Zobrazeno 1 - 10
of 623
pro vyhledávání: '"Nicolas G, Bazan"'
Autor:
Ying Wang, Xiang Zhang, Henrik Biverstål, Nicolas G. Bazan, Shuai Tan, Nailin Li, Makiko Ohshima, Marianne Schultzberg, Xiaofei Li
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 3, Pp 873-886 (2025)
Specialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer’s disease brain, suggesting that they constitute a novel target for the treatment of Alzheimer’s disease to prevent/
Externí odkaz:
https://doaj.org/article/3f4f59af8c0646529376dd19b3de51ed
Autor:
Sonia Do Carmo, Marie-Audrey I. Kautzmann, Surjyadipta Bhattacharjee, Bokkyoo Jun, Carolyn Steinberg, Joshua T. Emmerson, Janice C. Malcolm, Quentin Bonomo, Nicolas G. Bazan, A. Claudio Cuello
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Background Brain inflammation contributes significantly to the pathophysiology of Alzheimer’s disease, and it is manifested by glial cell activation, increased production of cytokines/chemokines, and a shift in lipid mediators from a pro-h
Externí odkaz:
https://doaj.org/article/fe06cee141254d99843b373e4c10aee1
Autor:
Hernan A. Bazan, Surjyadipta Bhattacharjee, Madigan M. Reid, Bokkyoo Jun, Connor Polk, Madeleine Strain, Linsey A. St Pierre, Neehar Desai, Patrick W. Daly, Jessica A. Cucinello-Ragland, Scott Edwards, Javier Recio, Julio Alvarez-Builla, James J. Cai, Nicolas G. Bazan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-35 (2024)
Abstract Safe and effective pain management is a critical healthcare and societal need. The potential for acute liver injury from paracetamol (ApAP) overdose; nephrotoxicity and gastrointestinal damage from chronic non-steroidal anti-inflammatory dru
Externí odkaz:
https://doaj.org/article/e955fc7d7b3b4d97b98770099763f826
Autor:
Nicolas G. Bazan, Andre Obenaus, Larissa Khoutorova, Pranab K. Mukherjee, Bokkyoo Jun, Rostyslav Semikov, Ludmila Belayev
Publikováno v:
Biomedicines, Vol 12, Iss 11, p 2555 (2024)
Background: In the United States, traumatic brain injury (TBI) contributes significantly to mortality and morbidity. Elovanoids (ELVs), a novel class of homeostatic lipid mediators we recently discovered and characterized, have demonstrated neuroprot
Externí odkaz:
https://doaj.org/article/01fc51d5ea8644eba3905677b8c18984
Autor:
Jorgelina M. Calandria, Surjyadipta Bhattacharjee, Sayantani Kala-Bhattacharjee, Pranab K. Mukherjee, Yuehan Feng, Jakob Vowinckel, Tobias Treiber, Nicolas G. Bazan
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-10 (2023)
Abstract The thioredoxin (TXN) system is an NADPH + H+/FAD redox-triggered effector that sustains homeostasis, bioenergetics, detoxifying drug networks, and cell survival in oxidative stress-related diseases. Elovanoid (ELV)-N34 is an endogenously fo
Externí odkaz:
https://doaj.org/article/dbebac66dc1540809737569171643c4e
Autor:
Madigan M. Reid, Ludmila Belayev, Larissa Khoutorova, Pranab K. Mukherjee, Andre Obenaus, Kierany Shelvin, Stacey Knowles, Sung-Ha Hong, Nicolas G. Bazan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Despite efforts to identify modulatory neuroprotective mechanisms of damaging ischemic stroke cascade signaling, a void remains on an effective potential therapeutic. The present study defines neuroprotection by very long-chain polyunsaturat
Externí odkaz:
https://doaj.org/article/fc704bbd2d7a486596a98cd9c5b843c9
Autor:
Yan Lu, Haibin Tian, Hongying Peng, Quansheng Wang, Bruce A. Bunnell, Nicolas G. Bazan, Song Hong
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Introduction: Stem cells can be used to treat diabetic mellitus and complications. ω3-docosahexaenoic acid (DHA) derived lipid mediators are inflammation-resolving and protective. This study found novel DHA-derived 7S,14R-dihydroxy-4Z,8E,10Z,12E,16Z
Externí odkaz:
https://doaj.org/article/a0e77f5eb1864955bb6454789918ba6f
Autor:
Whitney G Walkowski, Corinne L Richards-Zawacki, William C Gordon, Nicolas G Bazan, Hamilton E Farris
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0312578 (2024)
Research on visually driven behavior in anurans has often focused on Dendrobatoidea, a clade with extensive variation in skin reflectance, which is perceived to range from cryptic to conspicuous coloration. Because these skin patterns are important i
Externí odkaz:
https://doaj.org/article/eb962f50050241858f3d4fb90a56ed2e
Publikováno v:
Brain Sciences, Vol 14, Iss 3, p 211 (2024)
The development of noninvasive and cost-effective methods of detecting Alzheimer’s disease (AD) is essential for its early prevention and mitigation. We optimize the detection of AD using natural language processing (NLP) of spontaneous speech thro
Externí odkaz:
https://doaj.org/article/63fe752c0e634d4b9b16e2dbb87c69e1
Autor:
Dorota Wyczechowska, Paul G. Harch, Shelly Mullenix, Erin S. Fannin, Brenda B. Chiappinelli, Duane Jeansonne, Adam Lassak, Nicolas G. Bazan, Francesca Peruzzi
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Mild Traumatic Brain Injury (mild TBI)/concussion is a common sports injury, especially common in football players. Repeated concussions are thought to lead to long-term brain damage including chronic traumatic encephalopathy (CTE). With the worldwid
Externí odkaz:
https://doaj.org/article/9e3166f3de504649a5cd88fa423cb3f2