Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nicolas M. Fédou"'
Publikováno v:
Organic Process Research & Development. 17:193-201
Tertiary carbinamine 5 is an isolated intermediate in the synthesis of a novel, inhaled β-2 adrenoreceptor agonist PF-610355. Process development for the key amide-formation and Ritter reactions, together with reaction understanding studies are disc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff6ef98f8ca6e404d83b12bb608d3ee1
https://doi.org/10.1021/op300341n
https://doi.org/10.1021/op300341n
Autor:
Stéphane Content, Thomas Dupont, Nicolas M. Fédou, Radoslav Penchev, Julian D. Smith, Flavien Susanne, Christopher Stoneley, Steven J. R. Twiddle
Publikováno v:
Organic Process Research & Development. 17:202-212
PF-610355 is a novel inhaled β-2 adrenoreceptor agonist. Process development of the final intermediate and the API are discussed with emphasis on the control of physical properties and subsequent i...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07da42fe99aa526dad4c9b561279821b
https://doi.org/10.1021/op300342y
https://doi.org/10.1021/op300342y