Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Nicolas Pelisch"'
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-16 (2020)
Abstract Background Secondary damage after spinal cord injury (SCI) is characterized by a cascade of events including hemorrhage, apoptosis, oxidative stress, and inflammation which increase the lesion size which can influence the functional impairme
Externí odkaz:
https://doaj.org/article/a70ab5f2a1cd420dbbd6f04516acaa5b
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/75ff1f186c0340a3ad63364dafdcb028
Publikováno v:
Neurobiology of Disease, Vol 106, Iss , Pp 235-243 (2017)
Severed CNS axons often retract or dieback away from the injury site and fail to regenerate. The precise mechanisms underlying acute axonal dieback and secondary axonal degeneration remain poorly understood. Here we investigate the role of Ca2+ store
Externí odkaz:
https://doaj.org/article/0c6d342c1e2c4795b1cfcb170e1d9b9a
Autor:
Shinji Kosaka, Nicolas Pelisch, Matlubur Rahman, Daisuke Nakano, Hirofumi Hitomi, Hiroyuki Kobori, Noriyasu Fukuoka, Hideki Kobara, Hirohito Mori, Tsutomu Masaki, Ludek Cervenka, Yasuo Matsumura, Hitoshi Houchi, Akira Nishiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 121, Iss 2, Pp 95-102 (2013)
We examined the effects of angiotensin II AT1–receptor blockade with olmesartan on high fat (HF) diet–induced vascular oxidative stress and endothelial dysfunction in normal salt (NS) diet–fed Dahl salt-sensitive (DSS) rats. Treatment with NS +
Externí odkaz:
https://doaj.org/article/4910e0eadf544ef09c1413e049a4e8f2
Autor:
Keisuke Ohnishi, Miki Murase, Daisuke Nakano, Nicolas Pelisch, Hirofumi Hitomi, Hiroyuki Kobori, Satoshi Morimoto, Hirohito Mori, Tsutomu Masaki, Koji Ohmori, Masakazu Kohno, Atsuhiro Ichihara, Akira Nishiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 122, Iss 2, Pp 103-108 (2013)
Angiotensin II (Ang II) infusion into rats elevates local angiotensin II levels through an AT1 receptor–dependent pathway in the kidney. We examined whether treatment with an angiotensin-converting enzyme (ACE) inhibitor, temocapril, or an AT1-rece
Externí odkaz:
https://doaj.org/article/dc7a2d1f22794a678ec7b5df0a2c4878
Autor:
Nicolas Pelisch, Takashi Dan, Atsuhiko Ichimura, Hiroki Sekiguchi, Douglas E Vaughan, Charles van Ypersele de Strihou, Toshio Miyata
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124510 (2015)
Multiple sclerosis (MS) is characterized by inflammatory demyelination and deposition of fibrinogen in the central nervous system (CNS). Elevated levels of a critical inhibitor of the mammalian fibrinolitic system, plasminogen activator inhibitor 1 (
Externí odkaz:
https://doaj.org/article/1a57e21a89df49eb9480bde40a663de0
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via the original article.
Publikováno v:
Neuroscience Letters. 660:51-56
Ryanodine receptors (RyRs) are highly conductive intracellular Ca2+ release channels and are widely expressed in many tissues, including the central nervous system. RyRs have been implicated in intracellular Ca2+ overload which can drive secondary da
Publikováno v:
Neurobiology of Disease, Vol 106, Iss, Pp 235-243 (2017)
Severed CNS axons often retract or dieback away from the injury site and fail to regenerate. The precise mechanisms underlying acute axonal dieback and secondary axonal degeneration remain poorly understood. Here we investigate the role of Ca2+ store
Autor:
Nicolas Pelisch, Ben C. Orem, Jacqueline M. Nally, Nicole S. Stivers, Joshua Williams, David P. Stirling
Publikováno v:
Experimental Neurology. 294:1-11
Microglia/macrophage activation and recruitment following spinal cord injury (SCI) is associated with both detrimental and reparative functions. Stimulation of the innate immune receptor Toll-like receptor-2 (TLR2) has shown to be beneficial followin