Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Nicolas Legrand"'
Autor:
Mathilde Galhaut, Urban Lundberg, Romain Marlin, Robert Schlegl, Stefan Seidel, Ursula Bartuschka, Jürgen Heindl-Wruss, Francis Relouzat, Sébastien Langlois, Nathalie Dereuddre-Bosquet, Julie Morin, Maxence Galpin-Lebreau, Anne-Sophie Gallouët, Wesley Gros, Thibaut Naninck, Quentin Pascal, Catherine Chapon, Karine Mouchain, Guillaume Fichet, Julien Lemaitre, Mariangela Cavarelli, Vanessa Contreras, Nicolas Legrand, Andreas Meinke, Roger Le Grand
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-11 (2024)
Abstract Background The fight against COVID-19 requires mass vaccination strategies, and vaccines inducing durable cross-protective responses are still needed. Inactivated vaccines have proven lasting efficacy against many pathogens and good safety r
Externí odkaz:
https://doaj.org/article/b20cf0b0a10841d78b8331ab24c32b42
Publikováno v:
Infectious Diseases of Poverty, Vol 13, Iss 1, Pp 1-15 (2024)
Abstract Background Current soil-transmitted helminth (STH) control guidelines endorse the use of albendazole or mebendazole for school-based targeted preventive chemotherapy (PC), yet their reduced efficacy against Strongyloides stercoralis and Tric
Externí odkaz:
https://doaj.org/article/d86b4cd7005b47c3846c71d8c1d28b22
Autor:
Guillaume Cousin, Philip Meilland, Fabienne Damoiselet, Nicolas Legrand, Nils Naumann, Adam Ayeb
Publikováno v:
Research and Review Journal of Nondestructive Testing, Vol 1, Iss 1 (2023)
Laser ultrasonics (LUS) has shown through numerous studies and in-situ laboratory experiments, its suitability to track microstructural features evolution as well as metallurgical transformation in steels during thermal cycles with temperatures rea
Externí odkaz:
https://doaj.org/article/565abc65f7e74f438411224642f53d7a
Autor:
Nicolas Legrand, Olivier Etard, Fausto Viader, Patrice Clochon, Franck Doidy, Francis Eustache, Pierre Gagnepain
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105516- (2022)
Summary: Intrusive memories hijack consciousness and their control may lead to forgetting. However, the contribution of reflexive attention to qualifying a memory signal as interfering is unknown. We used machine learning to decode the brain’s elec
Externí odkaz:
https://doaj.org/article/227fdd73db93475393932fd5a5e3268f
Autor:
Shen Wang, Long Xu, Ting Mu, Mian Qin, Ping Zhao, Liang Xie, Linsen Du, Yue Wu, Nicolas Legrand, Karine Mouchain, Guillaume Fichet, Yi Liu, Wenhao Yin, Jin Zhao, Min Ji, Bo Gong, Michel Klein, Ke Wu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
We evaluated the immunogenicity and protective ability of a chimpanzee replication-deficient adenovirus vectored COVID-19 vaccine (BV-AdCoV-1) expressing a stabilized pre-fusion SARS-CoV-2 spike glycoprotein in golden Syrian hamsters. Intranasal admi
Externí odkaz:
https://doaj.org/article/79ff61ecfc7247569339f6c49270e4b1
Autor:
Aleksandr Ianevski, Rouan Yao, Eva Zusinaite, Laura Sandra Lello, Sainan Wang, Eunji Jo, Jaewon Yang, Erlend Ravlo, Wei Wang, Hilde Lysvand, Kirsti Løseth, Valentyn Oksenych, Tanel Tenson, Marc P. Windisch, Minna M. Poranen, Anni I. Nieminen, Svein Arne Nordbø, Mona Høysæter Fenstad, Gunnveig Grødeland, Pål Aukrust, Marius Trøseid, Anu Kantele, Eglė Lastauskienė, Astra Vitkauskienė, Nicolas Legrand, Andres Merits, Magnar Bjørås, Denis E. Kainov
Publikováno v:
Viruses, Vol 13, Iss 12, p 2489 (2021)
Background: There is an urgent need for new antivirals with powerful therapeutic potential and tolerable side effects. Methods: Here, we tested the antiviral properties of interferons (IFNs), alone and with other drugs in vitro. Results: While IFNs a
Externí odkaz:
https://doaj.org/article/fdd3427c779b42a5b595834a986d6d6d
Autor:
Aleksandr Ianevski, Rouan Yao, Hilde Lysvand, Gunnveig Grødeland, Nicolas Legrand, Valentyn Oksenych, Eva Zusinaite, Tanel Tenson, Magnar Bjørås, Denis E. Kainov
Publikováno v:
Viruses, Vol 13, Iss 9, p 1768 (2021)
SARS-CoV-2 and its vaccine/immune-escaping variants continue to pose a serious threat to public health due to a paucity of effective, rapidly deployable, and widely available treatments. Here, we address these challenges by combining Pegasys (IFNα)
Externí odkaz:
https://doaj.org/article/228754c4800149fb83c6624dc0ae3929
Autor:
Helene Strick-Marchand, Mathilde Dusséaux, Sylvie Darche, Nicholas D Huntington, Nicolas Legrand, Guillemette Masse-Ranson, Erwan Corcuff, James Ahodantin, Kees Weijer, Hergen Spits, Dina Kremsdorf, James P Di Santo
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119820 (2015)
Hepatic infections by hepatitis B virus (HBV), hepatitis C virus (HCV) and Plasmodium parasites leading to acute or chronic diseases constitute a global health challenge. The species tropism of these hepatotropic pathogens is restricted to chimpanzee
Externí odkaz:
https://doaj.org/article/43f6a4441a0b474391a41a2586d8f6e5
Autor:
Ebtisam El Filali, Suzanne Duijst, Johan K Hiralall, Nicolas Legrand, Thomas van Gulik, Ruurdtje Hoekstra, Jurgen Seppen
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
Possible risks and lack of donor livers limit application of liver transplantation. Liver cell transplantation is, at this moment, not a feasible alternative because engraftment in the liver is poor. Furthermore, there is also shortage of cells suita
Externí odkaz:
https://doaj.org/article/1dedab3c2dd3457ea53bb391aac89581
Autor:
Mireille Centlivre, Nicolas Legrand, Sofieke Klamer, Ying Poi Liu, Karin Jasmijn von Eije, Martino Bohne, Esther Siteur-van Rijnstra, Kees Weijer, Bianca Blom, Carlijn Voermans, Hergen Spits, Ben Berkhout
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Highly active antiretroviral therapy (HAART) has significantly improved the quality of life and the life expectancy of HIV-infected individuals. Still, drug-induced side effects and emergence of drug-resistant viral variants remain important issues t
Externí odkaz:
https://doaj.org/article/76143201c9954c7cb29e94052056bca8