Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nicolas P Holcomb"'
Autor:
Justinn Barr, Maria Elena Gentile, Sunyoung Lee, Maya E Kotas, Maria Fernanda de Mello Costa, Nicolas P Holcomb, Abigail Jaquish, Gargi Palashikar, Marcella Soewignjo, Margaret McDaniel, Ichiro Matsumoto, Robert Margolskee, Jakob Von Moltke, Noam A Cohen, Xin Sun, Andrew E Vaughan
Publikováno v:
eLife, Vol 11 (2022)
While the lung bears significant regenerative capacity, severe viral pneumonia can chronically impair lung function by triggering dysplastic remodeling. The connection between these enduring changes and chronic disease remains poorly understood. We r
Externí odkaz:
https://doaj.org/article/08d5c8bc81ec449093dbff776b23790d
Autor:
Gan Zhao, Maria E. Gentile, Lulu Xue, Christopher V. Cosgriff, Aaron I. Weiner, Stephanie Adams-Tzivelekidis, Joanna Wong, Xinyuan Li, Sara Kass-Gergi, Nicolas P. Holcomb, Maria C. Basal, Kathleen M. Stewart, Joseph D. Planer, Edward Cantu, Jason D. Christie, Maria M. Crespo, Michael J. Mitchell, Nuala J. Meyer, Andrew E. Vaughan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Inflammation induced by lung infection is a double-edged sword, moderating both anti-viral and immune pathogenesis effects; the mechanism of the latter is not fully understood. Previous studies suggest the vasculature is involved in tissue i
Externí odkaz:
https://doaj.org/article/298e4f96eba74047b28b7e392be57e41
Autor:
Gan Zhao, Maria E. Gentile, Lulu Xue, Christopher V. Cosgriff, Aaron I. Weiner, Stephanie Adams-Tzivelekidis, Joanna Wong, Xinyuan Li, Sara Kass-Gergi, Nicolas P. Holcomb, Maria C. Basal, Kathleen M. Stewart, Joseph D. Planer, Edward Cantu, Jason D. Christie, Maria M. Crespo, Michael J. Mitchell, Nuala J. Meyer, Andrew E. Vaughan
Publikováno v:
bioRxiv
Inflammation upon infectious lung injury is a double-edged sword: while tissue-infiltrating immune cells and cytokines are necessary to control infection, these same factors often aggravate injury. Full appreciation of both the sources and targets of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f06f4517047ef22e053a3f66a0fc31b
https://europepmc.org/articles/PMC10245987/
https://europepmc.org/articles/PMC10245987/
Autor:
Maria Elena Gentile, Justinn Barr, Sunyoung Lee, Maya E Kotas, Maria Fernanda de Mello Costa, Nicolas P Holcomb, Abigail Jaquish, Gargi Palashikar, Marcella Soewignjo, Margaret McDaniel, Ichiro Matsumoto, Robert Margolskee, Jakob Von Moltke, Noam A Cohen, Xin Sun, Andrew E Vaughan
While the lung bears significant regenerative capacity, severe viral pneumonia can chronically impair lung function by triggering dysplastic remodeling. The connection between these enduring changes and chronic disease remains poorly understood. We r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad131a81596f599d1bc19a9071f4fff3
https://escholarship.org/uc/item/63s758hd
https://escholarship.org/uc/item/63s758hd
Autor:
Aaron I. Weiner, Gan Zhao, Hanna M. Zayas, Nicolas P. Holcomb, Stephanie Adams-Tzivelekidis, Joanna Wong, Maria E. Gentile, Dyuthi Reddy, Joey Wei, Gargi Palashikar, Kwaku K. Quansah, Andrew E. Vaughan
Publikováno v:
Cell reports. 41(11)
The lung exhibits a robust, multifaceted regenerative response to severe injuries such as influenza infection, during which quiescent lung-resident epithelial progenitors participate in two distinct reparative pathways: functionally beneficial regene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca787f31bbbf6e15bd6f0b069bbd9d0
https://pubmed.ncbi.nlm.nih.gov/36516758
https://pubmed.ncbi.nlm.nih.gov/36516758
Autor:
Ferhat Ay, Katerina Kraft, Marco Michalski, Peter Fraser, David M. Gilbert, Claudia Trevilla-Garcia, Juan Carlos Rivera-Mulia, Abhijit Chakraborty, Mats Ljungman, Brian K. Washburn, Nicolas P. Holcomb, Benoit G. Bruneau, Michelle T. Paulsen, Jesse L. Turner, Jiao Sima, Daniel A. Bartlett, Peiyao A. Zhao, Stefan Mundlos, Elphège P. Nora, Vishnu Dileep, Kyle N. Klein
Publikováno v:
Cell, vol 176, iss 4
The temporal order of DNA replication (replication timing [RT]) is highly coupled with genome architecture, but cis-elements regulating either remain elusive. We created a series of CRISPR-mediated deletions and inversions of a pluripotency-associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26187b7d2231ceeca461f1bdadfca0a9
https://pubmed.ncbi.nlm.nih.gov/30735630
https://pubmed.ncbi.nlm.nih.gov/30735630