Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Nicolas Vignon-Zellweger"'
Publikováno v:
Kidney & Blood Pressure Research, Vol 41, Iss 6, Pp 770-780 (2016)
Background/Aims: ET-1 has independent effects on blood pressure regulation in vivo, it is involved in tubular water and salt excretion, promotes constriction of smooth muscle cells, modulates sympathetic nerve activity, and activates the liberation o
Externí odkaz:
https://doaj.org/article/67426854317449cbb93df18f88b54b12
Autor:
Susi Heiden, Nicolas Vignon-Zellweger, Shigeru Masuda, Keiko Yagi, Kazuhiko Nakayama, Masashi Yanagisawa, Noriaki Emoto
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88730 (2014)
BACKGROUND: Endothelin-1 participates in the pathophysiology of heart failure. The reasons for the lack of beneficial effect of endothelin antagonists in heart failure patients remain however speculative. The anti-apoptotic properties of ET-1 on card
Externí odkaz:
https://doaj.org/article/54cc3e07a27944f99e35a1d71a9d40d2
Autor:
Katharina Relle, Berthold Hocher, Nicolas Vignon-Zellweger, Franz Theuring, Jan Rahnenführer, Karima Schwab
Publikováno v:
Life Sciences. 118:219-225
Aims: The nitric oxide and endothelin systems are key components of a local paracrine hormone network in the heart. We previously reported that diastolic dysfunction observed in mice lacking the endothelial nitric oxide synthase (eNOS-/-) can be prev
Autor:
Julia Straube, Matthias Barton, Louisane Desbiens, Rheure A Lopes, Noriaki Emoto, Susi Heiden, Adviye Ergul, Joseph A. Cacioppo, Thomas Leurgans, Masashi Yanagisawa, Danielle Kamato, Raphael Wurm, Nicolas Vignon-Zellweger, Rebecca Moorhouse
Publikováno v:
Emoto, N, Vignon-Zellweger, N, Lopes, R A M, Cacioppo, J, Desbiens, L, Kamato, D, Leurgans, T, Moorhouse, R, Straube, J, Wurm, R, Heiden, S, Ergul, A, Yanagisawa, M & Barton, M 2014, ' 25 Years of endothelin research : The next generation ', Life Sciences, vol. 118, no. 2, pp. 77-86 . https://doi.org/10.1016/j.lfs.2014.07.035
In the past three decades, endothelin and endothelin receptor antagonists have received great scientific and clinical interest, leading to the publication of more than 27,000 scientific articles since its discovery. The Thirteenth International Confe
Autor:
Ken-ichi Hirata, Yoko Suzuki, Kazuhiko Nakayama, Nicolas Vignon-Zellweger, Noriaki Emoto, Anggoro Budi Hartopo, Keiko Yagi
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 48:465-476
Endothelin-1 (ET-1) has been shown to be involved in human pulmonary fibrosis. However, recent clinical trials targeting the ET-1 pathway with ET-1 receptor antagonists failed to achieve beneficial outcomes. Another strategy opposing the actions of E
Autor:
Kazuhiko Nakayama, Suko Adiarto, Noriaki Emoto, Nicolas Vignon-Zellweger, Susi Heiden, Masashi Yanagisawa, Keiko Yagi
Publikováno v:
Life Sciences. 91:651-657
Aims Hypertensive patients develop cardiac hypertrophy and fibrosis with increased stiffness, contractile deficit and altered perfusion. Angiotensin II (AngII) is an important factor in the promotion of this pathology. The effects of AngII are partly
Autor:
Boris Neumann, Andreas Fischer, Robert Stein, Peter R. Jungblut, Karima Schwab, Christian Scheler, Nicolas Vignon-Zellweger, Franz Theuring
Publikováno v:
PROTEOMICS. 11:3887-3904
Elevated cardiovascular risk in postmenopausal women and beneficial actions of estrogen replacement in animal models have been related to protective effects of estrogens. However, randomized trials of hormone replacement therapy with synthetic estrog
Autor:
Barbara Albrecht-Küpper, Karima Schwab, Franz Theuring, Philipp Kalk, Patrick Seider, Markus Alter, Nicolas Vignon-Zellweger, Juliya Sharkovska, Elodie Kienlen, Katharina Relle, Susi Heiden, Johannes-Peter Stasch, Berthold Hocher
Publikováno v:
Journal of Hypertension. 29:961-970
Background The cardiac nitric oxide and endothelin-1 (ET-1) systems are closely linked and play a critical role in cardiac physiology. The balance between both systems is often disturbed in cardiovascular diseases. To define the cardiac effect of exc
Autor:
Nicolas Vignon-Zellweger
Publikováno v:
PLoS ONE
Autor:
Hirowati, Ali, Noriaki, Emoto, Keiko, Yagi, Nicolas, Vignon-Zellweger, Kazuhiko, Nakayama, Kinta, Hatakeyama, Yujiro, Asada, Yoshiyuki, Rikitake, Ken-Ichi, Hirata
Publikováno v:
The Kobe journal of medical sciences. 59(4)
Inhibition of atherosclerosis progression has long been the subject of intensive pathophysiologic investigations. The identification of a novel target molecule to redeem the cellular processes remains a major challenge in cardiology. Signal peptide C