Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Nicolas Coudevylle"'
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 161-164 (2022)
Externí odkaz:
https://doaj.org/article/e3b6119c5e1e46689e0054c9850deec8
Publikováno v:
Journal of Magnetic Resonance Open, Vol 12, Iss , Pp 100078- (2022)
Externí odkaz:
https://doaj.org/article/8e1a01e43461440fb6a1fa236c2845a0
Autor:
Valerie Mertens, Marie Jose Abi Saad, Nicolas Coudevylle, Marielle Aulikki Wälti, Aaron Finke, May Marsh, Julien Orts
Publikováno v:
Journal of Magnetic Resonance Open, Vol 10, Iss , Pp 100032- (2022)
Protein—ligand complex structures are key in structure-based drug discovery, but their derivation largely relies on X-ray crystallography. While NMR is able to provide atomic resolution complex structures, traditional NMR structure calculation meth
Externí odkaz:
https://doaj.org/article/c4581ebbe1304cc48792e0f992daca3e
Autor:
Martin Graef, Verena Baumann, Gerhard Hummer, Veronika Nogellova, Christine Abert, Nicolas Coudevylle, Justyna Sawa-Makarska, Martina Schuschnig, Sascha Martens, Sören von Bülow
Publikováno v:
Science
Reconstituting autophagosome nucleation To stay healthy, our cells must constantly dispose of harmful material. Autophagy, or self-eating, is an important mechanism to ensure the clearance of bulky material. Such material is enwrapped by cellular mem
Autor:
Kristina Djinović-Carugo, Isabella Moll, Hannes Temmel, Nicolas Coudevylle, Konstantin Byrgazov, Stefan Arenz, Daniel N. Wilson, Irina Grishkovskaya
Publikováno v:
'Nucleic Acids Research ', vol: 43, pages: 661-673 (2015)
Nucleic Acids Research
Nucleic Acids Research
In Gram-negative bacteria, the multi-domain protein S1 is essential for translation initiation, as it recruits the mRNA and facilitates its localization in the decoding centre. In sharp contrast to its functional importance, S1 is still lacking from
Publikováno v:
ChemBioChem. 14:818-821
You can have one without the other: A new metabolic precursor compound can selectively introduce (13)C and (2)H patterns at leucine residues in proteins in cell-based expression systems without interfering with valine metabolism. The protocol provide
Autor:
Christian Griesinger, Valerie S. Honndorf, Michael Habeck, Nicolas Coudevylle, Stefan Laufer, Stefan Becker
Publikováno v:
Angewandte Chemie-International Edition
Complex problem: The crystal structure of p38α mitogen-activated protein kinase in complex with a dibenzo[a,d]cycloheptenone inhibitor was found to be incompatible with NMR data of the same complex in solution. By using inferential structure determi
Autor:
Nicolas Coudevylle, Olaf Jahn, Stefan Becker, Kalina Dimova, Mitcheell Maestre-Martínez, Harald J. Junge, Nils Brose, Noa Lipstein, Fernando Rodriguez-Castañeda, Christian Griesinger, Donghan Lee, Teresa Carlomagno
Publikováno v:
The EMBO Journal
Ca(2+) signalling in neurons through calmodulin (CaM) has a prominent function in regulating synaptic vesicle trafficking, transport, and fusion. Importantly, Ca(2+)-CaM binds a conserved region in the priming proteins Munc13-1 and ubMunc13-2 and thu
Publikováno v:
Advances in experimental medicine and biology. 870
Intrinsically disordered proteins (IDPs) are characterized by substantial conformational flexibility and thus not amenable to conventional structural biology techniques. Given their inherent structural flexibility NMR spectroscopy offers unique oppor
Autor:
Ana-Isabel, Cabedo Martinez, Katharina, Weinhäupl, Wing-Kee, Lee, Natascha A, Wolff, Barbara, Storch, Szymon, Żerko, Robert, Konrat, Wiktor, Koźmiński, Kathrin, Breuker, Frank, Thévenod, Nicolas, Coudevylle
Publikováno v:
The Journal of Biological Chemistry
The neutrophil gelatinase-associated lipocalin (NGAL, also known as LCN2) and its cellular receptor (LCN2-R, SLC22A17) are involved in many physiological and pathological processes such as cell differentiation, apoptosis, and inflammation. These plei