Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Nicolas Loyer"'
Autor:
Nicolas Loyer, Elizabeth KJ Hogg, Hayley G Shaw, Anna Pasztor, David H Murray, Greg M Findlay, Jens Januschke
Publikováno v:
eLife, Vol 13 (2024)
The generation of distinct cell fates during development depends on asymmetric cell division of progenitor cells. In the central and peripheral nervous system of Drosophila, progenitor cells respectively called neuroblasts or sensory organ precursors
Externí odkaz:
https://doaj.org/article/54589dcf729848159a41ff66a90b75e1
Autor:
Nicolas Loyer, Jens Januschke
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The highly proliferative neuroblasts of the Drosophila larval brain divide over many cell cycles in a polarized manner. Here the authors show that the orientation of the axis of NB divisions is defined by the position of their last-born daughter cell
Externí odkaz:
https://doaj.org/article/c8702ba68e1a4418b54ffbf2f36a8b86
Publikováno v:
eLife, Vol 7 (2018)
Cell fate assignment in the nervous system of vertebrates and invertebrates often hinges on the unequal distribution of molecules during progenitor cell division. We address asymmetric fate determinant localization in the developing Drosophila nervou
Externí odkaz:
https://doaj.org/article/3077cca4c70e454ca319eb93ab9afd61
Autor:
Inke Näthke, Kevin M. Haigis, Jens Januschke, Ian P. Newton, Nicolas Loyer, Alejandro Rojas-Fernandez, Melanie S. Volk, Michael H. Tatham, João A. Paulo, Olesja Popow
Control APC interactome network
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::495cf57e6f7dedda5c74d0d008d0c8a4
https://doi.org/10.1158/1541-7786.22514713
https://doi.org/10.1158/1541-7786.22514713
Autor:
Inke Näthke, Kevin M. Haigis, Jens Januschke, Ian P. Newton, Nicolas Loyer, Alejandro Rojas-Fernandez, Melanie S. Volk, Michael H. Tatham, João A. Paulo, Olesja Popow
Proteins measured by APC affinity enrichment-mass spectrometry and enrichment analysis of APC interactors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea5dedfdc702de65bb3633444671026
https://doi.org/10.1158/1541-7786.22514698
https://doi.org/10.1158/1541-7786.22514698
Autor:
Mariana Osswald, André Barros-Carvalho, Ana M Carmo, Nicolas Loyer, Patricia C Gracio, Claudio Sunkel, Catarina C Homem, Jens Januschke, Eurico Morais-de-Sá
Apical-basal polarity is an essential epithelial trait controlled by the evolutionarily conserved PAR-aPKC polarity network. Deregulation of polarity proteins disrupts tissue organization during development and in disease, but the underlying mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::301da47f1fd24f8515ecd398a2e07a11
https://doi.org/10.1101/2022.03.02.482459
https://doi.org/10.1101/2022.03.02.482459
Autor:
Jens, Januschke, Nicolas, Loyer
Publikováno v:
Journal of visualized experiments : JoVE. (166)
Drosophila is an important model system to study a vast range of biological questions. Various organs and tissues from different developmental stages of the fly such as imaginal discs, the larval brain or egg chambers of adult females or the adult in
Autor:
Jens Januschke, Nicolas Loyer
Publikováno v:
Journal of Visualized Experiments.
Drosophila is an important model system to study a vast range of biological questions. Various organs and tissues from different developmental stages of the fly such as imaginal discs, the larval brain or egg chambers of adult females or the adult in
Autor:
Jens Januschke, Nicolas Loyer
Publikováno v:
Current opinion in cell biology. 62
Asymmetric cell division (ACD) is the fundamental process through which one cell divides into two cells with different fates. In animals, it is crucial for the generation of cell-type diversity and for stem cells, which use ACD both to self-renew and
Autor:
Kevin M. Haigis, Joao A. Paulo, Olesja Popow, Michael H. Tatham, Ian P. Newton, Jens Januschke, Nicolas Loyer, Alejandro Rojas-Fernandez, Inke S. Näthke
Publikováno v:
SSRN Electronic Journal.
Adenomatous polyposis coli (APC) is the most frequently mutated gene in colorectal cancer. APC negatively regulates the pro-proliferative Wnt signaling pathway by promoting the degradation of β-catenin, but the extent to which APC exerts Wnt/^