Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Nicolas F. Fernandez"'
Autor:
Sara Costi, Laurel S. Morris, Abigail Collins, Nicolas F. Fernandez, Manishkumar Patel, Hui Xie, Seunghee Kim-Schulze, Emily R. Stern, Katherine A. Collins, Flurin Cathomas, Michael K. Parides, Alexis E. Whitton, Diego A. Pizzagalli, Scott J. Russo, James W. Murrough
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Increased levels of peripheral cytokines have been previously associated with depression in preclinical and clinical research. Although the precise nature of peripheral immune dysfunction in depression remains unclear, evidence from animal s
Externí odkaz:
https://doaj.org/article/ba742c5afe7d476aa19d67c3d88c7bb5
Autor:
Zichen Wang, Caroline D. Monteiro, Kathleen M. Jagodnik, Nicolas F. Fernandez, Gregory W. Gundersen, Andrew D. Rouillard, Sherry L. Jenkins, Axel S. Feldmann, Kevin S. Hu, Michael G. McDermott, Qiaonan Duan, Neil R. Clark, Matthew R. Jones, Yan Kou, Troy Goff, Holly Woodland, Fabio M R. Amaral, Gregory L. Szeto, Oliver Fuchs, Sophia M. Schüssler-Fiorenza Rose, Shvetank Sharma, Uwe Schwartz, Xabier Bengoetxea Bausela, Maciej Szymkiewicz, Vasileios Maroulis, Anton Salykin, Carolina M. Barra, Candice D. Kruth, Nicholas J. Bongio, Vaibhav Mathur, Radmila D Todoric, Udi E. Rubin, Apostolos Malatras, Carl T. Fulp, John A. Galindo, Ruta Motiejunaite, Christoph Jüschke, Philip C. Dishuck, Katharina Lahl, Mohieddin Jafari, Sara Aibar, Apostolos Zaravinos, Linda H. Steenhuizen, Lindsey R. Allison, Pablo Gamallo, Fernando de Andres Segura, Tyler Dae Devlin, Vicente Pérez-García, Avi Ma’ayan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
A wealth of gene expression data is publicly available, yet is little use without additional human curation. Ma’ayan and colleagues report a crowdsourcing project involving over 70 participants to annotate and analyse thousands of human disease-rel
Externí odkaz:
https://doaj.org/article/a8f2b28d890e4a0e99fc75b9634da8c0
Autor:
Jonathan H. Chen, Linda T. Nieman, Maxwell Spurrell, Vjola Jorgji, Peter Richieri, Katherine H. Xu, Roopa Madhu, Milan Parikh, Izabella Zamora, Arnav Mehta, Christopher S. Nabel, Samuel S. Freeman, Joshua D. Pirl, Chenyue Lu, Catherine B. Meador, Jaimie L. Barth, Mustafa Sakhi, Alexander L. Tang, Siranush Sarkizova, Colles Price, Nicolas F. Fernandez, George Emanuel, Jiang He, Katrina Van Raay, Jason W. Reeves, Keren Yizhak, Matan Hofree, Angela Shih, Moshe Sade-Feldman, Genevieve M. Boland, Karin Pelka, Martin Aryee, Ilya Korsunsky, Mari Mino-Kenudson, Justin F. Gainor, Nir Hacohen
Publikováno v:
bioRxiv
The organization of immune cells in human tumors is not well understood. Immunogenic tumors harbor spatially-localized multicellular ‘immunity hubs’ defined by expression of the T cell-attracting chemokinesCXCL10/CXCL11and abundant T cells. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34a8311fe1a0ffaf6c8bf19497a54e4
https://europepmc.org/articles/PMC10104028/
https://europepmc.org/articles/PMC10104028/
Autor:
Avi Ma'ayan, Nahid Turan, Bradley L. Demarest, Brent W. Bisgrove, Richard P. Lifton, Zichen Wang, Christine E. Seidman, Alessandro Giardini, Alexander Lachmann, Wendy K. Chung, Richard B. Kim, George A. Porter, Amy E. Roberts, Bruce D. Gelb, Andrew D. Rouillard, Martin Tristani-Firouzi, Sunita S. Shankaran, Deepak Srivastava, Nicolas F. Fernandez, Jonathan J. Edwards, Jane W. Newburger, Martina Brueckner, Elizabeth Goldmuntz, Daniel Bernstein, John E. Deanfield, H. Joseph Yost
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • Combining CHD phenotype–driven gene set enrichment and CRISPR knockdown screening in zebrafish is an effective approach to identifying novel CHD genes. • Mutations affecting genes coding for the WAVE2 protein c
Highlights • Combining CHD phenotype–driven gene set enrichment and CRISPR knockdown screening in zebrafish is an effective approach to identifying novel CHD genes. • Mutations affecting genes coding for the WAVE2 protein c
Autor:
