Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nicolas Pleche"'
Autor:
Giovanni Magistrelli, Guillemette Pontini, Yves Poitevin, Pauline Malinge, Jérémie Bourguignon, Florence Gauye, Elise Fleury, Nicolas Plèche, Lydia Galissaires, Nicolas Fischer
Publikováno v:
Antibodies, Vol 7, Iss 3, p 29 (2018)
Bispecific antibodies (bsAbs) are often composed of several polypeptide chains that have to be expressed adequately to enable optimal assembly and yield of the bsAb. κλ bodies are a bispecific format with a native IgG structure, composed of two dif
Externí odkaz:
https://doaj.org/article/3190ff1b9542462b83d6255b1fa429d0
Autor:
Anja Seckinger, Sara Majocchi, Valéry Moine, Lise Nouveau, Hoang Ngoc, Bruno Daubeuf, Ulla Ravn, Nicolas Pleche, Sebastien Calloud, Lucile Broyer, Laura Cons, Adeline Lesnier, Laurence Chatel, Anne Papaioannou, Susana Salgado-Pires, Sebastian Krämer, Ines Gockel, Florian Lordick, Krzysztof Masternak, Yves Poitevin, Giovanni Magistrelli, Pauline Malinge, Limin Shang, Sonja Kallendrusch, Klaus Strein, Dirk Hose
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-23 (2023)
Abstract Background T-cell retargeting to eliminate CEACAM5-expressing cancer cells via CEACAM5xCD3 bispecific antibodies (BsAbs) showed limited clinical activity so far, mostly due to insufficient T-cell activation, dose-limiting toxicities, and for
Externí odkaz:
https://doaj.org/article/30b29a2c343143119fd06970474edb47
Autor:
Laurence Chatel, Nicolas Pleche, Guillemette Pontini, Vanessa Buatois, Laura Cons, Lise Nouveau, Walter Ferlin
Publikováno v:
European Journal of Immunology
The aberrant release of inflammatory mediators often referred to as a cytokine storm or cytokine release syndrome (CRS), is a common and sometimes fatal complication in acute infectious diseases including Ebola, dengue, COVID‐19, and influenza. Fat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a107de6a81cee45b94f71ba4d12a1401
https://doi.org/10.1002/eji.202149181
https://doi.org/10.1002/eji.202149181
Autor:
Sara Majocchi, Pauline Lloveras, Coline Burnet-Merlin, Lise Nouveau, Nicolas Pleche, Pauline Malinge, Claudia Batista, Christelle Daviet, Maud Charreton, Guillemette Pontini, Franck Gueneau, Valery Moine, Giovanni Magistrelli, Limin Shang, Walter Ferlin, Krzysztof Masternak
Publikováno v:
Cancer Research. 82:2884-2884
Tumor-targeted CD28 bispecific antibodies (bsAbs) are designed to co-stimulate T cells specifically within the tumor microenvironment. By bridging T cells to malignant cells expressing a selected tumor-associated antigen (TAA), CD28 bsAbs deliver the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c8c4fcb60509ec214aee6203658b67e
https://doi.org/10.1158/1538-7445.am2022-2884
https://doi.org/10.1158/1538-7445.am2022-2884
Autor:
Xavier Chauchet, Sébastien Calloud, Margaux Legrand, Laura Cons, Laurence Chatel, Pauline Lloveras, Coline Burnet-Merlin, Louis Hellequin, Nicolas Bosson, Pauline Malinge, Nicolas Pleche, Jérémie Bourguignon, Guillemette Pontini, Christophe Guillamo, Ulla Ravn, Valéry Moine, Bruno Daubeuf, Yves Poitevin, Giovanni Magistrelli, Limin Shang, Walter Ferlin, Krzysztof Masternak
Publikováno v:
Cancer Research. 82:3428-3428
Blocking the CD47/SIRPα checkpoint has recently emerged as an effective approach to mobilize the myeloid cell compartment and to improve antitumor responses in the clinic. Preclinical models have demonstrated the synergistic benefit of combined CD47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e386a4493f9b75447a37e12584347a0d
https://doi.org/10.1158/1538-7445.am2022-3428
https://doi.org/10.1158/1538-7445.am2022-3428
Autor:
Nicolas Pleche, Lydia Galissaires, Elise Fleury, Jérémie Bourguignon, Pauline Malinge, Yves Poitevin, Nicolas Fischer, Guillemette Pontini, Florence Gauye, Giovanni Magistrelli
Publikováno v:
Antibodies
Volume 7
Issue 3
Antibodies, Vol 7, Iss 3, p 29 (2018)
Volume 7
Issue 3
Antibodies, Vol 7, Iss 3, p 29 (2018)
Bispecific antibodies (bsAbs) are often composed of several polypeptide chains that have to be expressed adequately to enable optimal assembly and yield of the bsAb. &kappa
&lambda
bodies are a bispecific format with a native IgG structure,
&lambda
bodies are a bispecific format with a native IgG structure,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed9a98fb12ff80caa7341257dc15576a
Autor:
Amandine Gautier-Stein, Sylvie Casteras, Jean-André Tourette, Carine Zitoun, Blandine Gri, Maud Soty, Caroline Romestaing, Aya Abdul-Wahed, Anne Sardella, Nicolas Pleche, Gilles Mithieux, Fabienne Rajas, Damien Roussel, Hervé Guillou
Publikováno v:
Molecular metabolism
Molecular metabolism, Elsevier, 2014, 3 (5), pp.531-543. ⟨10.1016/j.molmet.2014.05.005⟩
Molecular metabolism, Elsevier, 2014, 3, pp.531-543. ⟨10.1016/j.molmet.2014.05.005⟩
Molecular Metabolism 5 (3), 531-543. (2014)
Molecular Metabolism
Molecular metabolism, 2014, 3 (5), pp.531-543. ⟨10.1016/j.molmet.2014.05.005⟩
Molecular metabolism, Elsevier, 2014, 3 (5), pp.531-543. ⟨10.1016/j.molmet.2014.05.005⟩
Molecular metabolism, Elsevier, 2014, 3, pp.531-543. ⟨10.1016/j.molmet.2014.05.005⟩
Molecular Metabolism 5 (3), 531-543. (2014)
Molecular Metabolism
Molecular metabolism, 2014, 3 (5), pp.531-543. ⟨10.1016/j.molmet.2014.05.005⟩
International audience; ABSTRACTType 2 diabetes is characterized by a deterioration of glucose tolerance, which associates insulinresistance of glucose uptake by peripheral tissues and increased endogenous glucose production.Here we report that the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382989fb23bedbed0186eb749c1da2c0
https://www.hal.inserm.fr/inserm-01350728
https://www.hal.inserm.fr/inserm-01350728
