Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nicolas O Riffo-Lepe"'
Autor:
Juan P. Toledo, Eduardo J. Fernández-Pérez, Ildete L. Ferreira, Daniela Marinho, Nicolas O. Riffo-Lepe, Benjamin N. Pineda-Cuevas, Luis F. Pinochet-Pino, Carlos F. Burgos, A. Cristina Rego, Luis G. Aguayo
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Alzheimer’s disease (AD) is the most common cause of senile dementia worldwide, characterized by both cognitive and behavioral deficits. Amyloid beta peptide (Aβ) oligomers (AβO) have been found to be responsible for several pathological mechanis
Externí odkaz:
https://doaj.org/article/fac38986a80140b0947016cc157e3ad6
Autor:
Eduardo J Fernández-Pérez, L. Armijo-Weingart, Luis G. Aguayo, Scarlet Gallegos, Nicolas O Riffo-Lepe, A. Araya, F. Cayuman
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Several previous studies showed that hippocampus and cortex are affected in Alzheimer’s disease (AD). However, other brain regions have also been found to be affected and could contribute with new critical information to the pathophysiological basi
Autor:
Subramanian Boopathi, Denisse Bascuñán, Wendy González, Juliana González-Sanmiguel, Eduardo J Fernández-Pérez, Nicolas O Riffo-Lepe, Benjamín Vicente, A. Fernández-Pérez, Maximiliano Figueroa, Luis G. Aguayo, Catalina Bobadilla-Azócar, Carlos F. Burgos
Publikováno v:
ACS Chemical Neuroscience. 11:3064-3076
Oligomeric β-amyloid peptide (Aβ) is one of the main neurotoxic agents of Alzheimer's disease (AD). Oligomers associate to neuronal membranes, forming "pore-like" structures that cause intracellular calcium and neurotransmitter dyshomeostasis, lead
Autor:
Christian Peters, Jérôme Epsztein, Luis G. Aguayo, Rakez Kayed, Denisse Bascuñán, Urmi Sengupta, Peter James Morgan, Nicolas O Riffo-Lepe, Caroline Filippi, Braulio Muñoz, María Paz Espinoza, Romain Bourboulou, Eduardo J Fernández-Pérez
Publikováno v:
Aging Cell
Aging Cell, Wiley Open Access, 2021, ⟨10.1111/acel.13455⟩
Aging Cell, Wiley Open Access, 2021, ⟨10.1111/acel.13455⟩
Intracellular amyloid beta oligomer (iAβo) accumulation and neuronal hyperexcitability are two crucial events at early stages of Alzheimer's disease (AD). However, to date, no mechanism linking iAβo with an increase in neuronal excitability has bee
Autor:
Eduardo J Fernández-Pérez, Christian Peters, Urmi Sengupta, María Paz Espinoza, Luis G. Aguayo, Jerome Epsztein, Nicolas O Riffo-Lepe, Romain Bourboulou, Braulio Muñoz, Caroline Filippi, Rakez Kayed, Denisse Bascuñán, Peter James Morgan
BackgroundIntracellular amyloid-beta oligomers (iAβo) accumulation and neuronal hyperexcitability are two crucial events at early stages of Alzheimer’s disease (AD). However, to date, no mechanism linking them has been reported.MethodsHere, the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c435f3eb894f4107ed288531f835b4e
https://hal-amu.archives-ouvertes.fr/hal-03009671
https://hal-amu.archives-ouvertes.fr/hal-03009671
Autor:
Benjamín Vicente, Nicolas O Riffo-Lepe, Juliana González-Sanmiguel, Eduardo J Fernández-Pérez, Christian Peters, Fernando J. Sepúlveda, Denisse Bascuñán, Luis G. Aguayo, Robert W. Peoples, Susana A. Sanchez
Publikováno v:
Frontiers in Aging Neuroscience
Frontiers In Aging Neuroscience
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Frontiers in Neuroscience
Frontiers in Aging Neuroscience, Vol 10 (2018)
Frontiers In Aging Neuroscience
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Frontiers in Neuroscience
Frontiers in Aging Neuroscience, Vol 10 (2018)
Background: The beta-amyloid peptide (Aβ) involved in Alzheimer’s disease (AD) has been described to associate/aggregate on the cell surface disrupting the membrane through pore formation and breakage. However, molecular determinants involved for