vol 18, Iss 2, Pp 454-467 (2017)
Cell Reports
Cell reports, 18(2): 454–467
Cell Reports, Vol 18, Iss 2, Pp 454-467 (2017)
Summary Low-complexity “prion-like” domains in key RNA-binding proteins (RBPs) mediate the reversible assembly of RNA granules. Individual RBPs harboring these domains have been linked to specific neurodegenerative diseases. Although their aggreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5af5e2785ae020a809f32fa789c3e4
Autor:
Nicole, Groh, Ivan, Gallotta, Marie C, Lechler, Chaolie, Huang, Raimund, Jung, Della C, David
Publikováno v:
JoVE journal Biology(129), 56464 (2017). doi:10.3791/56464
In the last decades, the prevalence of neurodegenerative disorders, such as Alzheimer's disease (AD) and Parkinson's disease (PD), has grown. These age-associated disorders are characterized by the appearance of protein aggregates with fibrillary str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8f9331a1fe485b30cbb1aa6fa5233d53
Autor:
Ralf Dittrich, Michael G. Schrauder, Matthias W. Beckmann, Ben Fabry, Sonja Oeser, Juergen Dittmer, Astrid Polier, Michael P. Lux, Inge Hoffmann, David L. Wachter, Peter A. Fasching, Pamela L. Strissel, Christian R. Loehberg, Ina Brandt, Nicole Groh, Angela Dittmer, Thorsten Koch, Florentine Koppitz, Reiner Strick, Willi A. Kalender, Andreas Mueller, Laura Lotz
Publikováno v:
Biochemical pharmacology. 83(4)
PI3K/Akt/mTOR and p53 signaling pathways are frequently deregulated in tumors. The anticancer drug RAD001 (everolimus) is a known mTOR-inhibitor, but mTOR-inhibition leads to phosphorylation of Akt inducing resistance against RAD001 treatment. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c63e9ba0cc1877e39c77e0e9b00fbf
https://pubmed.ncbi.nlm.nih.gov/22142888
https://pubmed.ncbi.nlm.nih.gov/22142888