Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nicolas Perrière"'
Autor:
Huilong Luo, Bruno Saubamea, Stéphanie Chasseigneaux, Véronique Cochois, Maria Smirnova, Fabienne Glacial, Nicolas Perrière, Catarina Chaves, Salvatore Cisternino, Xavier Declèves
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Transient receptor potential vanilloid 1-4 (TRPV1-4) expression and functionality were investigated in brain microvessel endothelial cells (BMEC) forming the blood–brain barrier (BBB) from rat and human origins. In rat, Trpv1-4 were detected by qRT
Externí odkaz:
https://doaj.org/article/f367cf1943ff4c6e91196b4b2b382f4f
Autor:
Catarina Chaves, Federica Campanelli, Hélène Chapy, David Gomez-Zepeda, Fabienne Glacial, Maria Smirnova, Meryam Taghi, Johan Pallud, Nicolas Perrière, Xavier Declèves, Marie-Claude Menet, Salvatore Cisternino
Publikováno v:
Pharmaceutics, Vol 12, Iss 4, p 308 (2020)
Organic cation transporters (OCTs) participate in the handling of compounds in kidneys and at the synaptic cleft. Their role at the blood-brain barrier (BBB) in brain drug delivery is still unclear. The presence of OCT1,2,3 (SLC22A1-3) in mouse, rat
Externí odkaz:
https://doaj.org/article/c2afaafc389e4db8b9cc11af61128488
Autor:
David Gomez-Zepeda, Nicolas Perrière, Fabienne Glacial, Meryam Taghi, Cérina Chhuon, Jean-Michel Scherrmann, Philippe Sergent, Amélie Moreau, Claire Denizot, Yannick Parmentier, Salvatore Cisternino, Xavier Decleves, Marie-Claude Menet
Publikováno v:
Toxicology and Applied Pharmacology. 465:116456
Autor:
Nicolas Perrière, Bruno Saubaméa, Sandrine Bourdoulous, David M. Smadja, Stéphanie Chasseigneaux, Huilong Luo, Véronique Cochois, Nina Choublier, Elisa Rossi, Pierre-Olivier Couraud, Maria Smirnova, Xavier Declèves, Salvatore Cisternino, Fabienne Glacial, Marie-Claude Menet
Publikováno v:
Molecular Pharmaceutics
Molecular Pharmaceutics, American Chemical Society, 2019, ⟨10.1021/acs.molpharmaceut.8b01252⟩
Molecular Pharmaceutics, American Chemical Society, 2019, ⟨10.1021/acs.molpharmaceut.8b01252⟩
International audience; The effect of cannabidiol (CBD), a high-affinity agonist of the transient receptor potential vanilloid-2 (TRPV2) channel, has been poorly investigated in human brain microvessel endothelial cells (BMEC) forming the blood−bra
Autor:
Jean-François Ghersi-Egea, Mathieu Santin, Christiane Charriaut-Marlangue, Mickael Tanter, Fabienne Glacial, Luigi Titomanlio, Stéphane Lehéricy, Zsolt Csaba, Charlie Demene, Pierre-Louis Leger, Pascal Dournaud, Bérard Coqueran, Stéphane Auvin, Iolanda Parente, Alice Jacquens, Isabelle Margaill, Homa Adle-Biassette, Jean-François Aubry, Pierre Gressens, Charlotte Constans, Nicolas Perrière, Tania Vitalis
Publikováno v:
Neuropathology and Applied Neurobiology
Neuropathology and Applied Neurobiology, 2021, 47 (2), pp.297-315. ⟨10.1111/nan.12665⟩
Neuropathology and Applied Neurobiology, 2021, 47 (2), pp.297-315. ⟨10.1111/nan.12665⟩
We introduce a novel approach based on agonist‐induced internalization of a neuronal G protein‐coupled receptor widely distributed in the mammalian brain, the somatostatin receptor type 2 (SST2).This approach provides an alternative and simple ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03cf08e65f5f6f615d024a87931ccdae
https://hal.science/hal-03818501
https://hal.science/hal-03818501
Autor:
Xavier Declèves, Joël Poupon, Xi Tan, Huilong Luo, Matthieu Gauthier, Frank Bellivier, Fabien Gosselet, Nicolas Perrière, Marie-Pierre Dehouck, Christophe Landry, Salvatore Cisternino
Publikováno v:
Molecular Pharmaceutics
