Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nicolas Vallières"'
Autor:
Floriane Bretheau, Adrian Castellanos-Molina, Dominic Bélanger, Maxime Kusik, Benoit Mailhot, Ana Boisvert, Nicolas Vallières, Martine Lessard, Matthias Gunzer, Xiaoyu Liu, Éric Boilard, Ning Quan, Steve Lacroix
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
The neuroimmune interactions driving secondary degeneration in the injured spinal cord remain elusive. Here, the authors reveal that damaged microglia release IL-1α, resulting in neutrophil infiltration and the loss of mature oligodendrocytes throug
Externí odkaz:
https://doaj.org/article/f3c3924c344a4760823aae7c0f49225c
Autor:
Paul R Fortin, Marie-Ève Tremblay, Eric Boilard, Matthias Gunzer, Isabelle Allaeys, Tania Levesque, Louis Flamand, Audrée Laroche, Micaël Carrier, Denis Soulet, Marc Bazin, Nicolas Vallières, Steve Lacroix
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)
Externí odkaz:
https://doaj.org/article/071daa2899ca4b979eb7062e5be3f225
Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury
Autor:
Victor Bellver-Landete, Floriane Bretheau, Benoit Mailhot, Nicolas Vallières, Martine Lessard, Marie-Eve Janelle, Nathalie Vernoux, Marie-Ève Tremblay, Tobias Fuehrmann, Molly S. Shoichet, Steve Lacroix
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
The role of microglia following spinal cord injury is not fully understood. Here, using transgenic approaches to selectively label microglia and not macrophages in mice, the authors show that microglia are highly active and accumulate at the edge of
Externí odkaz:
https://doaj.org/article/2fc70e1ee997470e9a54f3634a92fb6e
Autor:
Audrée Laroche, Micaël Carrier, Denis Soulet, Marc Bazin, Tania Levesque, Isabelle Allaeys, Nicolas Vallières, Matthias Gunzer, Louis Flamand, Steve Lacroix, Marie-Ève Tremblay, Paul R Fortin, Eric Boilard
Publikováno v:
Brain Injury in SLE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0f7e565c7d758a68b61265cb8dd5daf
https://doi.org/10.1136/lupus-2022-lupus21century.16
https://doi.org/10.1136/lupus-2022-lupus21century.16
Autor:
Audree Laroche, Denis Soulet, Marc Bazin, Tania Levesque, Isabelle Allaeys, Nicolas Vallières, Matthias Gunzer, Louis Flamand, Steve Lacroix, Eric Boilard
Publikováno v:
Blood advances. 6(12)
Immune complexes form in systemic disorders such as rheumatological, autoimmune, and allergic diseases or in response to infections or medications. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) adenoviral vector vaccines have been asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339e2858fab1694e6282b41b77f46e3b
https://pubmed.ncbi.nlm.nih.gov/35452514
https://pubmed.ncbi.nlm.nih.gov/35452514
Autor:
Nicolas Vallières, Steve Lacroix, Dominic Belanger, Martine Lessard, Floriane Bretheau, Adrian Castellanos-Molina, Maxime Kusik, Benoit Mailhot, Ning Quan, Xiaoyu Liu
Spinal cord injury (SCI) triggers neuroinflammation, and subsequently secondary degeneration and oligodendrocyte (OL) death. We report that the alarmin interleukin (IL)-1α is released by damaged microglia after SCI. Intra-cisterna magna injection of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06555dce6460a28ab579a960ef24235b
https://doi.org/10.21203/rs.3.rs-580331/v1
https://doi.org/10.21203/rs.3.rs-580331/v1
Autor:
Floriane Bretheau, Adrian Castellanos-Molina, Dominic Bélanger, Maxime Kusik, Benoit Mailhot, Ana Boisvert, Nicolas Vallières, Martine Lessard, Matthias Gunzer, Xiaoyu Liu, Éric Boilard, Ning Quan, Steve Lacroix
Publikováno v:
Nature communications. 13(1)
Spinal cord injury (SCI) triggers neuroinflammation, and subsequently secondary degeneration and oligodendrocyte (OL) death. We report that the alarmin interleukin (IL)−1α is produced by damaged microglia after SCI. Intra-cisterna magna injection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631b698ccf2a56d28925f47767faa415
https://pubmed.ncbi.nlm.nih.gov/36184639
https://pubmed.ncbi.nlm.nih.gov/36184639
Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury
Autor:
Molly S. Shoichet, Nicolas Vallières, Tobias Fuehrmann, Steve Lacroix, Marie-Eve Janelle, Nathalie Vernoux, Marie-Ève Tremblay, Benoit Mailhot, Martine Lessard, Floriane Bretheau, Victor Bellver-Landete
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Nature Communications
Nature Communications
The role of microglia in spinal cord injury (SCI) remains poorly understood and is often confused with the response of macrophages. Here, we use specific transgenic mouse lines and depleting agents to understand the response of microglia after SCI. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27881ead8538d74513b709282f4549ea
http://link.springer.com/article/10.1038/s41467-019-08446-0
http://link.springer.com/article/10.1038/s41467-019-08446-0
Autor:
Steve Lacroix, Frédéric Bretzner, Benoit Barrette, Daniel Côté, Nicolas Vallières, Marlon R. Schneider, Linda Xiang Wang, Mohammed Filali, Louise Thiry, Erik Bélanger
Publikováno v:
Glia. 65:657-669
When a nerve fiber is cut or crushed, the axon segment that is separated from the soma degenerates distal from the injury in a process termed Wallerian degeneration (WD). C57BL/6OlaHsd-WldS (WldS ) mutant mice exhibit significant delays in WD. This r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3631459830d9c0b8b6f93513bb388c36
https://doi.org/10.1002/glia.23119
https://doi.org/10.1002/glia.23119
Autor:
Steve Lacroix, Karl J.L. Fernandes, Nicolas Vallières, Xiaofei Li, Nicolas Guérout, Anne Aumont, Fanie Barnabé-Heider, Chaima Chalfouh, Axel Honoré, Elisa M. Floriddia, Konstantinos Toskas
Publikováno v:
Experimental Cell Research
Experimental Cell Research, Elsevier, 2018, 368 (1), pp.84-100. ⟨10.1016/j.yexcr.2018.04.017⟩
Experimental Cell Research, Elsevier, 2018, 368 (1), pp.84-100. ⟨10.1016/j.yexcr.2018.04.017⟩
Development of the spinal cord requires dynamic and tightly controlled expression of numerous transcription factors. Forkhead Box protein J1 (FoxJ1) is a transcription factor involved in ciliogenesis and is specifically expressed in ependymal cells (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f5bb28157c9695737b0086e57cf78e1
https://hal.archives-ouvertes.fr/hal-02366098
https://hal.archives-ouvertes.fr/hal-02366098