Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Nicolas Riteau"'
Autor:
Mégane Nascimento, Sarah Huot-Marchand, Manoussa Fanny, Marjolène Straube, Marc Le Bert, Florence Savigny, Lionel Apetoh, Jacques Van Snick, Fabrice Trovero, Mathias Chamaillard, Valérie F. J. Quesniaux, Bernhard Ryffel, Philippe Gosset, Aurélie Gombault, Nicolas Riteau, Harry Sokol, Isabelle Couillin
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Chronic obstructive pulmonary disease (COPD) is a major health issue primarily caused by cigarette smoke (CS) and characterized by breathlessness and repeated airway inflammation. NLRP6 is a cytosolic innate receptor controlling intestinal inflammati
Externí odkaz:
https://doaj.org/article/a7d159a73b8e40fbaeb58a9775e4aac6
Autor:
Sandra Carignon, Dorian De Moura Rodrigues, David Gosset, Elodie Culerier, Sarah Huot-Marchand, Florence Savigny, Eric Kaya, Valerie Quesniaux, Aurélie Gombault, Isabelle Couillin, Bernhard Ryffel, Marc Le Bert, Nicolas Riteau
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe pathogenesis of chronic lung diseases is multifaceted with a major role of recurrent micro-injuries of the epithelium. While several reports clearly indicated a prominent role for surfactant-producing alveolar epithelial type 2 (AT2)
Externí odkaz:
https://doaj.org/article/71754b8105ab4c509c24ac5dfc6cb235
Autor:
Sarah Huot-Marchand, Mégane Nascimento, Elodie Culerier, Mélissa Bourenane, Florence Savigny, Corinne Panek, Cindy Serdjebi, Marc Le Bert, Valérie F. J. Quesniaux, Bernhard Ryffel, Petr Broz, Nicolas Riteau, Aurélie Gombault, Isabelle Couillin
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chronic pulmonary inflammation and chronic obstructive pulmonary disease (COPD) are major health issues largely due to air pollution and cigarette smoke (CS) exposure. The role of the innate receptor NLRP3 (nucleotide-binding domain and leucine-rich
Externí odkaz:
https://doaj.org/article/6d26fc733ad047d9ac5a9f202429cc1e
Autor:
Isabelle Couillin, Nicolas Riteau
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Innate immunity is regulated by a broad set of evolutionary conserved receptors to finely probe the local environment and maintain host integrity. Besides pathogen recognition through conserved motifs, several of these receptors also sense aberrant o
Externí odkaz:
https://doaj.org/article/5ff4baa8334c4009a6c672c486e2b5d3
Publikováno v:
Cells, Vol 11, Iss 21, p 3483 (2022)
The cGAS–STING pathway displays important functions in the regulation of innate and adaptive immunity following the detection of microbial and host-derived DNA. Here, we briefly summarize biological functions of STING and review recent literature h
Externí odkaz:
https://doaj.org/article/c375d078fcd7431a9e9616c8784f1332
Autor:
Mégane Nascimento, Aurélie Gombault, Norinne Lacerda-Queiroz, Corinne Panek, Florence Savigny, Malak Sbeity, Manon Bourinet, Marc Le Bert, Nicolas Riteau, Bernhard Ryffel, Valérie F. J. Quesniaux, Isabelle Couillin
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Cigarette smoke exposure is a leading cause of chronic obstructive pulmonary disease (COPD), a major health issue characterized by airway inflammation with fibrosis and emphysema. Here we demonstrate that acute exposure to cigarette smoke ca
Externí odkaz:
https://doaj.org/article/cb153acec13d4224a9663929f0a27175
Autor:
Florence Savigny, Corinne Schricke, Norinne Lacerda-Queiroz, Mélanie Meda, Mégane Nascimento, Sarah Huot-Marchand, Felipe Da Gama Monteiro, Bernhard Ryffel, Aurélie Gombault, Marc Le Bert, Isabelle Couillin, Nicolas Riteau
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Idiopathic pulmonary fibrosis (IPF) is the most common and severe type of interstitial lung disease for which current treatments display limited efficacy. IPF is largely driven by host-derived danger signals released upon recurrent local tissue damag
Externí odkaz:
https://doaj.org/article/389163174a7f427fb322494692ab58d4
Autor:
Mégane Nascimento, Sarah Huot-Marchand, Aurélie Gombault, Corinne Panek, Manon Bourinet, Manoussa Fanny, Florence Savigny, Pascal Schneider, Marc Le Bert, Bernhard Ryffel, Nicolas Riteau, Valérie F. J. Quesniaux, Isabelle Couillin
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Cigarette smoke (CS) is the major cause of chronic lung injuries, such as chronic obstructive pulmonary disease (COPD). In patients with severe COPD, tertiary lymphoid follicles containing B lymphocytes and B cell-activating factor (BAFF) overexpress
Externí odkaz:
https://doaj.org/article/729c1d3af59445de98d9a2038cc29a77
Autor:
Manoussa Fanny, Mégane Nascimento, Ludivine Baron, Corinne Schricke, Isabelle Maillet, Myriam Akbal, Nicolas Riteau, Marc Le Bert, Valérie Quesniaux, Bernhard Ryffel, Aurélie Gombault, Sandra Même, William Même, Isabelle Couillin
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Idiopathic pulmonary fibrosis is a progressive, devastating, and yet untreatable fibrotic disease of unknown origin. Interleukin-33 (IL-33), an IL-1 family member acts as an alarmin with pro-inflammatory properties when released after stress or cell
Externí odkaz:
https://doaj.org/article/bc689d56917a4d94a76626b634752a47
Autor:
Eduardo P. Amaral, Nicolas Riteau, Mahtab Moayeri, Nolan Maier, Katrin D. Mayer-Barber, Rosana M. Pereira, Silvia L. Lage, Andre Kubler, William R. Bishai, Maria R. D’Império-Lima, Alan Sher, Bruno B. Andrade
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Lysosomal cathepsin B (CTSB) has been proposed to play a role in the induction of acute inflammation. We hypothesised that the presence of active CTSB in the cytosol is crucial for NLRP3-inflammasome assembly and, consequently, for mature IL-1β gene
Externí odkaz:
https://doaj.org/article/05a9b43a81de41989607b87fe438516b