Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nicolas Groulx"'
Autor:
Samira Mubareka, Nicolas Groulx, Eric Savory, Todd Cutts, Steven Theriault, James A. Scott, Chad J. Roy, Nathalie Turgeon, Elizabeth Bryce, George Astrakianakis, Shelley Kirychuk, Matthieu Girard, Gary Kobinger, Chao Zhang, Caroline Duchaine
Publikováno v:
Frontiers in Public Health, Vol 7 (2019)
The transmission of infectious microbes via bioaerosols is of significant concern for both human and animal health. However, gaps in our understanding of respiratory pathogen transmission and methodological heterogeneity persist. New developments hav
Externí odkaz:
https://doaj.org/article/fa73efac091843c6afe294f3b7168452
Publikováno v:
Influenza and Other Respiratory Viruses
Background Bioaerosol sampling devices are necessary for the characterization of infectious bioaerosols emitted by naturally-infected hosts with acute respiratory virus infections. Assessment of these devices under multiple experimental conditions wi
Publikováno v:
ISEE Conference Abstracts. 2018
Medical air is used in hospitals for patients suffering from a wide range of conditions. This air is typically produced by pressurizing outdoor air on-site and supplying it to patients through a le...
Autor:
Samira Mubareka, Lily Yip, Nicolas Groulx, Faisal Qureshi, Greg J. Evans, Hosna Movahhedinia, Kevin Katz, Paul Edwards
Publikováno v:
Atmospheric Environment. 219:117031
A significant proportion of hospitalized patients are dependent on medical air. Medical air is commonly produced on-site from filtered and compressed external air before delivery to patients through centralized piping. Little is known about how outsi
Publikováno v:
The Science of the total environment.
Anthropogenic air pollution is ubiquitous in urban areas worldwide. Microorganisms such as bacteria and fungi in addition to other biological matter like endotoxins and spores comingle with particulate matter (PM) air pollutants but have rarely been
Publikováno v:
Journal of Biological Chemistry. 286:42274-42282
Pore-forming toxins constitute a class of potent virulence factors that attack their host membrane in a two- or three-step mechanism. After binding to the membrane, often aided by specific receptors, they form pores in the membrane. Pore formation ei
Publikováno v:
The Journal of Physiology. 584:419-435
Extracellular ATP is a potent surfactant secretagogue but its origin in the alveolus, its mechanism(s) of release and its regulatory pathways remain unknown. Previously, we showed that hypotonic swelling of alveolar A549 cells induces Ca(2+)-dependen
Publikováno v:
The Journal of General Physiology
Pore-forming toxins, many of which are pathogenic to humans, are highly dynamic proteins that adopt a different conformation in aqueous solution than in the lipid environment of the host membrane. Consequently, their crystal structures obtained in aq
Publikováno v:
The Journal of membrane biology. 214(1)
To accommodate expanding volume (V) during hyposmotic swelling, animal cells change their shape and increase surface area (SA) by drawing extra membrane from surface and intracellular reserves. The relative contributions of these processes, sources a
Publikováno v:
Biophysical Journal. (3):535a
While crystal structures provide a structure with atomic resolution, it is only limitedly applicable to membrane toxins. The reason is that the mechanism of the toxins is based on a complete refolding of the protein ones it incorporates into the memb