Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Nicolas Tran-Khanh"'
Autor:
Marc Lavertu, Mario Jolicoeur, Geneviève Lavallée, Nicolas Tran-Khanh, Jessica Guzmán-Morales, Caroline D. Hoemann
Publikováno v:
Molecules, Vol 18, Iss 1, Pp 1015-1035 (2013)
Chitosan is a biocompatible polysaccharide composed of glucosamine and N-acetylglucosamine. The polymer has a unique behavior of fluctuating between soluble chains at pH 6 and insoluble microparticles at pH 7. The purpose of this study was to test th
Externí odkaz:
https://doaj.org/article/ef833d94069a4a87949cc4a50e2e0c88
Autor:
Ossama Nada, Anca Marian, Nicolas Tran-Khanh, Michael Buschmann, Michel Podtetenev, François Vidal, Santiago Costantino, Isabelle Brunette
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98852 (2014)
The goal of this study was to assess the effect of corneal hydration on the quality of the femtosecond laser (FSL) anterior lamellar cut. The Visumax FSL was used to dissect an 8-mm-diameter corneal flap in 22 eye bank corneas showing various levels
Externí odkaz:
https://doaj.org/article/21aa668cbb6847f9b833e916f2c39340
Autor:
Chi-Yuan Chang, Martine Bail, Nicolas Tran-Khanh, Michael D. Buschmann, Mohamad-Gabriel Alameh, Anik Chevrier, Marc Lavertu, Vincent Darras, Frédéric Lesage
Publikováno v:
Biomacromolecules. 19:112-131
Chitosan (CS) shows in vitro and in vivo efficacy for siRNA delivery but with contradictory findings for incompletely characterized systems. For understanding which parameters produce effective delivery, a library of precisely characterized chitosans
Autor:
Marc D. McKee, Valentin Nelea, Florencia Chicatun, Renny T. Franceschi, Yung-Ching Chien, Hojatollah Vali, William N. Addison, Mari T. Kaartinen, Mary M Tecklenburg, Nicolas Tran-Khanh, Showan N. Nazhat, Michael D. Buschmann
Publikováno v:
Bone. 71:244-256
Bone cell culture systems are essential tools for the study of the molecular mechanisms regulating extracellular matrix mineralization. MC3T3-E1 osteoblast cell cultures are the most commonly used in vitro model of bone matrix mineralization. Despite
Autor:
Stéphane Méthot, Michael D. Buschmann, Nicolas Tran-Khanh, Matthew S. Shive, Adele Changoor, Alberto Restrepo, Caroline D. Hoemann, William D. Stanish
Publikováno v:
Cartilage
Objective The efficacy and safety of BST-CarGel, a chitosan-based medical device for cartilage repair, was compared with microfracture alone at 1 year during a multicenter randomized controlled trial (RCT) in the knee. The quality of repair tissue of
Autor:
Gabriel N. Kaufman, Edward J. Harvey, Nicolas Tran-Khanh, Michael D. Buschmann, Huifen Wang, Alison Butler, Jan Seuntjens, Janet E. Henderson, Ailian Li, Chan Gao
Publikováno v:
Journal of Orthopaedic Research. 30:1183-1189
An overall decline in the availability of osteogenic precursor cells and growth factors in the bone marrow microenvironment have been associated with impaired bone formation and osteopenia in humans. The objective of the current study was to determin
Autor:
Nicolas Tran-Khanh, Vincent Darras, Mélina Astolfi, Marc Lavertu, Michael D. Buschmann, Marc Thibault, Abderrazzak Merzouki
Publikováno v:
Biomaterials. 32:4639-4646
The optimal ratio of the polycation's amine to DNA phosphate group (N:P) for efficient polymer-based transfection always employs excess polycation versus DNA. Most of the excess polycation remains free in solution, unassociated with the polyplexes, b
Autor:
Joshua Vorstenbosch, Kai Liu, Nicolas Tran-Khanh, Kenneth W. Finnson, Anshuman Saksena, Albane A. Bizet, Anie Philip, Michael D. Buschmann
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1813(5):742-753
Transforming growth factor-β (TGF-β) is implicated in numerous pathological disorders, including cancer and mediates a broad range of biological responses by signaling through the type I and II TGF-β receptors. Internalization of these receptors v
Autor:
Matthew S. Shive, Mark Hurtig, Michael D. Buschmann, M. Garon, Stéphane Méthot, Adele Changoor, Nicolas Tran-Khanh
Publikováno v:
Osteoarthritis and Cartilage. 19(1):126-135
Summary Objectives Collagen organization, a feature that is critical for cartilage load bearing and durability, is not adequately assessed in cartilage repair tissue by present histological scoring systems. Our objectives were to develop a new polari
Autor:
Michael D. Buschmann, Nicolas Tran-Khanh, Anik Chevrier, Caroline D. Hoemann, V. Lascau-Coman
Publikováno v:
Connective Tissue Research. 51:216-223
Primary chondrocytes cultured in agarose can escape the gel, accumulate at the interface between agarose and the culture medium, and form an outgrowing tissue. These outgrowths can appear as voluminous cartilage-like nodules that have never been prev