Zobrazeno 1 - 10
of 343
pro vyhledávání: '"Nicolas CHARLES"'
Autor:
Pavlos Krassakis, Andreas Karavias, Evangelia Zygouri, Nikolaos Koukouzas, Kamil Szewerda, Dariusz Michalak, Tadeja Jegrišnik, Matjaž Kamenik, Nicolas Charles, Laurent Beccaletto, Gaël Bellenfant, Robert Hildebrandt, Sylwia Jarosławska-Sobór, Hernan Flores, Tansel Dogan, Julia Haske, Theodoros Zarogiannis, Ioanna Badouna, Eleonora Manoukian, Eleftheria Karampetsou, Dimitrios Karapanos, Georgios-Orion Marias, George S. Maraslidis, Rania Karametou, Efstratios Giouvanidis
Publikováno v:
Mining, Vol 4, Iss 3, Pp 489-509 (2024)
Heritage and culture tourism involve features that commemorate a valued past. Mining heritage tourism allows visitors to experience the past, guided by former mining landscapes and engaging interactively with material artifacts. This paper introduces
Externí odkaz:
https://doaj.org/article/cf0ef4383da6442dbcba6a00a216ab49
Autor:
John TCHEN, Quentin SIMON, Léa CHAPART, Morgane K. THAMINY, Shamila VIBHUSHAN, Loredana SAVEANU, Yasmine LAMRI, Fanny SAIDOUNE, Emeline PACREAU, Christophe PELLEFIGUES, Julie BEX-COUDRAT, Hajime KARASUYAMA, Kensuke MIYAKE, Juan HIDALGO, Padraic G. FALLON, Thomas PAPO, Ulrich BLANK, Marc BENHAMOU, Guillaume HANOUNA, Karim SACRE, Eric DAUGAS, Nicolas CHARLES
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by anti-nuclear autoantibodies whose production is promoted by autoreactive T follicular helper (TFH) cells. During SLE pathogenesis, basophils accumulate in secondary
Externí odkaz:
https://doaj.org/article/2b261c12033c4401a2b53ad4f143bfa7
Autor:
Karine Baumstarck, Noémie Jourde-Chiche, Eric Daugas, Marie Himbert, Léa Chapart, Nicolas Charles
Publikováno v:
RMD Open, Vol 10, Iss 2 (2024)
Objectives Discontinuation or continuation of maintenance immunosuppressive therapy (MIST) after a severe lupus nephritis (LN) requires measuring the risk of relapse but reliable clinical and biological markers are lacking. The WIN-IgE study assesses
Externí odkaz:
https://doaj.org/article/598e7182dc5241c8adcccaba4546241a
Autor:
John Tchen, Quentin Simon, Léa Chapart, Christophe Pellefigues, Hajime Karasuyama, Kensuke Miyake, Ulrich Blank, Marc Benhamou, Eric Daugas, Nicolas Charles
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tissue-specific mouse models are essential tools to decipher the role of each cell compartment and/or their expressed genes in the pathophysiology of diseases. Here, we describe a new knock-in mouse model allowing expression of both the fluorescent p
Externí odkaz:
https://doaj.org/article/6d84a6fd725646d891b31d23a059b29f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Systemic lupus erythematosus is a complex autoimmune disease during which patients develop autoantibodies raised against nuclear antigens. During the course of the disease, by accumulating in secondary lymphoid organs (SLOs), basophils support autore
Externí odkaz:
https://doaj.org/article/385df604c19b4f3489d0325aa240165e
Autor:
Christophe Pellefigues, Barbara Dema, Yasmine Lamri, Fanny Saidoune, Nathalie Chavarot, Charlotte Lohéac, Emeline Pacreau, Michael Dussiot, Caroline Bidault, Florian Marquet, Mathieu Jablonski, Jonathan M. Chemouny, Fanny Jouan, Antoine Dossier, Marie-Paule Chauveheid, Delphine Gobert, Thomas Papo, Hajime Karasuyama, Karim Sacré, Eric Daugas, Nicolas Charles
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
In a lupus environment, basophils accumulate in secondary lymphoid organs where they affect pathogenesis by stimulating autoantibody production. Here the authors show this accumulation is driven by PGD2-induced CXCR4 surface expression and traffickin
Externí odkaz:
https://doaj.org/article/80954cdc9d4244429cf721f1490b4ce5
Autor:
Barbara Dema, Yasmine Lamri, Christophe Pellefigues, Emeline Pacreau, Fanny Saidoune, Caroline Bidault, Hajime Karasuyama, Karim Sacré, Eric Daugas, Nicolas Charles
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Lupus nephritis (LN), one of the most severe outcomes of systemic lupus erythematosus (SLE), is initiated by glomerular deposition of immune-complexes leading to an inflammatory response and kidney failure. Autoantibodies to nuclear antigens
Externí odkaz:
https://doaj.org/article/d1e831bfa8914cf4b9b64614988ae423
Autor:
Sanae Ben Mkaddem, Amaya Murua, Héloise Flament, Dimitri Titeca-Beauport, Carine Bounaix, Luca Danelli, Pierre Launay, Marc Benhamou, Ulrich Blank, Eric Daugas, Nicolas Charles, Renato C. Monteiro
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Src-family kinases Fyn and Lyn are signaling components downstream of ITAM-bearing antigen receptors. Here the authors show that by phosphorylating SHP-1 at different residues, Lyn and Fyn can have opposing regulatory effects on ITAM receptors.
Externí odkaz:
https://doaj.org/article/018c8dd96b534ef981f995c3443a4374
Autor:
Yasmine Lamri, Nicolas Charles
Publikováno v:
Antibodies, Vol 9, Iss 4, p 69 (2020)
Systemic lupus erythematosus (SLE) is a multifactorial chronic autoimmune disease, marked by the presence of autoantibodies to nuclear antigens belonging to different isotype classes. For several years, IgE antibodies have been incriminated in the de
Externí odkaz:
https://doaj.org/article/35ed1f1748d94153a8fb70d962e6104b
Autor:
Shamila Vibhushan, Manuela Bratti, Juan Eduardo Montero-Hernández, Alaa El Ghoneimi, Marc Benhamou, Nicolas Charles, Eric Daugas, Ulrich Blank
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1, p 302 (2020)
A sizable part (~2%) of the human genome encodes for proteases. They are involved in many physiological processes, such as development, reproduction and inflammation, but also play a role in pathology. Mast cells (MC) contain a variety of MC specific
Externí odkaz:
https://doaj.org/article/2a3ec03afd2d4b499c916061d5bc3657