Patient‐ and xenograft‐derived organoids recapitulate pediatric brain tumor features and patient treatments

Autor: Chiara Lago, Aniello Federico, Gloria Leva, Norman L Mack, Benjamin Schwalm, Claudio Ballabio, Matteo Gianesello, Luana Abballe, Isabella Giovannoni, Sofia Reddel, Sabrina Rossi, Nicolas Leone, Andrea Carai, Angela Mastronuzzi, Alessandra Bisio, Alessia Soldano, Concetta Quintarelli, Franco Locatelli, Marcel Kool, Evelina Miele, Luca Tiberi

Publikováno v: EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-28 (2023)

Abstract Brain tumors are the leading cause of cancer‐related death in children. Experimental in vitro models that faithfully capture the hallmarks and tumor heterogeneity of pediatric brain cancers are limited and hard to establish. We present a p

Externí odkaz: https://doaj.org/article/27709dc824264046a65fac5ef01127a4

Topographic Diversity of the Respiratory Tract Mycobiome and Alteration in HIV and Lung Disease

Autor: John Dermand, Laurence Huang, Eric C. Kleerup, Lorrie Lucht, Laura Tipton, Cathy Kessinger, Danielle Camp, Ruth M. Greenblatt, Adam Fitch, Matthew B. Rogers, Elodie Ghedin, Serena Fong, Lijia Cui, Stephen Stone, Lawrence A. Kingsley, Alison Morris, Nicolas Leo

Publikováno v: Cui, L; Lucht, L; Tipton, L; Rogers, MB; Fitch, A; Kessinger, C; et al.(2015). Topographic diversity of the respiratory tract mycobiome and alteration in HIV and lung disease. American Journal of Respiratory and Critical Care Medicine, 191(8), 932-942. doi: 10.1164/rccm.201409-1583OC. UCSF: Retrieved from: http://www.escholarship.org/uc/item/9bg8c3v0
American journal of respiratory and critical care medicine, vol 191, iss 8

RationaleMicrobiome studies typically focus on bacteria, but fungal species are common in many body sites and can have profound effects on the host. Wide gaps exist in the understanding of the fungal microbiome (mycobiome) and its relationship to lun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70baf07c2443924d9ed6f451cbb2f62
https://doi.org/10.1164/rccm.201409-1583oc

Long-term cardiology outcomes in children after early treatment for Chagas disease, an observational study.

Autor: Nicolás Leonel González, Guillermo Moscatelli, Samanta Moroni, Griselda Ballering, Laura Jurado, Nicolás Falk, Andrés Bochoeyer, Alejandro Goldsman, María Grippo, Héctor Freilij, Facundo Garcia Bournissen, Eric Chatelain, Jaime Altcheh

Publikováno v: PLoS Neglected Tropical Diseases, Vol 16, Iss 12, p e0010968 (2022)

BackgroundParasite persistence after acute infection with Trypanosoma cruzi is an important factor in the development of Chagas disease (CD) cardiomyopathy. Few studies have investigated the clinical effectiveness of CD treatment through the evaluati

Externí odkaz: https://doaj.org/article/a55c1893c5f9412f8d54693685e06af6

Síndrome mielodisplásico, osteoporosis y osteonecrosis maxilar asociada a medicamentos antirresortivos: reporte de un caso

Autor: Nicolás Leonardi, Federico Garola, Gerardo Gilligan, Eduardo Piemonte, Fiamma Cappella, René Panico

Publikováno v: Revista de la Facultad de Ciencias Médicas de Córdoba, Vol 77, Iss 4, Pp 373-377 (2020)

Introducción: La osteonecrosis maxilar asociada a medicamentos es una complicación encontrada en pacientes bajo tratamiento con drogas antirresortivas. Patologías oncológicas como mieloma múltiple, cáncer de mama y próstata y alteraciones óse

Externí odkaz: https://doaj.org/article/64b57263a11145b2813b37ca765f1362

Identifying the usefulness of microbial enumeration, diversity, and respiration for implementing strategies for intrinsic remediation

Autor: Nicolas, Leo

Hydrocarbon-utilizing bacteria have been found widely distributed in natural environments, their proportions affected by many factors, such as level of previous hydrocarbon exposure and from variations in soil conditions. This research compares micro

Externí odkaz: http://hdl.handle.net/1993/2749