Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Nicolas Talarek"'
Autor:
Nikolaos Parisis, Pablo D. Dans, Muhammad Jbara, Balveer Singh, Diane Schausi-Tiffoche, Diego Molina-Serrano, Isabelle Brun-Heath, Denisa Hendrychová, Suman Kumar Maity, Diana Buitrago, Rafael Lema, Thiziri Nait Achour, Simona Giunta, Michael Girardot, Nicolas Talarek, Valérie Rofidal, Katerina Danezi, Damien Coudreuse, Marie-Noëlle Prioleau, Robert Feil, Modesto Orozco, Ashraf Brik, Pei-Yun Jenny Wu, Liliana Krasinska, Daniel Fisher
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Histone post-translational modifications promote a chromatin environment that controls transcription, DNA replication and repair, but surprisingly few phosphorylations have been documented. We report the discovery of histone H3 serine-57 pho
Externí odkaz:
https://doaj.org/article/aae698efdb56403c8aba30b80d3ec197
Autor:
Gernot Fruhmann, Christelle Marchal, Hélène Vignaud, Mathias Verduyckt, Nicolas Talarek, Claudio De Virgilio, Joris Winderickx, Christophe Cullin
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Aβ metabolism plays a pivotal role in Alzheimer’s disease. Here, we used a yeast model to monitor Aβ42 toxicity when entering the secretory pathway and demonstrate that processing in, and exit from the endoplasmic reticulum (ER) is required to un
Externí odkaz:
https://doaj.org/article/8210f0613e764d12900ed77caddc46f9
Publikováno v:
eLife, Vol 6 (2017)
How cells coordinate growth and division is key for size homeostasis. Phosphorylation by G1-CDK of Whi5/Rb inhibitors of SBF/E2F transcription factors triggers irreversible S-phase entry in yeast and metazoans, but why this occurs at a given cell siz
Externí odkaz:
https://doaj.org/article/b0b1a531221448f28f53f5713cb61bbd
Autor:
Séverine Bontron, Malika Jaquenoud, Stefania Vaga, Nicolas Talarek, Bernd Bodenmiller, Ruedi Aebersold, Claudio De Virgilio
Publikováno v:
Cell Reports, Vol 3, Iss 1, Pp 16-22 (2013)
The TORC1 and PKA protein kinases are central elements of signaling networks that regulate eukaryotic cell proliferation in response to growth factors and/or nutrients. In yeast, attenuation of signaling by these kinases following nitrogen and/or car
Externí odkaz:
https://doaj.org/article/6ca15bfa12bd47d49c2d93ac983a55cf
Autor:
Déborah Tribouillard-Tanvier, Suzana Dos Reis, Fabienne Gug, Cécile Voisset, Vincent Béringue, Raimon Sabate, Ema Kikovska, Nicolas Talarek, Stéphane Bach, Chenhui Huang, Nathalie Desban, Sven J Saupe, Surachai Supattapone, Jean-Yves Thuret, Stéphane Chédin, Didier Vilette, Hervé Galons, Suparna Sanyal, Marc Blondel
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2174 (2008)
6-Aminophenanthridine (6AP) and Guanabenz (GA, a drug currently in use for the treatment of hypertension) were isolated as antiprion drugs using a yeast-based assay. These structurally unrelated molecules are also active against mammalian prion in se
Externí odkaz:
https://doaj.org/article/a5173f705cba426cb60f9b719e0de299
Publikováno v:
Journal of visualized experiments : JoVE. (188)
Eukaryotic DNA replication is a highly regulated process that ensures that the genetic blueprint of a cell is correctly duplicated prior to chromosome segregation. As DNA synthesis defects underlie chromosome rearrangements, monitoring DNA replicatio
Publikováno v:
Journal of Visualized Experiments.
Autor:
Christelle Marchal, Claudio De Virgilio, Gernot Fruhmann, Hélène Vignaud, Joris Winderickx, Nicolas Talarek, Christophe Cullin, Mathias Verduyckt
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Frontiers Media, 2018, 11, pp.405. ⟨10.3389/fnmol.2018.00406⟩
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Frontiers Media, 2018, 11, pp.405. ⟨10.3389/fnmol.2018.00406⟩
Ab metabolism plays a pivotal role in Alzheimer’s disease. Here, we used a yeast model to monitor Aß42 toxicity when entering the secretory pathway and demonstrate that processing in, and exit from the endoplasmic reticulum (ER) is required to unl
Publikováno v:
Molecular Biology of the Cell
Molecular Biology of the Cell, American Society for Cell Biology, 2011, ⟨10.1091/mbc.E10-08-0673)⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2011, ⟨10.1091/mbc.E10-08-0673)⟩
Members of chromosome passenger complex BIR1 and SLI15 suppress the chromosome segregation defect of bub1Δ and sgo1Δ. Neither Bub1 nor Sgo1 is required for CPC activity. This study found genetic interaction between Mps1 and Sgo1. Mps1 governs local