Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Nicolas J Cabaton"'
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Akademický článek
Dynamic Metabolic Disruption in Rats Perinatally Exposed to Low Doses of Bisphenol-A.
Autor: Marie Tremblay-Franco, Nicolas J Cabaton, Cécile Canlet, Roselyne Gautier, Cheryl M Schaeberle, Fabien Jourdan, Carlos Sonnenschein, Florence Vinson, Ana M Soto, Daniel Zalko
Publikováno v: PLoS ONE, Vol 10, Iss 10, p e0141698 (2015)
Along with the well-established effects on fertility and fecundity, perinatal exposure to endocrine disrupting chemicals, and notably to xeno-estrogens, is strongly suspected of modulating general metabolism. The metabolism of a perinatally exposed i
Externí odkaz: https://doaj.org/article/ec144a6ab5944e06967473b89284f211
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2
Akademický článek
Low-dose BPA exposure alters the mesenchymal and epithelial transcriptomes of the mouse fetal mammary gland.
Autor: Perinaaz R Wadia, Nicolas J Cabaton, Michael D Borrero, Beverly S Rubin, Carlos Sonnenschein, Toshi Shioda, Ana M Soto
Publikováno v: PLoS ONE, Vol 8, Iss 5, p e63902 (2013)
Exposure of rodent fetuses to low doses of the endocrine disruptor bisphenol A (BPA) causes subtle morphological changes in the prenatal mammary gland and results in pre-cancerous and cancerous lesions during adulthood. To examine whether the BPA-ind
Externí odkaz: https://doaj.org/article/0d66171cd48b47e9af3132cda99c1eb1
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3
Biological Role of Pazopanib and Sunitinib Aldehyde Derivatives in Drug-Induced Liver Injury
Autor: Maud Maillard, Cécile Arellano, Christelle Vachoux, Christine Chevreau, Nicolas J. Cabaton, Frédéric Pont, Nathalie Saint-Laurent, Thierry Lafont, Etienne Chatelut, Fabienne Thomas
Publikováno v: Metabolites
Metabolites, 2022, 12 (9), pp.852. ⟨10.3390/metabo12090852⟩
Metabolites; Volume 12; Issue 9; Pages: 852
International audience; Tyrosine kinase inhibitors pazopanib and sunitinib are both used to treat advanced renal cell carcinoma but expose patients to an increased risk of hepatotoxicity. We have previously identified two aldehyde derivatives for paz
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e839410de5ca87f1cb3cded5d6ae32
https://pubmed.ncbi.nlm.nih.gov/36144257
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4
Gestational exposure to bisphenol A induces region-specific changes in brain metabolomic fingerprints in sheep
Autor: Davy Guignard, Cécile Canlet, Marie Tremblay-Franco, Elodie Chaillou, Roselyne Gautier, Véronique Gayrard, Nicole Picard-Hagen, Henri Schroeder, Fabien Jourdan, Daniel Zalko, Catherine Viguié, Nicolas J. Cabaton
Publikováno v: Environment International
Environment International, 2022, 165, pp.107336. ⟨10.1016/j.envint.2022.107336⟩
International audience; Fetal brain development depends on maternofetal thyroid function. In rodents and sheep, perinatal BPA exposure is associated with maternal and/or fetal thyroid disruption and alterations in central nervous system development a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21ac611edd00d64e4c4885cf16b60f0
https://hal.inrae.fr/hal-03701070/document
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6
Important Considerations for Sample Collection in Metabolomics Studies with a Special Focus on Applications to Liver Functions
Autor: Lorraine Smith, Cécile Canlet, Hervé Guillou, Nicolas J. Cabaton, Sandrine P. Claus, Joran Villaret-Cazadamont, Sandrine Ellero-Simatos
Publikováno v: Metabolites, Vol 10, Iss 3, p 104 (2020)
Metabolites
Metabolites, MDPI, 2020, 10 (3), pp.104. ⟨10.3390/metabo10030104⟩
International audience; Metabolomics has found numerous applications in the study of liver metabolism in health and disease. Metabolomics studies can be conducted in a variety of biological matrices ranging from easily accessible biofluids such as ur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec119031fed77bb3d43ea5f561d99626
