Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Nicolas Gernigon"'
1
A multigram-scale lower E-factor procedure for MIBA-catalyzed direct amidation and its application to the coupling of alpha and beta aminoacids
Autor: Solmaz Fatemi, Dennis G. Hall, Nicolas Gernigon
Publikováno v: Green Chemistry. 17:4016-4028
The development of direct and atom-economical amidation methods is of high priority because of the importance of amides and peptides as components of pharmaceuticals and commodity chemicals. This article describes the identification of more economica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22ac04dced47f2cf609819d34e47a157
https://doi.org/10.1039/c5gc00659g
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2
Antiviral effect of ribonuclease conjugated oligodeoxynucleotides targeting the IRES RNA of the hepatitis C virus
Autor: Reynald Gillet, Valérie Abreu-Guerniou, Bertrand Carboni, Nicolas Gernigon, Maud Trotard, Carly Gamble, Fabienne Berrée, Brice Felden, Jacques Le Seyec
Publikováno v: Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2009, 19 (13), pp.3581-5. ⟨10.1016/j.bmcl.2009.04.139⟩
Bioorganic and Medicinal Chemistry Letters, 2009, 19 (13), pp.3581-5. ⟨10.1016/j.bmcl.2009.04.139⟩
International audience; Hepatitis C virus (HCV) translation initiation is mediated by a highly structured and conserved RNA, termed the Internal Ribosome Entry Site (IRES), located at the 5'-end of its single stranded RNA genome. It is a key target f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b54a9c242496ae4660eb28d27198ef11
https://doi.org/10.1016/j.bmcl.2009.04.139
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3
SN2′ Boron-Mediated Mitsunobu Reactions - A New One-Pot Three-Component Synthesis of Substituted Enamides and Enol Benzoates
Autor: Fabienne Berrée, Nicolas Gernigon, Chia Hui Lin, Alain Hercouet, Bertrand Carboni
Publikováno v: European Journal of Organic Chemistry. 2009:329-333
The conversion of (3-hydroxy-1-propen-1-yl)boronates to substituted enamides and enol benzoates is readily achieved in a one-pot procedure consisting of a regiocontrolled Mitsunobu reaction with convenient nucleophiles, followed by allylboration of a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a04b5fc9f0562c02c590cd378de40cd
https://doi.org/10.1002/ejoc.200800965
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5
ChemInform Abstract: Solid-Supported ortho-Iodoarylboronic Acid Catalyst for Direct Amidation of Carboxylic Acids
Autor: Dennis G. Hall, Hongchao Zheng, Nicolas Gernigon
Publikováno v: ChemInform. 44
Amides are a ubiquitous class of organic compounds endowed with great utility. There is a need for simple and effective catalytic methods for their direct formation from carboxylic acids and amines as a way to avoid the use of coupling reagents. We h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82522ab69b703fe49cf7266a23c55285
https://doi.org/10.1002/chin.201347033
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7
Direct amidation of carboxylic acids catalyzed by ortho-iodo arylboronic acids: catalyst optimization, scope, and preliminary mechanistic study supporting a peculiar halogen acceleration effect
Autor: Dennis G. Hall, Raed M. Al-Zoubi, Nicolas Gernigon
Publikováno v: The Journal of organic chemistry. 77(19)
The importance of amides as a component of biomolecules and synthetic products motivates the development of catalytic, direct amidation methods employing free carboxylic acids and amines that circumvent the need for stoichiometric activation or coupl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bccc3db9003a12f47b2094b924acc51f
https://pubmed.ncbi.nlm.nih.gov/23013456
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8
Synthesis and antibacterial activity of novel neamine derivatives: preponderant role of the substituent position on the neamine core
Autor: Nicolas Gernigon, Brice Felden, Valérie Bordeau, Fabienne Berrée, Bertrand Carboni
Publikováno v: Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry, 2012, 10 (24), pp.4720-30. ⟨10.1039/c2ob07065k⟩
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2012, 10 (24), pp.4720-30. ⟨10.1039/c2ob07065k⟩
International audience; A series of neamine derivatives were prepared from the cyclic carbonate and sulfate of 1,3,2',6'-tetraazido-3',4',-di-O-acetylneamine. Ring opening reactions with diversely substituted amines result in the formation of the cor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc5e434920483b84d3fb953c337e6f71
https://pubmed.ncbi.nlm.nih.gov/22585188
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9
ChemInform Abstract: SN2′ Boron-Mediated Mitsunobu Reactions - A New One-Pot Three-Component Synthesis of Substituted Enamides and Enol Benzoates
Autor: Fabienne Berrée, Chia Hui Lin, Nicolas Gernigon, Bertrand Carboni, Alain Hercouet
Publikováno v: ChemInform. 40
The conversion of (3-hydroxy-1-propen-1-yl)boronates to substituted enamides and enol benzoates is readily achieved in a one-pot procedure consisting of a regiocontrolled Mitsunobu reaction with convenient nucleophiles, followed by allylboration of a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6618cf8d0a06f5ff26915314d6994125
https://doi.org/10.1002/chin.200920063
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