Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nicolas Piganeau"'
Autor:
Günter Mayer, Katja Eydeler, Inken Lorenzen, Cindy Meyer, Joachim Grötzinger, Tijana Zivkovic, Nicolas Piganeau, Stefan Rose-John, Eileen Magbanua, Ulrich Hahn
Publikováno v:
RNA Biology
Aptamers represent an emerging strategy to deliver cargo molecules, including dyes, drugs, proteins or even genes, into specific target cells. Upon binding to specific cell surface receptors aptamers can be internalized, for example by macropinocytos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b428b6b20b13eb8d41ee01ade67957
https://doi.org/10.4161/rna.9.1.18062
https://doi.org/10.4161/rna.9.1.18062
Autor:
Christian Betzel, María A. Chávez, Markus Perbandt, Patrick Ziegelmüller, Rossana García-Fernández, Nicolas Piganeau, Ulrich Hahn, Lars Redecke, Dirk Rehders
Publikováno v:
The Journal of biological chemistry. 290(22)
Elastase-like enzymes are involved in important diseases such as acute pancreatitis, chronic inflammatory lung diseases, and cancer. Structural insights into their interaction with specific inhibitors will contribute to the development of novel anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ecc4c0c5a19649008ed02f93de4ada
https://pubmed.ncbi.nlm.nih.gov/25878249
https://pubmed.ncbi.nlm.nih.gov/25878249
Publikováno v:
Journal of Molecular Biology. 312:1177-1190
In vitro selection techniques offer powerful and versatile methods to isolate nucleic acid sequences with specific activities from huge libraries. We describe an in vitro selection strategy for the de novo selection of allosteric self-cleaving ribozy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::804bf6b6956b131c7ef431c08f692e78
https://doi.org/10.1006/jmbi.2001.4981
https://doi.org/10.1006/jmbi.2001.4981
Autor:
Jörg S. Hartig, Dmitry A. Samarsky, Andreas Tauer, Michael R. Green, Michael Famulok, Nicolas Piganeau, Julian Davies, Andreas Jenne
Publikováno v:
Nature Biotechnology. 19:56-61
The ability to rapidly identify small molecules that interact with RNA would have significant clinical and research applications. Low-molecular-weight molecules that bind to RNA have the potential to be used as drugs. Therefore, technologies facilita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca32fbc5fee5794df85664085d4698d5
https://doi.org/10.1038/83513
https://doi.org/10.1038/83513
Publikováno v:
Angewandte Chemie. 112:4538-4542
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b872dd9e05b5153743bed910229c984
https://doi.org/10.1002/1521-3757(20001201)112:23<4538::aid-ange4538>3.0.co
https://doi.org/10.1002/1521-3757(20001201)112:23<4538::aid-ange4538>3.0.co
Publikováno v:
Angewandte Chemie. 39:4369-4373
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcfabd752af56d384557ec69e5942675
https://doi.org/10.1002/1521-3773(20001201)39:23<4369::aid-anie4369>3.0.co
https://doi.org/10.1002/1521-3773(20001201)39:23<4369::aid-anie4369>3.0.co
Publikováno v:
RNA biology. 9(4)
In bacteria, adaptive response to external stimuli is often regulated by small RNAs (sRNAs). In Escherichia coli, the organism in which sRNAs have been best characterized so far, no function could be attributed to 40 out of 79 sRNAs. Here we decipher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37640215a79b7f6c5ae4be751c0556a9
https://pubmed.ncbi.nlm.nih.gov/22336764
https://pubmed.ncbi.nlm.nih.gov/22336764
Autor:
Nicolas, Piganeau
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 848
Allosteric ribozymes can be designed to respond to virtually any molecule of choice. The resulting species may be used for example as synthetic regulators of gene expression or alternatively as biosensors. In vitro selection techniques allow the isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4187ac2b16a7804632a5c973638b112
https://pubmed.ncbi.nlm.nih.gov/22315077
https://pubmed.ncbi.nlm.nih.gov/22315077
Autor:
Nicolas Piganeau
Publikováno v:
Methods in Molecular Biology ISBN: 9781617795442
Allosteric ribozymes can be designed to respond to virtually any molecule of choice. The resulting species may be used for example as synthetic regulators of gene expression or alternatively as biosensors. In vitro selection techniques allow the isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f705420035f99d1ae80c78c8091b4d09
https://doi.org/10.1007/978-1-61779-545-9_19
https://doi.org/10.1007/978-1-61779-545-9_19
Autor:
Nicolas, Piganeau
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 535
In vitro selection techniques offer powerful and versatile methods to isolate nucleic acid sequences with specific activities from huge libraries. The present protocol describes an in vitro selection strategy for the de novo selection of allosteric s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2f3934677c41e062cfe35d2a6173cc7
https://pubmed.ncbi.nlm.nih.gov/19377981
https://pubmed.ncbi.nlm.nih.gov/19377981