https://www.mdpi.com/2218-1989/10/3/104
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7
Large-Scale Modeling Approach Reveals Functional Metabolic Shifts during Hepatic Differentiation
Autor: Anne Corlu, Sandrine Bruel, Nicolas J. Cabaton, Fabien Jourdan, Florence Vinson, Hélène Dubois-Pot-Schneider, Clément Frainay, Cécile Canlet, Daniel Zalko, Elodie Person, Fabrice Morel, Marie-Anne Robin, Florence Maurier, Nathalie Poupin, Bernard Fromenty
Publikováno v: Journal of Proteome Research
Journal of Proteome Research, American Chemical Society, 2019, 18 (1), pp.204-216. ⟨10.1021/acs.jproteome.8b00524⟩
Journal of Proteome Research, 2019, 18 (1), pp.204-216. ⟨10.1021/acs.jproteome.8b00524⟩
International audience; Being able to explore the metabolism of broad metabolizing cells is of critical importance in many research fields. This article presents an original modeling solution combining metabolic network and omics data to identify mod
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef1770ff94b676a0f76495f7be94eb31
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01937261
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8
An Untargeted Metabolomics Approach to Investigate the Metabolic Modulations of HepG2 Cells Exposed to Low Doses of Bisphenol A and 17β-Estradiol
Autor: Nicolas J. Cabaton, Nathalie Poupin, Cécile Canlet, Marie Tremblay-Franco, Marc Audebert, Jean-Pierre Cravedi, Anne Riu, Fabien Jourdan, Daniel Zalko
Publikováno v: Frontiers in Endocrinology
Frontiers in Endocrinology (9), . (2018)
Frontiers in Endocrinology, Vol 9 (2018)
The model xeno-estrogen bisphenol A (BPA) has been extensively studied over the past two decades, contributing to major advances in the field of endocrine disrupting chemicals research. Besides its well documented adverse effects on reproduction and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485e82b7a172b34515dd4fcc37476a89
https://doi.org/10.3389/fendo.2018.00571
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9
Bisphenol A exposure disrupts neurotransmitters through modulation of transaminase activity in the brain of rodents
Autor: Ana M. Soto, Nicolas J. Cabaton, Marie Tremblay-Franco, Daniel Zalko, Fabien Jourdan, Cécile Canlet
Publikováno v: Endocrinology 5 (157), 1736-1739. (2016)
Endocrinology
Endocrinology, Endocrine Society, 2016, 157 (5), pp.1736-1739. ⟨10.1210/en.2016-1207⟩
An increasing body of literature suggests that perinatal exposure to low doses of bisphenol A (BPA) has lasting effects on brain development and/or behavior in rodents (1, 2). Concerns about the occurrence of similar effects in humans are based on th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a0a2b422ad83509933edeb7201b1be
http://prodinra.inra.fr/record/356610
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10
Biotransformation of bisphenol F by human and rat liver subcellular fractions
Autor: Cécile Canlet, Estelle Rathahao, Elisabeth Perdu, Georges Delous, Nicolas J. Cabaton, Jean Pierre Cravedi, Daniel Zalko, Marie-Christine Chagnon
Publikováno v: Toxicology in Vitro
Toxicology in Vitro, Elsevier, 2008, 22 (7), pp.1697-1704. ⟨10.1016/j.tiv.2008.07.004⟩
Toxicology in Vitro, Elsevier, 2008, 22 (7), pp.1697-1704. 〈10.1016/j.tiv.2008.07.004〉
Bisphenol F [4,4'-dihydroxydiphenyl-methane] (BPF) has a broad range of applications in industry (liners lacquers, adhesives, plastics, coating of drinks and food cans). Free monomers of this bisphenol can be released into the environment and enter t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9142de9d3557da9c6e0fab6a9f05392
https://doi.org/10.1016/j.tiv.2008.07.004
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