Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Nicolas Nicastro"'
Publikováno v:
NeuroImage: Clinical, Vol 42, Iss , Pp 103592- (2024)
A proportion of patients clinically diagnosed with Parkinson’s disease (PD) can have a 123I-FP-CIT-SPECT scan without evidence of dopaminergic deficit (SWEDD), generating a debate about the underlying biological mechanisms. This study investigated
Externí odkaz:
https://doaj.org/article/ed459926cb4847a082f9345781e5bcb5
Autor:
Amira Soliman, Jose R. Chang, Kobra Etminani, Stefan Byttner, Anette Davidsson, Begoña Martínez-Sanchis, Valle Camacho, Matteo Bauckneht, Roxana Stegeran, Marcus Ressner, Marc Agudelo-Cifuentes, Andrea Chincarini, Matthias Brendel, Axel Rominger, Rose Bruffaerts, Rik Vandenberghe, Milica G. Kramberger, Maja Trost, Nicolas Nicastro, Giovanni B. Frisoni, Afina W. Lemstra, Bart N. M. van Berckel, Andrea Pilotto, Alessandro Padovani, Silvia Morbelli, Dag Aarsland, Flavio Nobili, Valentina Garibotto, the Alzheimer’s Disease Neuroimaging Initiative, Miguel Ochoa-Figueroa
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 22, Iss S6, Pp 1-15 (2022)
Abstract Background In recent years, neuroimaging with deep learning (DL) algorithms have made remarkable advances in the diagnosis of neurodegenerative disorders. However, applying DL in different medical domains is usually challenged by lack of lab
Externí odkaz:
https://doaj.org/article/1e31be5db89c45979ee82efd965f3f6d
Publikováno v:
Brain Sciences, Vol 13, Iss 5, p 726 (2023)
(1) Background: panic attack is often regarded as a benign disorder with variable physical and psychological symptoms. (2) Case Presentation: We here report the case of a 22-year-old patient known for an episode of motor functional neurological disor
Externí odkaz:
https://doaj.org/article/d6e36c57d9d84044b643d711b14b17b3
Autor:
Nicolas Nicastro, Negin Holland, George Savulich, Stephen F. Carter, Elijah Mak, Young T. Hong, Selena Milicevic Sephton, Tim D. Fryer, Franklin I. Aigbirhio, James B. Rowe, John T. O’Brien
Publikováno v:
European Journal of Hybrid Imaging, Vol 4, Iss 1, Pp 1-7 (2020)
Abstract Objective Dementia with Lewy bodies (DLB) is a common cause of dementia, but atrophy is mild compared to Alzheimer’s disease. We propose that DLB is associated instead with severe synaptic loss, and we test this hypothesis in vivo using po
Externí odkaz:
https://doaj.org/article/635372aa80de47148e5ac5852312c09b
Publikováno v:
BMC Neurology, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Neuropathological data and nuclear medicine imaging show extensive serotonergic impairment in Parkinson’s disease (PD). We undertook a case-controlled analysis of 123I-FP-CIT SPECT images to measure extrastriatal serotonergic tr
Externí odkaz:
https://doaj.org/article/3dfa72b4ed424549b4fd77994aa72ce0
Autor:
Audrey Low, Elijah Mak, Maura Malpetti, Leonidas Chouliaras, Nicolas Nicastro, Li Su, Negin Holland, Timothy Rittman, Patricia Vázquez Rodríguez, Luca Passamonti, W Richard Bevan‐Jones, PP Simon Jones, James B. Rowe, John T. O'Brien
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 690-699 (2019)
Abstract Introduction Although widespread cortical asymmetries have been identified in Alzheimer's disease (AD), thalamic asymmetries and their relevance to clinical severity in AD remain unclear. Methods Lateralization indices were computed for indi
Externí odkaz:
https://doaj.org/article/2453552f94744ec78af5f01efc8e2b40
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 10, Pp 2133-2136 (2019)
Abstract There is evidence of increased microglial activation in Parkinson’s disease (PD) as shown by in vivo PET ligand such as 11C‐PK11195. In addition, diffusion tensor imaging (DTI) imaging reveals widespread changes in PD, especially when th
Externí odkaz:
https://doaj.org/article/170f01c7993f45d1ae7f7e5060aca091
Publikováno v:
NeuroImage: Clinical, Vol 32, Iss , Pp 102791- (2021)
Introduction: presence hallucinations (PH) are frequent in dementia with Lewy bodies (DLB), but their cortico-subcortical origin is unknown. Recent studies have defined key frontal and temporal areas contributing to the occurrence of PH (PH-network)
Externí odkaz:
https://doaj.org/article/29b9562b9b384ab7a448590aaf65cedc
Autor:
Audrey Low, Elijah Mak, James D. Stefaniak, Maura Malpetti, Nicolas Nicastro, George Savulich, Leonidas Chouliaras, Hugh S. Markus, James B. Rowe, John T. O’Brien
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
BackgroundThe peak width of skeletonized mean diffusivity (PSMD) has been proposed as a fully automated imaging marker of relevance to cerebral small vessel disease (SVD). We assessed PSMD in relation to conventional SVD markers, global measures of n
Externí odkaz:
https://doaj.org/article/c6db892f90a548be873e9c7ed014c661
Autor:
Nicolas Nicastro, Elijah Mak, Guy B. Williams, Ajenthan Surendranathan, W Richard Bevan-Jones, Luca Passamonti, Patricia Vàzquez Rodrìguez, Li Su, Robert Arnold, Tim D. Fryer, Young T. Hong, Franklin I. Aigbirhio, James B. Rowe, John T. O'Brien
Publikováno v:
NeuroImage: Clinical, Vol 25, Iss , Pp - (2020)
Dementia with Lewy bodies (DLB) is characterized by alpha-synuclein protein deposition with variable degree of concurrent Alzheimer's pathology. Neuroinflammation is also increasingly recognized as a significant contributor to degeneration. We aimed
Externí odkaz:
https://doaj.org/article/849c0de96fee4c9bb848a84cdc801a14