Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nicolas Fontrodona"'
Autor:
Lamya Ben Ameur, Paul Marie, Morgan Thenoz, Guillaume Giraud, Emmanuel Combe, Jean-Baptiste Claude, Sebastien Lemaire, Nicolas Fontrodona, Hélène Polveche, Marine Bastien, Antoine Gessain, Eric Wattel, Cyril F. Bourgeois, Didier Auboeuf, Franck Mortreux
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The nuclear factors κB (NF-κB) is a transcription factor involved in immune functions, inflammation, and cancer. Here, the authors show that the NF-κB factor RELA regulates splicing of target genes by recruiting DDX17 on chromatin upon expression
Externí odkaz:
https://doaj.org/article/b9b58d9a3e674e579917447295972cb5
Autor:
Sébastien Lemaire, Nicolas Fontrodona, Fabien Aubé, Jean-Baptiste Claude, Hélène Polvèche, Laurent Modolo, Cyril F. Bourgeois, Franck Mortreux, Didier Auboeuf
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-21 (2019)
Abstract Background Nucleotide composition bias plays an important role in the 1D and 3D organization of the human genome. Here, we investigate the potential interplay between nucleotide composition bias and the regulation of exon recognition during
Externí odkaz:
https://doaj.org/article/5a5d20b3977c4af3acdd667e1f6ebabc
Autor:
Sophie Terrone, Jessica Valat, Nicolas Fontrodona, Guillaume Giraud, Jean-Baptiste Claude, Emmanuel Combe, Audrey Lapendry, Hélène Polvèche, Lamya Ben Ameur, Arnaud Duvermy, Laurent Modolo, Pascal Bernard, Franck Mortreux, Didier Auboeuf, Cyril F Bourgeois
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2022, 50 (16), pp.9226-9246. ⟨10.1093/nar/gkac717⟩
Nucleic Acids Research, 2022, 50 (16), pp.9226-9246. ⟨10.1093/nar/gkac717⟩
DDX5 and DDX17 are DEAD-box RNA helicase paralogs which regulate several aspects of gene expression, especially transcription and splicing, through incompletely understood mechanisms. A transcriptome analysis of DDX5/DDX17-depleted human cells confir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1d6a01a835a5b2b2e253351d58ad00
https://hal.science/hal-03842696
https://hal.science/hal-03842696
Autor:
Guillaume Giraud, Didier Auboeuf, Jean-Baptiste Claude, Hélène Polvèche, Eric Wattel, Paul Marie, Nicolas Fontrodona, Lamya Ben Ameur, Marine Bastien, Antoine Gessain, Morgan Thenoz, Sébastien Lemaire, Cyril F. Bourgeois, Emmanuel Combe, Franck Mortreux
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.3045. ⟨10.1038/s41467-020-16853-x⟩
Nature Communications, 2020, 11 (1), pp.3045. ⟨10.1038/s41467-020-16853-x⟩
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.3045. ⟨10.1038/s41467-020-16853-x⟩
Nature Communications, 2020, 11 (1), pp.3045. ⟨10.1038/s41467-020-16853-x⟩
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Chronic NF-κB activation in inflammation and cancer has long been linked to persistent activation of NF-κB–responsive gene promoters. However, NF-κB factors also massively bind to gene bodies. Here, we demonstrate that recruitment of the NF-κB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57c9d1dd4a9fc2559b65caf732c2214
https://doi.org/10.1038/s41467-020-16853-x
https://doi.org/10.1038/s41467-020-16853-x
Autor:
Cyril F. Bourgeois, Laurent Modolo, Franck Mortreux, Hélène Polvèche, Nicolas Fontrodona, Fabien Aubé, Sébastien Lemaire, Didier Auboeuf, Jean-Baptiste Claude
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-21 (2019)
Genome Biology
Genome Biology
Background Nucleotide composition bias plays an important role in the 1D and 3D organization of the human genome. Here, we investigate the potential interplay between nucleotide composition bias and the regulation of exon recognition during splicing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af107cbd338e6d0a9fbf0c3d6e18cbd8
https://doi.org/10.1186/s13059-019-1869-y
https://doi.org/10.1186/s13059-019-1869-y
Autor:
Cyril F. Bourgeois, Fabien Aubé, Sébastien Lemaire, Franck Mortreux, Nicolas Fontrodona, Didier Auboeuf, Hélène Polvèche, Jean-Baptiste Claude, Laurent Modolo
To characterize the rules governing exon recognition during splicing, we analysed dozens of RNA-seq datasets and identified ~3,200 GC-rich exons and ~4,000 AT-rich exons whose inclusion depends on different sets of splicing factors. We show that GC-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faac5542644911802d617b220f39f533
https://doi.org/10.1101/605832
https://doi.org/10.1101/605832
Autor:
Lamya Ben Ameur, Morgan Thenoz, Guillaume Giraud, Emmanuel Combe, Jean-Baptiste Claude, Hélène Polveche, Nicolas Fontrodona, Marine Bastien, Antoine Gessain, Eric Wattel, Cyril F. Bourgeois, Didier Auboeuf, Franck Montreux
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79f9a6638cd487915bbf8186d2efca8c
https://doi.org/10.2139/ssrn.3312125
https://doi.org/10.2139/ssrn.3312125
Autor:
Cyril F. Bourgeois, Fabien Aubé, Léon-Charles Tranchevent, Sébastien Lemaire, Franck Mortreux, Hélène Polvèche, Laurent Modolo, Nicolas Fontrodona, Didier Auboeuf, Jean-Baptiste Claude
The inclusion of exons during the splicing process depends on the binding of splicing factors to short low-complexity regulatory sequences. The relationship between exonic splicing regulatory sequences and coding sequences is still poorly understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadba831f180372ac0391d953b8c18a6