Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Nicolas Frances"'
Autor:
Javier Sanchez, Christina Claus, Christine McIntyre, Tamara Tanos, Axel Boehnke, Lena E. Friberg, Siv Jönsson, Nicolas Frances
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The majority of bispecific costimulatory antibodies in cancer immunotherapy are capable of exerting tumor-specific T-cell activation by simultaneously engaging both tumor-associated targets and costimulatory receptors expressed by T cells. The amount
Externí odkaz:
https://doaj.org/article/dfa2048939094ec19e21297c210bce9e
Autor:
Francis Williams Ojara, Andrea Henrich, Nicolas Frances, Yomna M. Nassar, Wilhelm Huisinga, Niklas Hartung, Kimberly Geiger, Stefan Holdenrieder, Markus Joerger, Charlotte Kloft
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 11, Pp 1714-1725 (2023)
Abstract Paclitaxel/platinum chemotherapy, the backbone of standard first‐line treatment of advanced non‐small cell lung cancer (NSCLC), exhibits high interpatient variability in treatment response and high toxicity burden. Baseline blood biomark
Externí odkaz:
https://doaj.org/article/a66563bd6bf14dcaa78e5deef69f42e4
Autor:
Javier Sánchez, Christina Claus, Rosmarie Albrecht, Brenda C. Gaillard, Joana Marinho, Christine McIntyre, Tamara Tanos, Axel Boehnke, Lena E. Friberg, Siv Jönsson, Nicolas Frances
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 11, Pp 1804-1818 (2023)
Abstract FAP‐4‐1BBL is a bispecific antibody exerting 4‐1BB‐associated T‐cell activation only while simultaneously bound to the fibroblast activation protein (FAP) receptor, expressed on the surface of cancer‐associated fibroblasts. The t
Externí odkaz:
https://doaj.org/article/eca39fbc381d48aebd104930c6c16670
Autor:
Truong, Hoai-Nam, Fournier, Carine, Hichami, Siham, Dole, Léna, Leroy, Fanny, Wendehenne, David, Nicolas-Francès, Valérie, Besson-Bard, Angélique
Publikováno v:
In Plant Stress June 2024 12
Autor:
Nicolas-Francès, Valérie, Besson-Bard, Angélique, Meschini, Stefano, Klinguer, Agnès, Bonnotte, Aline, Héloir, Marie-Claire, Citerne, Sylvie, Inès, Damien, Hichami, Siham, Wendehenne, David, Rosnoblet, Claire
Publikováno v:
In Plant Physiology and Biochemistry June 2024 211
Presents the goodness of fit plots when fitting a 1-compartmental model to the short term PK data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a1a7345b2f913d983a647248bc8c90
https://doi.org/10.1158/1535-7163.22508385.v1
https://doi.org/10.1158/1535-7163.22508385.v1
Autor:
Antje-Christine Walz, Marina Bacac, Thorsten Lehr, Florian Limani, Sarah Diggelmann, Jitka Somandin, Regula B. Buser, Sylvia Herter, Nicolas Frances, Miro J. Eigenmann, Tina Weinzierl, Arthur J. Van De Vyver
Experimental data triplicate values with model fit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236fc9f6a87241f542cdff136010e359
https://doi.org/10.1158/1535-7163.22521570.v1
https://doi.org/10.1158/1535-7163.22521570.v1
Autor:
Antje-Christine Walz, Marina Bacac, Thorsten Lehr, Florian Limani, Sarah Diggelmann, Jitka Somandin, Regula B. Buser, Sylvia Herter, Nicolas Frances, Miro J. Eigenmann, Tina Weinzierl, Arthur J. Van De Vyver
Targeted T-cell redirection is a promising field in cancer immunotherapy. T-cell bispecific antibodies (TCB) are novel antibody constructs capable of binding simultaneously to T cells and tumor cells, allowing cross-linking and the formation of immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660357c498b0b8984076522718e1e498
https://doi.org/10.1158/1535-7163.c.6543060
https://doi.org/10.1158/1535-7163.c.6543060
Autor:
Antje-Christine Walz, Marina Bacac, Thorsten Lehr, Florian Limani, Sarah Diggelmann, Jitka Somandin, Regula B. Buser, Sylvia Herter, Nicolas Frances, Miro J. Eigenmann, Tina Weinzierl, Arthur J. Van De Vyver
Estimated parameter values
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ceb060b2ec8eb42fe870e1ca310382
https://doi.org/10.1158/1535-7163.22521552.v1
https://doi.org/10.1158/1535-7163.22521552.v1
Autor:
Antje-Christine Walz, Marina Bacac, Thorsten Lehr, Florian Limani, Sarah Diggelmann, Jitka Somandin, Regula B. Buser, Sylvia Herter, Nicolas Frances, Miro J. Eigenmann, Tina Weinzierl, Arthur J. Van De Vyver
Supplementary section S1 describes the compound properties of cibisatamab as well as details on data generation, model development and modeling strategy applied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce5d10b23066566fc8b27cf6312e8fe
https://doi.org/10.1158/1535-7163.22521558
https://doi.org/10.1158/1535-7163.22521558