Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus

Autor: Katy Poncin, Agnès Roba, Ravikumar Jimmidi, Georges Potemberg, Antonella Fioravanti, Nayla Francis, Kévin Willemart, Nicolas Zeippen, Arnaud Machelart, Emanuele G. Biondi, Eric Muraille, Stéphane P. Vincent, Xavier De Bolle

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

It is assumed that intracellular pathogenic bacteria must cope with DNA alkylating stress within host cells. Here, Poncin et al. show that the pathogen Brucella abortus does encounter alkylating stress within macrophages, and shed light into the path

Externí odkaz: https://doaj.org/article/0e9cb03fdb914652b78daf4b8a72caac

Correction: A lineage-specific rapid diagnostic test (Chagas Sero K-SeT) identifies Brazilian Trypanosoma cruzi II/V/VI reservoir hosts among diverse mammalian orders.

Autor: Mairi C W McClean, Tapan Bhattacharyya, Pascal Mertens, Niamh Murphy, Quentin Gilleman, Yves Gustin, Nicolas Zeippen, Samanta C C Xavier, Ana M Jansen, Michael A Miles

Publikováno v: PLoS ONE, Vol 15, Iss 4, p e0231566 (2020)

[This corrects the article DOI: 10.1371/journal.pone.0227828.].

Externí odkaz: https://doaj.org/article/20a0125c70d54562b139287658f0ae98

Lineage-specific rapid diagnostic tests can resolve Trypanosoma cruzi TcII/V/VI ecological and epidemiological associations in the Argentine Chaco

Autor: Michael A. Miles, Pascal Mertens, Ricardo E. Gürtler, Quentin Gilleman, Niamh Murphy, M. Victoria Cardinal, Natalia Paula Macchiaverna, Yves Gustin, Tapan Bhattacharyya, Nicolas Zeippen

Publikováno v: Parasites & Vectors, Vol 12, Iss 1, Pp 1-11 (2019)
Parasites & Vectors

Background Trypanosoma cruzi, the protozoan agent of Chagas disease, is comprised of at least 6 genetic lineages (TcI-TcVI). Their geographical distribution, clinical associations and reservoir hosts are not fully elucidated, as genotyping is hampere

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79cc79b0dfd6b43769c26092aed6c593
http://link.springer.com/article/10.1186/s13071-019-3681-7

Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus

Autor: Xavier De Bolle, Arnaud Machelart, Katy Poncin, Eric Muraille, Emanuele G. Biondi, Nayla Francis, Agnès Roba, Kevin Willemart, Nicolas Zeippen, Georges Potemberg, Antonella Fioravanti, Stéphane P. Vincent, Ravikumar Jimmidi

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-12516-8⟩
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-12516-8⟩
Poncin, K, Roba, A, Jimmidi, R, Potemberg, G, Fioravanti, A, Francis, N, Willemart, K, Zeippen, N, Machelart, A, Biondi, E G, Muraille, E, Vincent, S P & De Bolle, X 2019, ' Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus ', Nature Communications, vol. 10, no. 1, 4847, pp. 4847 . https://doi.org/10.1038/s41467-019-12516-8
Nature communications, 10 (1
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

It is assumed that intracellular pathogenic bacteria have to cope with DNA alkylating stress within host cells. Here we use single-cell reporter systems to show that the pathogen Brucella abortus does encounter alkylating stress during the first hour

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb1d24f7e59a59df9acf427e3b9dd9bd
https://biblio.vub.ac.be/vubir/occurrence-and-repair-of-alkylating-stress-in-the-intracellular-pathogen-brucella-abortus(32eb28a2-69fe-4808-870b-f7c0710f221e).html