Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Nicolas J. Pillon"'
Autor:
Nicolas J. Pillon, Brendan M. Gabriel, Lucile Dollet, Jonathon A. B. Smith, Laura Sardón Puig, Javier Botella, David J. Bishop, Anna Krook, Juleen R. Zierath
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The pathways that underlie the effects of exercise on metabolism remain incompletely described. Here, the authors perform a meta-analysis of transcriptomic data from 66 published datasets of human skeletal muscle. They identify pathways selectively a
Externí odkaz:
https://doaj.org/article/2c2929f8e4044f13af400f8dae2f008f
Autor:
Kristine Williams, Germán D. Carrasquilla, Lars Roed Ingerslev, Mette Yde Hochreuter, Svenja Hansson, Nicolas J. Pillon, Ida Donkin, Soetkin Versteyhe, Juleen R. Zierath, Tuomas O. Kilpeläinen, Romain Barrès
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101290- (2021)
Objectives: Regular physical exercise improves health by reducing the risk of a plethora of chronic disorders. We hypothesized that endurance exercise training remodels the activity of gene enhancers in skeletal muscle and that this remodeling contri
Externí odkaz:
https://doaj.org/article/a43dd0005ef848409fc736494902259e
Autor:
Gabryela Kuhnen, Tiago Guedes Russomanno, Marta Murgia, Nicolas J. Pillon, Martin Schönfelder, Henning Wackerhage
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12933 (2022)
Adult skeletal muscle fibres are classified as type 1, 2A, 2X, and 2B. These classifications are based on the expression of the dominant myosin heavy chain isoform. Muscle fibre-specific gene expression and proportions of muscle fibre types change du
Externí odkaz:
https://doaj.org/article/1dbf40b9308f4d34aecae09e5126aae0
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/50e2c27cc8b248fa843cede5b42f3646
Autor:
Mohd-Firdaus Maasar, Daniel C. Turner, Piotr P. Gorski, Robert A. Seaborne, Juliette A. Strauss, Sam O. Shepherd, Matt Cocks, Nicolas J. Pillon, Juleen R. Zierath, Andrew T. Hulton, Barry Drust, Adam P. Sharples
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The methylome and transcriptome signatures following exercise that are physiologically and metabolically relevant to sporting contexts such as team sports or health prescription scenarios (e.g., high intensity interval training/HIIT) has not been inv
Externí odkaz:
https://doaj.org/article/1c621adcd071416ca328bcb170186f4e
Autor:
Nicolas J. Pillon, Scott Frendo-Cumbo, Maya R. Jacobson, Zhi Liu, Paul L. Milligan, Hai Hoang Bui, Juleen R. Zierath, Philip J. Bilan, Joseph T. Brozinick, Amira Klip
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 7, Pp 1148-1163 (2018)
Ceramides contribute to obesity-linked insulin resistance and inflammation in vivo, but whether this is a cell-autonomous phenomenon is debated, particularly in muscle, which dictates whole-body glucose uptake. We comprehensively analyzed lipid speci
Externí odkaz:
https://doaj.org/article/7ce1e2b5a0df4eedb6bd2c3a76980825
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Circadian rhythms provide a selective advantage by anticipating organismal nutrient needs and guaranteeing optimal metabolic capacity during active hours. Impairment of circadian rhythms is associated with increased risk of type 2 diabetes and emergi
Externí odkaz:
https://doaj.org/article/875ab8d9d2da46a085ed364398778ee4
Autor:
Ahmed M. Abdelmoez, Oksana Dmytriyeva, Yasemin-Xiomara Zurke, Mette Trauelsen, Alesandra A. Marica, Mladen Savikj, Jonathon A. B. Smith, Claudia Monaco, Thue W. Schwartz, Anna Krook, Nicolas J. Pillon
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 324:E289-E298
Macrophages but not skeletal muscle cells respond to extracellular succinate via SUCNR1/GPR91.
Autor:
C. Brent Wakefield, Vanessa R. Lee, Danielle Johnston, Parastoo Boroumand, Nicolas J. Pillon, Samar Sayedyahossein, Brooke L. O’Donnell, Justin Tang, Rafael E. Sanchez-Pupo, Kevin J. Barr, Robert Gros, Lauren Flynn, Nica M. Borradaile, Amira Klip, Frank Beier, Silvia Penuela
Publikováno v:
Paediatrics Publications
Background: Pannexin 3 (PANX3) is a channel-forming glycoprotein that enables nutrient-induced inflammation in vitro, and genetic linkage data suggest that it regulates body mass index. Here, we characterized inflammatory and metabolic parameters in
Autor:
Nicolas J, Pillon
Publikováno v:
European journal of applied physiology.