Molecular Pharmaceutics, American Chemical Society, 2018, 15 (7), pp.2528-2538. ⟨10.1021/acs.molpharmaceut.8b00018⟩
Molecular Pharmaceutics, American Chemical Society, 2018, 15 (7), pp.2528-2538. ⟨10.1021/acs.molpharmaceut.8b00018⟩
International audience; Variability in drug response to lithium (Li+) is poorly understood and significant, as only 40% of patients with bipolar disorder highly respond to Li+. Li+ can be transported by sodium (Na+) transporters in kidney tubules or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea44086c5228644a449bf9342f12c04
https://hal-univ-artois.archives-ouvertes.fr/hal-02506165
https://hal-univ-artois.archives-ouvertes.fr/hal-02506165
A functional in vitro model of rat blood–brain barrier for molecular analysis of efflux transporters
Autor:
Salah Yousif, Xavier Declèves, Sylvie Cazaubon, Nicolas Perrière, Tetsuya Terasaki, Fanchon Bourasset, Mária A. Deli, Jean Michel Scherrmann, Pierre-Olivier Couraud, Nathalie Chaverot, Satoko Hori, Françoise Roux, Salvatore Cisternino, Jamal Temsamani
Publikováno v:
Brain Research. 1150:1-13
Physiological studies of the blood–brain barrier (BBB) are often performed in rats. We describe the functional characterization of a reproducible in vitro model of the rat BBB and its validation for investigating mechanisms involved in BBB regulati
Autor:
Fabienne Glacial, Nicolas Perrière, Catherine Driancourt, Oriane Guillevic, Julie Boyer-Di Ponio, Fida El-Ayoubi, Maeva Godet, Pierre Olivier Couraud, Kayathiri Ganeshamoorthy, Georges Uzan
Publikováno v:
PLoS ONE
PLoS ONE, 2014, 9 (1), pp.e84179. ⟨10.1371/journal.pone.0084179⟩
PLoS ONE, Vol 9, Iss 1, p e84179 (2014)
PLoS ONE, Public Library of Science, 2014, 9 (1), pp.e84179. 〈10.1371/journal.pone.0084179〉
PLoS ONE, Public Library of Science, 2014, 9 (1), pp.e84179. ⟨10.1371/journal.pone.0084179⟩
PLoS ONE, 2014, 9 (1), pp.e84179. ⟨10.1371/journal.pone.0084179⟩
PLoS ONE, Vol 9, Iss 1, p e84179 (2014)
PLoS ONE, Public Library of Science, 2014, 9 (1), pp.e84179. 〈10.1371/journal.pone.0084179〉
PLoS ONE, Public Library of Science, 2014, 9 (1), pp.e84179. ⟨10.1371/journal.pone.0084179⟩
International audience; OBJECTIVE: The vascular system is adapted to specific functions in different tissues and organs. Vascular endothelial cells are important elements of this adaptation, leading to the concept of 'specialized endothelial cells'.
Autor:
Jean-Marc Alessandri, Monique Lavialle, Françoise Roux, Stephen C. Cunnane, Nicolas Perrière, Mélanie Jouin, Bénédicte Langelier, Fabien Pifferi, Philippe Guesnet
Publikováno v:
Neurochemistry International
Neurochemistry International, Elsevier, 2010, 56 (5), pp.703-710. ⟨10.1016/j.neuint.2010.02.006⟩
Neurochemistry International, 2010, 56 (5), pp.703-710. ⟨10.1016/j.neuint.2010.02.006⟩
Neurochemistry International, Elsevier, 2010, 56 (5), pp.703-710. ⟨10.1016/j.neuint.2010.02.006⟩
Neurochemistry International, 2010, 56 (5), pp.703-710. ⟨10.1016/j.neuint.2010.02.006⟩
Several in vivo studies suggest that docosahexaenoic acid (22:6 n -3), the main n -3 long-chain polyunsaturated fatty acids (LC-PUFA) of brain membranes, could be an important regulator of brain energy metabolism by affecting glucose utilization and
Autor:
Hervé Enslen, Pedro Viegas, Nicolas Perrière, Sylvie Cazaubon, Nathalie Chaverot, Pierre-Olivier Couraud
Publikováno v:
Journal of cell science. 119(Pt 22)
The conversion of prion protein (PrP(C)) to its protease-resistant isoform is involved in the pathogenesis of prion diseases. Although PrP(C) is highly expressed in neurons and other cell types, its physiological function still remains elusive. Here,