Powder Self-Emulsifying Drug Delivery System for Mitotane: In Vitro and In Vivo Evaluation

Autor: Mohamed Skiba, Valentin Lefébure, Frederic Bounoure, Nicolas Milon, Michael Thomas, Herve Lefebvre, Lahiani-Skiba Malika

Publikováno v: Pharmaceutics, Vol 16, Iss 9, p 1194 (2024)

Drug Delivery Systems (DDSs) of known drugs are prominent candidates for new and more effective treatments of various diseases, as they may increase drug solubility, dissolution velocity, and bioavailability. Mitotane (o,p′-dichlorodimethyl dichlor

Externí odkaz: https://doaj.org/article/a034cde9cb2947478ad9bad2c1b047b0

Enhanced Dissolution and Oral Bioavailability of Cyclosporine A: Microspheres Based on αβ-Cyclodextrins Polymers

Autor: Malika Lahiani-Skiba, Francois Hallouard, Frederic Bounoure, Nicolas Milon, Youness Karrout, Mohamed Skiba

Publikováno v: Pharmaceutics, Vol 10, Iss 4, p 285 (2018)

Cyclosporine (CsA) has a selective property of suppressing various T-lymphocyte functions. This is of utmost importance in preventing allograft rejection by several organ transplantations, as well as in the treatment of systemic and local autoimmune

Externí odkaz: https://doaj.org/article/beac2645088949248c8f217729f604cd

A tunable filter for high molecular weight DNA selection and linked-read sequencing

Autor: Adrien Castinel, Frederic Ginot, Aurélien Bancaud, Audrey Gibert, Olivier Bouchez, Géraud Bouwmans, Juan-Luis Fuentes Rojas, Cécile Donnadieu, Audrey Boutonnet, Laurent Bigot, Nicolas Milon, Karen Baudelle

Publikováno v: Lab on a Chip
Lab on a Chip, Royal Society of Chemistry, 2020, 20 (1), pp.175-184. ⟨10.1039/C9LC00965E⟩
Lab on a Chip, Royal Society of Chemistry, 2020, ⟨10.1039/C9LC00965E⟩
Lab on a Chip, 2020, 20 (1), pp.175-184. ⟨10.1039/C9LC00965E⟩

International audience; In third generation sequencing, the production of quality data requires the selection of molecules longer than ∼20 kbp, but the size selection threshold of most purification technologies is smaller than this target. Here, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ffc272736ebef73ca83c6e29fbca888
https://doi.org/10.1039/c9lc00965e

μLAS technology for DNA isolation coupled to Cas9-assisted targeting for sequencing and assembly of a 30 kb region in plant genome

Autor: Aurélien Bancaud, Carine Satge, Tslil Gabrieli, Sandra Moreau, Caroline Callot, Audrey Boutonnet, Arnaud Bellec, Hélène Bergès, Margaux-Alison Fustier, Nicolas Milon, Stéphane Cauet, Laure Saias, Céline Chantry-Darmon, Frederic Ginot

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, 2019, 47 (15), pp.8050-8060. ⟨10.1093/nar/gkz632⟩
Nucleic Acids Research, Oxford University Press, 2019, 47 (15), pp.8050-8060. ⟨10.1093/nar/gkz632⟩

Cas9-assisted targeting of DNA fragments in complex genomes is viewed as an essential strategy to obtain high-quality and continuous sequence data. However, the purity of target loci selected by pulsed-field gel electrophoresis (PFGE) has so far been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6163922e64c62c6942c0b2cf628ef2d
https://hal.laas.fr/hal-02338524

Inclusion and removal of pharmaceutical residues from aqueous solution using water-insoluble cyclodextrin polymers

Autor: L. Moulahcene, Nicolas Milon, M. Lahiani-Skiba, M. Benamor, O. Senhadji, Mohamed Skiba

Publikováno v: Chemical Engineering Research and Design. 97:145-158

A novel insoluble cyclodextrin polymers (PolyCyC®) (monopolymer, bipolymer, tripolymer and tetrapolymer) containing different cyclodextrins (α, β, γ-cyclodextrin) crosslinked with citric acid were used for removing progesterone as an endocrine di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a74e0ea17a4e59691e0a6898c2a8745f
https://doi.org/10.1016/j.cherd.2014.08.023