Letizia Amadori, Claudia Calcagno, Dawn M Fernandez, Simon Koplev, Nicolas F Fernandez, Ravneet Kaur, Roza Shamailova, Peik Sean Chong, Swathy Sajja, Sonum Naidu, Adam Ghotbi, Raphael Soler, Christopher Hill, Zahi A Fayad, Avi Ma'ayan, Chiara Giannarelli
Publikováno v:
Circulation. 144
Introduction: Inflammation is a key driver of atherosclerosis. The identification of new treatments and strategies targeting the specific inflammatory signaling that persists in optimally treated atherosclerotic patients remain an unmet clinical need
Autor:
Emily R. Stern, James W. Murrough, Alexis E. Whitton, Seunghee Kim-Schulze, Laurel S. Morris, Katherine A. Collins, Michael K. Parides, Abigail B Collins, Nicolas F. Fernandez, Manishkumar Patel, Sara Costi, Hui Xie, Diego A. Pizzagalli, Flurin Cathomas, Scott J. Russo
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Increased levels of peripheral cytokines have been previously associated with depression in preclinical and clinical research. Although the precise nature of peripheral immune dysfunction in depression remains unclear, evidence from animal studies po
Autor:
Li Ding, Shaji Kumar, Beena E Thomas, Shaadi Mehr, David Avigan, Mark Hamilton, Ravi Vij, Daniel Auclair, Hearn Jay Cho, Sacha Gnjatic, Swati S Bhasin, Nicolas F. Fernandez, Manoj Bhasin, Reyka G Jayasinghe, Madhav V. Dhodapkar, Taxiarchis Kourelis
Publikováno v:
Blood. 136:6-8
Introduction: Multiple myeloma (MM) is a genetically complex and clinically heterogeneous disease. Disease biology and phenotype is heavily influenced by the tumor microenvironment and the interaction between the immune milieu and malignant plasma ce
Autor:
Ephraim Kenigsberg, Joan Shang, Jovani Catalan, Tamar Plitt, Dan Fu Ruan, Katherine E. Lindblad, Jamie Redes, Francesca Cossarini, Zeynep H. Gümüş, Maria Casanova-Acebes, Julio A. Aguirre-Ghiso, Nina Bhardwaj, Robert M. Samstein, Venu Pothula, Uri Laserson, Matthew Lin, Erica Dalla, Jeremiah J. Faith, Manasi Agrawal, Alice O. Kamphorst, Ivan Reyes Torres, Luisanna Pia, Monica Centa, Jessica Tan, Brian D. Brown, Jonathan Chung, Graham J. Britton, Miriam Saffern, Assaf Magen, Matthew P. Spindler, Conor Gruber, Saurabh Mehandru, Amir Horowitz, Timothy O'Donnell, Florian Krammer, Jill Gregory, Gabrielle Lubitz, Pauline Hamon, Meriem Belabed, Matthew Brown, Emma Risson, Louise Malle, Emilie K. Grasset, Alfonso R. Sanchez-Paulete, Justine Noel, Zafar Mahmood, Daniel Lozano-Ojalvo, Mark P. Roberto, Julia Kodysh, Verena van der Heide, Evan Cody, Elliot Meritt, Chang Moon, Maria Suprun, Andrew Leader, Bérengère Salomé, Nicolas F. Fernandez, Dusan Bogunovic, Michelle Tran, Nicolas Vabret, Dirk Homann, Miyo Ota, Cansu Cimen Bozkus, Andrew Charap, Divya Jha, Konstantina Alexandropoulos, Etienne Humblin, Benjamin Greenbaum, Maria Kuksin, Gustavo Martinez-Delgado, Andrew K Chan, Myvizhi Esai Selvan, C. Matthias Wilk, Maria A. Curotto de Lafaille, Samarth Hegde, Alessandra Soares Schanoski, Joel Kim, Jaime Mateus-Tique, Alvaro Moreira, John A. Grout, Rachel Levantovsky, Natalie Vaninov, Peter S. Heeger, Mark Aleynick, Matthew D. Park, Judy H. Cho, Miriam Merad, Steven T. Chen
Publikováno v:
Immunity
The coronavirus disease 2019 (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting an unprecedented effort from the scientific community to understand the biolo
Autor:
Seunghee Kim-Schulze, J. Mocco, Miriam Merad, Dawn Fernandez, Chiara Giannarelli, Christopher Hill, Roza Shamailova, Adeeb Rahman, Nicolas F. Fernandez, Peter L. Faries
Publikováno v:
JVS-Vascular Science, Vol 1, Iss, Pp 250-(2020)
Autor:
Katherine Svensson, Alison P. Sanders, Gleicy M. Hair, Paul Curtin, Robert O. Wright, Seunghee Kim-Schulze, Ivan Pantic, Martha María Téllez-Rojo, Marcela Tamayo-Ortiz, Yuri Levin-Schwartz, Daniel Flores, Nicolas F. Fernandez, María Luisa Pizano-Zárate, Andrea A. Baccarelli, Lisa M. Satlin, Chris Gennings
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 12, p e0227219 (2019)
PLoS ONE, Vol 14, Iss 12, p e0227219 (2019)
Infants born prematurely or with low birth weights are more susceptible to kidney dysfunction throughout their lives. Multiple proteins measured in urine are noninvasive biomarkers of subclinical kidney damage, but few studies have examined the joint