A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain

Autor: Nicolas P Andrews, Justin X Boeckman, Colleen F Manning, Joe T Nguyen, Hannah Bechtold, Camelia Dumitras, Belvin Gong, Kimberly Nguyen, Deborah van der List, Karl D Murray, JoAnne Engebrecht, James S Trimmer

Publikováno v: eLife, Vol 8 (2019)

Generating recombinant monoclonal antibodies (R-mAbs) from mAb-producing hybridomas offers numerous advantages that increase the effectiveness, reproducibility, and transparent reporting of research. We report here the generation of a novel resource

Externí odkaz: https://doaj.org/article/59976df2d6b046219b7ee9969a2fedc2

Supplementary Figures 1-11, Tables 1-4 from ANCCA/ATAD2 Overexpression Identifies Breast Cancer Patients with Poor Prognosis, Acting to Drive Proliferation and Survival of Triple-Negative Cells through Control of B-Myb and EZH2

Autor: Hong-Wu Chen, Alexander D. Borowsky, Robert D. Cardiff, June X. Zou, Clifford G. Tepper, Nicolas P. Andrews, Abigael T. Gemo, Alexey S. Revenko, Ekaterina V. Kalashnikova

Supplementary Figures 1-11, Tables 1-4 from ANCCA/ATAD2 Overexpression Identifies Breast Cancer Patients with Poor Prognosis, Acting to Drive Proliferation and Survival of Triple-Negative Cells through Control of B-Myb and EZH2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::605ae0a0e56ff54554e78ee473d52cf3
https://doi.org/10.1158/0008-5472.22387526.v1

Targeting bromodomain protein ANCCA/ATAD2 enhances the efficacy of DNA‑damaging chemotherapy agents and radiation

Autor: Ming Fan, Jian Jian Li, Junjian Wang, Zhijian Duan, Jing Shen, Nicolas P. Andrews, Hongwu Chen, Christopher Z. Chen

Publikováno v: Oncology reports. 43(1)

Bromodomain proteins such as BRD4 chromatin regulator are attractive cancer therapeutic targets. ANCCA (AAA+ nuclear coregulatory cancer‑associated protein, also known as ATPase family AAA domain containing 2 or ATAD2) is a novel oncology drug targ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbeab72ffb9288ff5d44310e91f8b4ba
https://pubmed.ncbi.nlm.nih.gov/31789405

A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain

Autor: Kimberly Nguyen, Nicolas P. Andrews, Hannah Bechtold, Camelia Dumitras, Joe T Nguyen, Belvin Gong, Karl D Murray, Deborah van der List, Colleen F Manning, James S. Trimmer, Justin X Boeckman, JoAnne Engebrecht

Publikováno v: eLife, Vol 8 (2019)
Andrews, Nicolas P; Boeckman, Justin X; Manning, Colleen F; Nguyen, Joe T; Bechtold, Hannah; Dumitras, Camelia; et al.(2019). A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain.. eLife, 8. doi: 10.7554/elife.43322. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/4sx4q1pw
eLife

Generating recombinant monoclonal antibodies (R-mAbs) from mAb-producing hybridomas offers numerous advantages that increase the effectiveness, reproducibility, and transparent reporting of research. We report here the generation of a novel resource

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::905ee5fdfb1a6da16c5d026a76bf6a6a
https://escholarship.org/uc/item/4sx4q1pw

CD94/NKG2A Expression Is Associated with Proliferative Potential of CD8 T Cells during Persistent Polyoma Virus Infection

Autor: Nicolas P. Andrews, Anthony M. Byers, Aron E. Lukacher

Publikováno v: The Journal of Immunology. 176:6121-6129

Memory CD8 T cells comprise a critical component of durable immunity because of their capacity to rapidly proliferate and exert effector activity upon Ag rechallenge. During persistent viral infection, memory CD8 T cells repetitively encounter viral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c6b52e1f29b2546f1596754ee3a93d
https://doi.org/10.4049/jimmunol.176.10.6121