Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Nicolas Y. Masse"'
Autor:
Pierre De Rossi, Toshihiro Nomura, Robert J. Andrew, Nicolas Y. Masse, Vandana Sampathkumar, Timothy F. Musial, Ari Sudwarts, Aleksandra J. Recupero, Thomas Le Metayer, Mitchell T. Hansen, Ha-Na Shim, Sofia V. Krause, David J. Freedman, Vytas P. Bindokas, Narayanan Kasthuri, Daniel A. Nicholson, Anis Contractor, Gopal Thinakaran
Publikováno v:
Cell Reports, Vol 30, Iss 10, Pp 3520-3535.e7 (2020)
Summary: BIN1, a member of the BAR adaptor protein family, is a significant late-onset Alzheimer disease risk factor. Here, we investigate BIN1 function in the brain using conditional knockout (cKO) models. Loss of neuronal Bin1 expression results in
Externí odkaz:
https://doaj.org/article/3ee20aa26dbb4398a318c588047a8aa8
Publikováno v:
eLife, Vol 10 (2021)
Comparing sequential stimuli is crucial for guiding complex behaviors. To understand mechanisms underlying sequential decisions, we compared neuronal responses in the prefrontal cortex (PFC), the lateral intraparietal (LIP), and medial intraparietal
Externí odkaz:
https://doaj.org/article/4c58d171860b42d7a87f527e790ec7be
The brains of all animals are plastic, allowing us to form new memories, adapt to new environments, and to learn new tasks. What is less clear is how much plasticity is required to perform these cognitive functions: does learning require widespread p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::221f88a7bf510e915d14768346200d42
https://doi.org/10.1101/2022.05.09.491102
https://doi.org/10.1101/2022.05.09.491102
Autor:
Jackson J. Cone, John H. R. Maunsell, Morgan L. Bade, David J. Freedman, Nicolas Y. Masse, E. Page
Publikováno v:
J Neurosci
Whenever the retinal image changes, some neurons in visual cortex increase their rate of firing whereas others decrease their rate of firing. Linking specific sets of neuronal responses with perception and behavior is essential for understanding mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f441832bb65e4613aea59413b5306fe2
https://doi.org/10.1523/jneurosci.1124-20.2020
https://doi.org/10.1523/jneurosci.1124-20.2020
Publikováno v:
Nat Neurosci
Recently it has been proposed that information in working memory (WM) may not always be stored in persistent neuronal activity but can be maintained in 'activity-silent' hidden states, such as synaptic efficacies endowed with short-term synaptic plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d349f878f1ece1e77929bfb80130e04e
https://doi.org/10.1038/s41593-019-0414-3
https://doi.org/10.1038/s41593-019-0414-3
Autor:
Oliver Zhu, Sruthi K. Swaminathan, Matthew C Rosen, Yang Zhou, David J. Freedman, Nicolas Y. Masse
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
The ability to compare sequential sensory inputs is crucial for solving many behavioral tasks. To understand the neuronal mechanisms underlying sequential decisions, we compared neuronal responses in the prefrontal cortex (PFC) and the lateral and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be43a984e610185e61f8df2e9d08c2d6
https://pubmed.ncbi.nlm.nih.gov/34491201
https://pubmed.ncbi.nlm.nih.gov/34491201
Autor:
Nicolas Y. Masse, Jackson J. Cone, E. Page, John H. R. Maunsell, David J. Freedman, Morgan L. Bade
Whenever the retinal image changes some neurons in visual cortex increase their rate of firing, while others decrease their rate of firing. Linking specific sets of neuronal responses with perception and behavior is essential for understanding mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f69a95d72b757df588eaafce5bdeea
Publikováno v:
The Journal of Neuroscience. 37:6098-6112
Persistent activity within the frontoparietal network is consistently observed during tasks that require working memory. However, the neural circuit mechanisms underlying persistent neuronal encoding within this network remain unresolved. Here, we as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b73d93af81234fe67ec15a3d2eb3ee4
https://doi.org/10.1523/jneurosci.3903-16.2017
https://doi.org/10.1523/jneurosci.3903-16.2017
Publikováno v:
Trends Cogn Sci
A traditional view of short-term working memory (STM) is that task-relevant information is maintained 'online' in persistent spiking activity. However, recent experimental and modeling studies have begun to question this long-held belief. In this rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::910b9c24e83e3550a89ce28b255fe5d2
https://pubmed.ncbi.nlm.nih.gov/32007384
https://pubmed.ncbi.nlm.nih.gov/32007384