Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Nicolas Schrantz"'
Autor:
Joanna Pawlak, Benjamin F. Cravatt, Kim Masuda, Stefan Freigang, Yang Liu, Victoria Zadorozhny, Lisa Kain, Rana Herro, Nicolas Schrantz, Philippe Krebs, Paul B. Savage, Luc Teyton, Michele K. McKinney, Albert Bendelac
Publikováno v:
Journal of Clinical Investigation
The Journal of clinical investigation
The Journal of clinical investigation
The potent regulatory properties of NKT cells render this subset of lipid-specific T cells a promising target for immunotherapeutic interventions. The marine sponge glycolipid alpha-galactosylceramide (alphaGalCer) is the proto-typic NKT cell agonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da36076fa5337f15b91aef180cea7010
https://doi.org/10.1172/jci40451
https://doi.org/10.1172/jci40451
Autor:
Carlos Cantu, Yun Ping Wu, Dapeng Zhou, Ying Gao, Yuval Sagiv, Kelly Hudspeth, Dacheng Wang, Luc Teyton, Paul B. Savage, Steven B. Levery, Susann Teneberg, Tadashi Yamashita, Albert Bendelac, Ning Yin, Jochen Mattner, Nicolas Schrantz, Richard L. Proia
Publikováno v:
Science. 306:1786-1789
NKT cells represent a distinct lineage of T cells that coexpress a conserved αβ T cell receptor (TCR) and natural killer (NK) receptors. Although the TCR of NKT cells is characteristically autoreactive to CD1d, a lipid-presenting molecule, endogeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127f416397d8fc793e4dfb7911864f41
https://doi.org/10.1126/science.1103440
https://doi.org/10.1126/science.1103440
Autor:
Xiaoyang Qi, Paul B. Savage, Luc Teyton, Don J. Mahuran, Carlos Cantu, Kamel Benlagha, Nicolas Schrantz, Carlos R. Morales, Gregory A. Grabowski, Ashok B. Kulkarni, Albert Bendelac, Yuval Sagiv, Dapeng Zhou
Publikováno v:
Science. 303:523-527
It is now established that CD1 molecules present lipid antigens to T cells, although it is not clear how the exchange of lipids between membrane compartments and the CD1 binding groove is assisted. We report that mice deficient in prosaposin, the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2071fc9986a6401a254cad38c61bc18
https://doi.org/10.1126/science.1092009
https://doi.org/10.1126/science.1092009
Autor:
Odile Ducrey, Richard J. Ulevitch, Jean da Silva Correia, Jongdae Lee, Ken Nomoto, M. Germana Sanna, Quinn Deveraux, Nicolas Schrantz
Publikováno v:
Molecular and Cellular Biology. 22:1754-1766
The antiapoptotic properties of the inhibitor of apoptosis (IAP) family of proteins have been linked to caspase inhibition. We have previously described an alternative mechanism of XIAP inhibition of apoptosis that depends on the selective activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe9e7da63503e55e062526f21c9cae5d
https://doi.org/10.1128/mcb.22.6.1754-1766.2002
https://doi.org/10.1128/mcb.22.6.1754-1766.2002
Autor:
Surendra Sharma, Aimé Vazquez, Nicolas Schrantz, Gérald Leca, Shahul Mouhamad, Marie-Françoise Bourgeade
Publikováno v:
Molecular Biology of the Cell. 12:3139-3151
On binding to its receptor, transforming growth factor beta (TGFbeta) induces apoptosis in a variety of cells, including human B lymphocytes. We have previously reported that TGFbeta-mediated apoptosis is caspase-dependent and associated with activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4f720a45e64eb70c70ebaa0b94abac
https://doi.org/10.1091/mbc.12.10.3139
https://doi.org/10.1091/mbc.12.10.3139
Autor:
Laurence Besnault, Marie-Françoise Bourgeade, Nicolas Schrantz, Marie-Thérèse Auffredou, Aimé Vazquez, Gérald Leca
Publikováno v:
Cell Death & Differentiation. 8:152-161
Divalent cations, including Zinc and Manganese ions, are important modulators of cell activation. We investigated the ability of these two divalent cations to modulate apoptosis in human Burkitt lymphoma B cells line (Ramos). We found that Zinc (from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1737b8c95d32caa43bb3c51881b7f06a
https://doi.org/10.1038/sj.cdd.4400772
https://doi.org/10.1038/sj.cdd.4400772
Autor:
Nicolas Schrantz, Marie-Thérèse Auffredou, Aimé Vazquez, Gérald Leca, Françoise Mitenne, Dominique Blanchard
Publikováno v:
Cell Death & Differentiation. 6:445-453
Manganese ions block apoptosis of phagocytes induced by various agents. The prevention of apoptosis was attributed to the activation of manganous superoxide dismutase (Mn-SOD) and to the antioxidant function of free Mn2+ cations. However, the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf0fb7a3a3ff2616b8bd1068fb1205d
https://doi.org/10.1038/sj.cdd.4400508
https://doi.org/10.1038/sj.cdd.4400508
Autor:
Natasha Del Cid, Dariusz T Stepniak, Allison Ferrer, Brad Scott, Jonathan Magana, Xiaoxiao Li, Lisa Ma, Cherlyn Miranda, Shourong Li, Nicolas Schrantz, Qiulong Huang, Sara Becker-Catania, Castle J Funatake, Peggy Just
Publikováno v:
The Journal of Immunology. 196:201.6-201.6
We have developed flow cytometry antibodies against three molecules expressed on tissue-resident mouse macrophages: MerTK, GPNMB (aka Osteoactivin, DC-HIL), and VSIG4 (aka CRIg). MerTK, a receptor tyrosine kinase, plays a crucial role in the clearanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ec4455388cae85846b2f2c0a4c3288a
https://doi.org/10.4049/jimmunol.196.supp.201.6
https://doi.org/10.4049/jimmunol.196.supp.201.6
Autor:
Sharon Lu, Jun-Eui Park, Paul B. Chapman, Maria J. Prendes, Govind Ragupathi, Nicolas Schrantz, Dianna Y. Wu
GD3, a ganglioside expressed on melanoma, is the only tumour-associated glycolipid described to date that can induce a CD1d-restricted natural killer T (NKT)-cell response. We analysed the fine specificity of GD3-reactive NKT cells and discovered tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2593367e02ab3a7144b758a46a5f4770
https://europepmc.org/articles/PMC2433273/
https://europepmc.org/articles/PMC2433273/
Autor:
Dariusz Stepniak, Brandi Atteberry, Shourong Li, Oscar Baterina, Natalie Oxford, Cherlyn Miranda, Ana Miletic, Nicolas Schrantz, Qiulong Huang, Castle Funatake, Margaret Just
Publikováno v:
The Journal of Immunology. 194:55.13-55.13
Mer is a member of the TAM family of tyrosine kinase receptors that also includes Axl and Tyro3. Mer is expressed on a subset of anti-inflammatory macrophages and is involved in the removal of apoptotic cells. The engulfment of apoptotic cells relies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83aebd412ede4518fba725905b06b3fb
https://doi.org/10.4049/jimmunol.194.supp.55.13
https://doi.org/10.4049/jimmunol.194.supp.55.13