Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Nicolas Froger"'
Autor:
Thomas Boillot, Serge G Rosolen, Thomas Dulaurent, Frédéric Goulle, Philippe Thomas, Pierre-François Isard, Thierry Azoulay, Stéphanie Lafarge-Beurlet, Mike Woods, Sylvie Lavillegrand, Ivana Ivkovic, Nathalie Neveux, José-Alain Sahel, Serge Picaud, Nicolas Froger
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111873 (2014)
In both humans and dogs, the primary risk factor for glaucoma is high intraocular pressure (IOP), which may be caused by iridocorneal angle (ICA) abnormalities. Oxidative stress has also been implicated in retinal ganglion cell damage associated with
Externí odkaz:
https://doaj.org/article/1523eff2c22641df9d05fd5540423a59
Autor:
Nicolas Froger, Lucia Cadetti, Henri Lorach, Joao Martins, Alexis-Pierre Bemelmans, Elisabeth Dubus, Julie Degardin, Dorothée Pain, Valérie Forster, Laurent Chicaud, Ivana Ivkovic, Manuel Simonutti, Stéphane Fouquet, Firas Jammoul, Thierry Léveillard, Ryad Benosman, José-Alain Sahel, Serge Picaud
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e42017 (2012)
Retinal ganglion cell (RGC) degeneration occurs in numerous retinal diseases leading to blindness, either as a primary process like in glaucoma, or secondary to photoreceptor loss. However, no commercial drug is yet directly targeting RGCs for their
Externí odkaz:
https://doaj.org/article/e740b48505a24866897c89207d5cc94d
Autor:
Nicolas Froger
Publikováno v:
Biologie Aujourd’hui. 213:131-140
Discovered in the eighties by Pr Baulieu and colleagues, neurosteroids are a class of neuroactive brain-born steroids, which comprises the steroid hormones, their biosynthesis precursors and their metabolites. They can act through genomic as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97bdbcad87004a6b3eab42658023c51d
https://doi.org/10.1051/jbio/2019023
https://doi.org/10.1051/jbio/2019023
Autor:
Nicolas Froger, Serge Picaud, Ivana Ivkovic, Christophe Roubeix, Nadège Brunel, Frédéric Matonti, Valérie Forster, José-Alain Sahel, Christophe Baudouin
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, ⟨10.1038/s41598-020-68488-z⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Nature Publishing Group, 2020, ⟨10.1038/s41598-020-68488-z⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Vascular endothelial growth factor-A (VEGF) is the angiogenic factor promoting the pathological neovascularization in age-related macular degeneration (AMD) or diabetic macular edema (DME). Evidences have suggested a neurotrophic and neuroprotective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91fa7f29fec046e1e9bc8b8e67e180e5
https://doi.org/10.1038/s41598-020-68488-z
https://doi.org/10.1038/s41598-020-68488-z
Publikováno v:
Pharmacology & Therapeutics. 191:190-206
Neurosteroids are neuroactive brain-born steroids. They can act through non-genomic and/or through genomic pathways. Genomic pathways are largely described for steroid hormones: the binding to nuclear receptors leads to transcription regulation. Preg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4a3d467d3ea610fedb56df054ca0ed
https://doi.org/10.1016/j.pharmthera.2018.06.011
https://doi.org/10.1016/j.pharmthera.2018.06.011
Autor:
Nicolas, Froger
Publikováno v:
Biologie aujourd'hui. 213(3-4)
Discovered in the eighties by Pr Baulieu and colleagues, neurosteroids are a class of neuroactive brain-born steroids, which comprises the steroid hormones, their biosynthesis precursors and their metabolites. They can act through genomic as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97cda4765e68bc3015608de3aeb3d023
https://pubmed.ncbi.nlm.nih.gov/31829933
https://pubmed.ncbi.nlm.nih.gov/31829933
Autor:
Wahiba, Hadj-Saïd, Valérie, Fradot, Ivana, Ivkovic, José-Alain, Sahel, Serge, Picaud, Nicolas, Froger
Publikováno v:
Advances in experimental medicine and biology.
Retinal ganglion cell (RGC) degeneration occurs in numerous retinal diseases, either as a primary process like in glaucoma, or secondary to photoreceptor loss and no efficient compound targeting directly RGC neuroprotection is yet available. We previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e911cb71f8c5dae62471c547af7bab88
https://pubmed.ncbi.nlm.nih.gov/28849492
https://pubmed.ncbi.nlm.nih.gov/28849492
Autor:
Serge Picaud, Ivana Ivkovic, Valérie Fradot, José-Alain Sahel, Nicolas Froger, Wahiba Hadj-Saïd
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789402410778
Retinal ganglion cell (RGC) degeneration occurs in numerous retinal diseases, either as a primary process like in glaucoma, or secondary to photoreceptor loss and no efficient compound targeting directly RGC neuroprotection is yet available. We previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0633a0271e3d8582ac651e36f82628b1
https://doi.org/10.1007/978-94-024-1079-2_54
https://doi.org/10.1007/978-94-024-1079-2_54
Autor:
Nicolas Froger, Nathalie Neveux, David Gaucher, Serge Picaud, Lucia Cadetti, Larissa Moutsimilli, José-Alain Sahel, Yichao Fan, Luc Cynober, Serge G. Rosolen, Qing-Ping Wang, Firas Jammoul
Publikováno v:
Progress in Retinal and Eye Research. 41:44-63
Taurine is the most abundant amino acid in the retina. In the 1970s, it was thought to be involved in retinal diseases with photoreceptor degeneration, because cats on a taurine-free diet presented photoreceptor loss. However, with the exception of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a082421be1b367b4f876237c630ceaeb
https://doi.org/10.1016/j.preteyeres.2014.03.001
https://doi.org/10.1016/j.preteyeres.2014.03.001
Publikováno v:
Bulletin de l'Académie Vétérinaire de France. 167:253-260
Eye and taurine Taurine is the most abundant amino acid in retina. Although unclear, its role is mainly related to its powerful antioxidant properties. The taurine concentrations in tissues are regulated by an exogenous intake through the nutrition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1300e25ebd0b58537ca7e70c6deb1e6f
https://doi.org/10.4267/2042/54198
https://doi.org/10.4267/2042/54198