Challenges in molecular diagnosis of multiple endocrine neoplasia

Autor: Pauline Romanet, Théo Charnay, Nicolas Sahakian, Thomas Cuny, Frédéric Castinetti, Anne Barlier

Publikováno v: Frontiers in Endocrinology, Vol 15 (2024)

Multiple endocrine neoplasia (MEN) is a group of rare genetic diseases characterized by the occurrence of multiple tumors of the endocrine system in the same patient. The first MEN described was MEN1, followed by MEN2A, and MEN2B. The identification

Externí odkaz: https://doaj.org/article/1277a13189b349e98386e7e84811419a

Real-life clinical impact of a five-tiered classification of pituitary tumors

Autor: Nicolas Sahakian, Romain Appay, Noémie Resseguier, Thomas Graillon, Cécilia Piazzola, Cécilia Laure, Dominique Figarella-Branger, Jean Régis, Frédéric Castinetti, Thierry Brue, Henry Dufour, Thomas Cuny

Publikováno v: European Journal of Endocrinology
European Journal of Endocrinology, 2022, 187 (6), pp.893-904. ⟨10.1530/EJE-22-0812⟩

Introduction Usually benign, pituitary tumors (PT) can be invasive and aggressive with a propensity to progress and/or recur. Trouillas's clinicopathological classification attempts to predict the evolutionary risk of a PT. In this study, we assessed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f5c0df3baef3c5265bfc2b24141e3d
https://doi.org/10.1530/eje-22-0812

18F-DOPA PET/CT at the Forefront of Initial or Presurgical Evaluation of Small-Intestine Neuroendocrine Tumors

Autor: Eric Ouvrard, Louis De Mestier, Caroline Boursier, Boumediene Lachachi, Nicolas Sahakian, Elodie Chevalier, Nidaa Mikail, Josefina Carullo, Aurélie Bando-Delaunay, Thomas Walter, Gabriel G. Malouf, Pietro Addeo, Gilles Poncet, Frederic Sebag, Rachida Lebtahi, Bernard Goichot, David Taïeb, Alessio Imperiale

Publikováno v: Journal of Nuclear Medicine. 63:1865-1870

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f60e8ae18ff51358de62c22601beb3a7
https://doi.org/10.2967/jnumed.122.263984

SGLT2 inhibitors as potentially helpful drugs in PI3K inhibitor-induced diabetes: a case report

Autor: Pascale Silvestre-Aillaud, René Valéro, Sophie Béliard, Lauranne Cattieuw, Nicolas Sahakian, Clotilde Ramillon-Cury, Audrey Bégu-Le Corroller

Publikováno v: Clinical Diabetes and Endocrinology
Clinical Diabetes and Endocrinology, 2021, 7 (1), pp.17. ⟨10.1186/s40842-021-00125-8⟩
Clinical Diabetes and Endocrinology, Vol 7, Iss 1, Pp 1-4 (2021)

Background Hyperglycemia is the most common side-effect of phosphatidylinositol 3-kinase (PI3K) inhibitors that are approved for the treatment of some advanced or metastatic breast cancers. This side-effect is likely due to the central role of PI3K i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4227aa1a4f2113b544efe21581e9472f
https://hal-amu.archives-ouvertes.fr/hal-03653403

Risk stratification of adrenal masses by [ 18 F]FDG PET/CT: Changing tactics

Autor: Anderson Loundou, Frederic Castinetti, Carole Guerin, Jean-Christophe Lifante, Eric Mirallié, Betty Salgues, Karine Baumstarck, Frederic Sebag, Nicolas Sahakian, Vincent Amodru, Laurent Brunaud, David Taïeb, François Pattou

Publikováno v: Clinical Endocrinology
Clinical Endocrinology, 2021, 94 (2), pp.133-140. ⟨10.1111/cen.14338⟩
Clinical Endocrinology, Wiley, 2021, 94 (2), pp.133-140. ⟨10.1111/cen.14338⟩

Context [18 F]FDG PET/CT improves adrenal tumour characterization. However, there is still no consensus regarding the optimal imaging biomarkers of malignancy. Objectives To assess the performance of Tumour standardized uptake value (SUV)max :Liver S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf4add861326c8abc8a1de60e64b1f2
https://hal.science/hal-03363919