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pro vyhledávání: '"Nicolas G.A. Grinberg"'
Autor:
Chetan K. Chana, Pierre Maisonneuve, Ganna Posternak, Nicolas G.A. Grinberg, Juline Poirson, Samara M. Ona, Derek F. Ceccarelli, Pavel Mader, Daniel J. St-Cyr, Victor Pau, Igor Kurinov, Xiaojing Tang, Dongjing Deng, Weiren Cui, Wenji Su, Letian Kuai, Richard Soll, Mike Tyers, Hannes L. Röst, Robert A. Batey, Mikko Taipale, Anne-Claude Gingras, Frank Sicheri
Publikováno v:
Journal of Medicinal Chemistry. 65:12725-12746
Targeted protein degradation (TPD) strategies exploit bivalent small molecules to bridge substrate proteins to an E3 ubiquitin ligase to induce substrate degradation. Few E3s have been explored as degradation effectors due to a dearth of E3-binding s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9bd44e2ad315c9a8487c6d1e86a88a
https://doi.org/10.1021/acs.jmedchem.2c00509
https://doi.org/10.1021/acs.jmedchem.2c00509
