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Autor:
Muhsen Al-Dhalimy, Eugenio Montini, Patrice K. Held, Milton J. Finegold, Meenakshi Noll, Markus Grompe, Mark A. Kay, Stephen R. Yant, Nicolas Morcinek
Publikováno v:
Molecular Therapy. 6(6):759-769
Gene therapy applications of naked DNA constructs for genetic disorders have been limited because of lack of permanent transgene expression. This limitation, however, can be overcome by the Sleeping Beauty (SB) transposable element, which can achieve