Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Nicole, Baumgarth"'
Autor:
Ahmed M. Alhassan, Venktesh S. Shirure, Jean Luo, Bryan B. Nguyen, Zachary A. Rollins, Bhupinder S. Shergill, Xiangdong Zhu, Nicole Baumgarth, Steven C. George
Publikováno v:
Advanced NanoBiomed Research, Vol 4, Iss 6, Pp n/a-n/a (2024)
Assessing B cell affinity to pathogen‐specific antigens prior to or following exposure could facilitate the assessment of immune status. Current standard tools to assess antigen‐specific B cell responses focus on equilibrium binding of the secret
Externí odkaz:
https://doaj.org/article/7c45425654df4ba6af91d65202c169b5
Autor:
Shannon Eileen McGettigan, Lazaro Emilio Aira, Gaurav Kumar, Romain Ballet, Eugene C. Butcher, Nicole Baumgarth, Gudrun F. Debes
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract IL-10+ B cells are critical for immune homeostasis and restraining immune responses in infection, cancer, and inflammation; however, the signals that govern IL-10+ B cell differentiation are ill-defined. Here we find that IL-10+ B cells expa
Externí odkaz:
https://doaj.org/article/4b636fe12b824d0485d4e18d2d529d62
Autor:
Jonathan H. Lam, Nicole Baumgarth
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Extrafollicular plasmablast responses (EFRs) are considered to generate antibodies of low affinity that offer little protection from infections. Paradoxically, high avidity antigen-B cell receptor engagement is thought to be the main driver
Externí odkaz:
https://doaj.org/article/e57477f29cf74a34bc679c921482a909
Autor:
Khalid H. Bhat, Saurabh Priyadarshi, Sarah Naiyer, Xinyan Qu, Hammad Farooq, Eden Kleiman, Jeffery Xu, Xue Lei, Jose F. Cantillo, Robert Wuerffel, Nicole Baumgarth, Jie Liang, Ann J. Feeney, Amy L. Kenter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Here the authors show enhancers in the Igh locus play a major role in configuring locus architecture and in V(D)J recombination, and identify a link between enhancer hub formation, locus contraction and cohesin-mediated loop extrusion.
Externí odkaz:
https://doaj.org/article/ba000a65998d49268875ffe123c8814e
Autor:
Nicole Baumgarth
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)
Externí odkaz:
https://doaj.org/article/be9d2b04cc8342c8910e168bb9859f23
Autor:
Scott P Souza, Samantha D Splitt, Juan C Sànchez-Arcila, Julia A Alvarez, Jessica N Wilson, Safuwra Wizzard, Zheng Luo, Nicole Baumgarth, Kirk D C Jensen
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010081 (2021)
Protective immunity to parasitic infections has been difficult to elicit by vaccines. Among parasites that evade vaccine-induced immunity is Toxoplasma gondii, which causes lethal secondary infections in chronically infected mice. Here we report that
Externí odkaz:
https://doaj.org/article/51630f80687a4dba9e15b4b67857c227
Autor:
Jason R. Bobe, Brandon L. Jutras, Elizabeth J. Horn, Monica E. Embers, Allison Bailey, Robert L. Moritz, Ying Zhang, Mark J. Soloski, Richard S. Ostfeld, Richard T. Marconi, John Aucott, Avi Ma'ayan, Felicia Keesing, Kim Lewis, Choukri Ben Mamoun, Alison W. Rebman, Mecaila E. McClune, Edward B. Breitschwerdt, Panga Jaipal Reddy, Ricardo Maggi, Frank Yang, Bennett Nemser, Aydogan Ozcan, Omai Garner, Dino Di Carlo, Zachary Ballard, Hyou-Arm Joung, Albert Garcia-Romeu, Roland R. Griffiths, Nicole Baumgarth, Brian A. Fallon
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Lyme disease (also known as Lyme borreliosis) is the most common vector-borne disease in the United States with an estimated 476,000 cases per year. While historically, the long-term impact of Lyme disease on patients has been controversial, mounting
Externí odkaz:
https://doaj.org/article/ca9119db6ce348ba901a40ee47164699
Autor:
Nicole Baumgarth
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 209(9)
This Pillars of Immunology article is a commentary on “Positive Selection of Natural Autoreactive B Cells,” a pivotal article written by K. Hayakawa, M. Asano, S. A. Shinton, M. Gui, D. Allman, C. L. Stewart, J. Silver, and R. R. Hardy, and publi
Autor:
Sam T. Donta, Leith J. States, Wendy A. Adams, Troy Bankhead, Nicole Baumgarth, Monica E. Embers, Robert B. Lochhead, Brian Stevenson
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
An understanding of the pathogenesis and pathophysiology of Lyme disease is key to the ultimate care of patients with Lyme disease. To better understand the various mechanisms underlying the infection caused by Borrelia burgdorferi, the Pathogenesis
Externí odkaz:
https://doaj.org/article/e67b6010a66548ae8ddc98a3e67e583f
Publikováno v:
Physiology. 38
Background: Vagus nerve stimulation (VNS) has recently been introduced as a nonpharmacological therapy for disease characterized by an exacerbated immune response, with clinical trials demonstrating its efficacy for autoimmunity and sepsis by reducin