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pro vyhledávání: '"Nicolas Pease"'
Autor:
Wenxiu Ma, He Fang, Nicolas Pease, Galina N. Filippova, Christine M. Disteche, Joel B. Berletch
Publikováno v:
Biology of Sex Differences, Vol 13, Iss 1, Pp 1-17 (2022)
Highlights The majority of KDM6A targets are regulated from one allele or the other with allelic downregulation showing a maternal allele bias. Kdm6a knockout affects genes that have been implicated in phenotypes of Kabuki syndrome caused by KDM6A mu
Externí odkaz:
https://doaj.org/article/1c11c9b3996d4474b360b8c7cec490c4
Autor:
Galina N. Filippova, Christine M. Disteche, Joel B. Berletch, He Fang, Nicolas Pease, Wenxiu Ma
Publikováno v:
SSRN Electronic Journal.
SUMMARYKDM6A demethylates the repressive histone mark H3K27me3 and thus plays an important role in developmental gene regulation. KDM6A expression is female-biased due to escape from X inactivation, suggesting that this protein may play a role in sex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b48dec75a05d0cc85ccfa5f815820a9
https://doi.org/10.2139/ssrn.3345548
https://doi.org/10.2139/ssrn.3345548