Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nicolas Margot"'
Autor:
Jan Weber, Justine D Rose, Ana C Vazquez, Dane Winner, Nicolas Margot, Damian J McColl, Michael D Miller, Miguel E Quiñones-Mateu
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65631 (2013)
Most studies describing phenotypic resistance to integrase strand transfer inhibitors have analyzed viruses carrying only patient-derived HIV-1 integrase genes (INT-recombinant viruses). However, to date, many of the patients on INSTI-based treatment
Externí odkaz:
https://doaj.org/article/cdf2f9aec6404be7b22c7ae4ed2c43b3
Publikováno v:
Journal of Medical Virology. 95
Autor:
Qi Liu, Chien-Hung Chou, Eda Canales, Roman Sakowicz, Steven Bondy, Tomas Cihlar, Albert Liclican, Diana M. Brainard, Anita Niedziela-Majka, William Rowe, Nikolai Novikov, Shekeba Ahmadyar, John R. Somoza, Randall L. Halcomb, Cheryl K. McDonald, Carina E. Cannizzaro, Nicolas Margot, Debi Jin, George Stepan, Qiaoyin Wu, Eric Hu, Judy Mwangi, Stephanie A. Leavitt, Todd C. Appleby, Robert L. Anderson, Scott E. Lazerwith, Schroeder Scott D, Tse Winston C, Gediminas Brizgys, Rebecca Begley, Yili Xu, Scott Sellers, Scott A. Wolckenhauer, Wesley I. Sundquist, Derek Hansen, Philip Morganelli, Andrew Mulato, Sheila Clancy, Xiaohong Liu, Anna Chiu, Eric S. Daar, Renee R. Ram, S. Swaminathan, Anne E. Chester, Melanie H. Wong, Ya-Pei Liu, John O. Link, Michael Graupe, Luong K. Tsai, Christian Callebaut, Latesh Lad, William E. Lee, Rujuta A. Bam, Terrence Z. Cai, Bing Lu, John K. Ling, Roland D. Saito, Magdeleine Hung, Armando G. Villaseñor, Peter Ruane, Nikos Pagratis, Martin S. Rhee, David Koditek, Gordon Crofoot, Giuseppe A. Papalia, Stephen R. Yant, Rob Hyland, Helen Yu, Jim Zheng, Jennifer R. Zhang, Gary I. Sinclair, Jiayao Li, Eric Singer
Publikováno v:
Nature
Oral antiretroviral agents provide life-saving treatments for millions of people living with HIV, and can prevent new infections via pre-exposure prophylaxis1–5. However, some people living with HIV who are heavily treatment-experienced have limite
Autor:
Nicolas Margot, Laurie Vanderveen, Vidula Naik, Renee Ram, PC Parvangada, Ross Martin, Martin Rhee, Christian Callebaut
Publikováno v:
The Journal of antimicrobial chemotherapy. 77(4)
Background Lenacapavir in vitro resistance selections identified seven mutations in HIV-1 capsid protein (CA) associated with reduced susceptibility. Objectives To analyse lenacapavir activity against lenacapavir-associated resistance mutations in mu
Autor:
Renee R, Ram, Paul, Duatschek, Nicolas, Margot, Michael, Abram, Romas, Geleziunas, Joseph, Hesselgesser, Christian, Callebaut
Publikováno v:
Antiviral therapy. 25(3)
Vesatolimod (VES; GS-9620) is a Toll-like receptor 7 (TLR7) agonist that directly activates human plasmacytoid dendritic cells (pDCs) and B lymphocytes resulting in direct and indirect production of cytokines and immune activation. VES is being evalu
Publikováno v:
Antimicrob Agents Chemother
Tenofovir alafenamide (TAF) and tenofovir disoproxil fumarate (TDF) are prodrugs of the HIV-1 nucleotide reverse transcriptase inhibitor tenofovir (TFV). In vivo, TAF achieves >4-fold-higher intracellular levels of TFV diphosphate (TFV-DP) compared t
Autor:
Gilles Manceau, Philippe Maingon, Jean-Christophe Vaillant, Mehdi Karoui, Jean-Baptiste Bachet, Jean-Marc Simon, Nicolas Margot, Jean-Philippe Spano, Jérémy Augustin, Armelle Bardier
Publikováno v:
Digestive and Liver Disease
Digestive and Liver Disease, WB Saunders, 2020, 52, pp.214-220. ⟨10.1016/j.dld.2019.07.013⟩
Digestive and Liver Disease, WB Saunders, 2020, 52, pp.214-220. ⟨10.1016/j.dld.2019.07.013⟩
Background Indication for adjuvant chemotherapy in ypN0 rectal cancer patients after chemoradiotherapy (CRT) is debated. The clinical significance of the presence of sterilized lymph nodes (LNS) in ypN0 patients remains to be determined. Aims To asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d981be09d278f1b9e70c473f29b3d615
https://hal.archives-ouvertes.fr/hal-03490001
https://hal.archives-ouvertes.fr/hal-03490001
Publikováno v:
The Journal of antimicrobial chemotherapy. 75(8)
The M184V/I reverse transcriptase mutation, which confers major resistance to lamivudine and emtricitabine, is still quite frequent in people living with HIV. The underlying presence of the M184V/I mutation may undermine virological outcomes of ART,
Autor:
Laurie VanderVeen, Nicolas Margot, Vidula Naik, Silvia Chang, Ross Martin, Hadas Dvory-Sobol, Martin Rhee, Christian Callebaut
Publikováno v:
Open Forum Infectious Diseases
Background Lenacapavir (LEN) is a first-in-class HIV-1 capsid (CA) inhibitor in clinical development for treatment and prevention of HIV-1 infection. CALIBRATE is an ongoing, phase 2 clinical study evaluating subcutaneous (SC) or oral LEN, in combina
Autor:
Ben Creavin, Yann Parc, Mathieu Faron, Olivier Benoit, Clotilde Debove, Jérémie H. Lefevre, Nicolas Margot, Emmanuel Tiret
Publikováno v:
Diseases of the colon and rectum. 62(1)
C-reactive protein is a useful negative predictive test for the development of anastomotic leakage following colorectal surgery. Evolution of procedures (laparoscopy, enhanced recovery program, early discharge, complex redo surgery) may influence C-r