Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Nicolas C, Hoch"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/c2d931f63c5a4627ac2c87ede38df66e
Autor:
Gabrielle J. Grundy, Luis M. Polo, Zhihong Zeng, Stuart L. Rulten, Nicolas C. Hoch, Pathompong Paomephan, Yingqi Xu, Steve M. Sweet, Alan W. Thorne, Antony W. Oliver, Steve J. Matthews, Laurence H. Pearl, Keith W. Caldecott
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Chromosomal single-strand DNA breaks occur frequently and require repair to avoid disease outcomes. Here, the authors show that in bird cells, PARP3 accelerates this repair, and use structural biology and cell biology techniques to reveal details of
Externí odkaz:
https://doaj.org/article/f4adc148d44f418d9df058242e7f3bd6
Autor:
Henrietta Papp, Judit Bóvári-Biri, Krisztina Bánfai, Péter Juhász, Mohamed Mahdi, Lilian Cristina Russo, Dávid Bajusz, Adrienn Sipos, László Petri, Ágnes Kemény, Mónika Madai, Anett Kuczmog, Gyula Batta, Orsolya Mózner, Dorottya Vaskó, Edit Hirsch, Péter Bohus, Gábor Méhes, József Tőzsér, Nicola J. Curtin, Zsuzsanna Helyes, Attila Tóth, Nicolas C. Hoch, Ferenc Jakab, György M. Keserű, Judit E. Pongrácz, Péter Bai
Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2 virus, is a major global health challenge, as there is no efficient treatment for the moderate to severe disease. ADP-ribosylation events are involved in regulating the life cycle of coronavir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::145b8e760a029eba2091d7fe2df24c06
https://doi.org/10.1101/2022.06.30.22277079
https://doi.org/10.1101/2022.06.30.22277079
Autor:
Ricardo Di Lazzaro Filho, Guilherme Lopes Yamamoto, Tiago J Silva, Leticia A Rocha, Bianca D W Linnenkamp, Matheus Augusto Araújo Castro, Deborah Bartholdi, André Schaller, Tosso Leeb, Samantha Kelmann, Claudia Y Utagawa, Carlos E Steiner, Leandra Steinmetz, Rachel Sayuri Honjo, Chong Ae Kim, Lisa Wang, Raphaël Abourjaili-Bilodeau, Philippe M Campeau, Matthew Warman, Maria Rita Passos-Bueno, Nicolas C Hoch, Debora Romeo Bertola
Publikováno v:
Journal of Medical Genetics. :jmg-2022
Rothmund-Thomson syndrome (RTS) is a rare, heterogeneous autosomal recessive genodermatosis, with poikiloderma as its hallmark. It is classified into two types: type I, with biallelic variants inANAPC1and juvenile cataracts, and type II, with biallel
Autor:
Flavia Carla Meotti, Isaac Araújo Matos, Alexandre Bruni-Cardoso, Sven T. Sowa, Nicolas C. Hoch, Lillian Cristina Russo, Keith W. Caldecott, Deborah Schechtman, Katie L. Dale, Antonio Carlos Manucci, Lari Lehtiö, Rebeka Tomasin
SARS-CoV-2 non-structural protein 3 (Nsp3) contains a macrodomain that is essential for virus replication and is thus an attractive target for drug development. This macrodomain is thought to counteract the host interferon (IFN) response, an importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca012b6b7170ce0cd5c7e3e76cfd2859
https://doi.org/10.1101/2021.04.06.438552
https://doi.org/10.1101/2021.04.06.438552
Autor:
Lari Lehtiö, Deborah Schechtman, Lilian C. Russo, Flavia Carla Meotti, Alexandre Bruni-Cardoso, Sven T. Sowa, Katie Dale, Nicolas C. Hoch, Rebeka Tomasin, Isaac Araújo Matos, Antonio Carlos Manucci, Keith W. Caldecott
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
The Journal of Biological Chemistry
Universidade de São Paulo (USP)
instacron:USP
The Journal of Biological Chemistry
SARS-CoV-2 non-structural protein 3 (Nsp3) contains a macrodomain that is essential for coronavirus pathogenesis and is thus an attractive target for drug development. This macrodomain is thought to counteract the host interferon (IFN) response, an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a396bc7a41b47b6893e98087d73781
Autor:
Aswin Mangerich, Karla L. H. Feijs, Bernhard Lüscher, José Yélamos, Matthias Altmeyer, Bryce M. Paschal, Xiaochun Yu, Roko Zaja, Alan Ashworth, Zhao-Qi Wang, Mathias Ziegler, Nicolas C. Hoch, Susan Smith, Valina L. Dawson, George Lucian Moldovan, Guy G. Poirier, Anthony K.L. Leung, Sebastian Guettler, Christopher J. Lord, Daniela Corda, Giovanna Grimaldi, Andreas G. Ladurner, Jason Matthews, Ivan Matic, Françoise Dantzer, W. Lee Kraus, Dmitri V. Filippov, Péter Bai, Jean-Philippe Gagné, Michael O. Hottiger, John M. Pascal, Sebastian Deindl, Michael S. Cohen, Patricia Korn, Anthony R. Fehr, Mario Niepel, Joel Moss, Michael L. Nielsen, Matthew D. Daugherty, Friedrich Nolte, Krzysztof Pawłowski, Gyula Timinszky, Gioacchino Natoli, Lari Lehtiö, Ivan Ahel, Ted M. Dawson, Paul Chang
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
FEBS J
FEBS Journal
FEBS Journal, Wiley, 2021, ⟨10.1111/febs.16142⟩
The FEBS journal, vol 289, iss 23
FEBS Journal. WILEY
The FEBS Journal
Lüscher, B, Ahel, I, Altmeyer, M, Ashworth, A, Bai, P, Chang, P, Cohen, M, Corda, D, Dantzer, F, Daugherty, M D, Dawson, T M, Dawson, V L, Deindl, S, Fehr, A R, Feijs, K L H, Filippov, D V, Gagné, J P, Grimaldi, G, Guettler, S, Hoch, N C, Hottiger, M O, Korn, P, Kraus, W L, Ladurner, A, Lehtiö, L, Leung, A K L, Lord, C J, Mangerich, A, Matic, I, Matthews, J, Moldovan, G L, Moss, J, Natoli, G, Nielsen, M L, Niepel, M, Nolte, F, Pascal, J, Paschal, B M, Pawłowski, K, Poirier, G G, Smith, S, Timinszky, G, Wang, Z Q, Yélamos, J, Yu, X, Zaja, R & Ziegler, M 2022, ' ADP-ribosyltransferases, an update on function and nomenclature ', FEBS Journal, vol. 289, no. 23, pp. 7399-7410 . https://doi.org/10.1111/febs.16142
Universidade de São Paulo (USP)
instacron:USP
FEBS J
FEBS Journal
FEBS Journal, Wiley, 2021, ⟨10.1111/febs.16142⟩
The FEBS journal, vol 289, iss 23
FEBS Journal. WILEY
The FEBS Journal
Lüscher, B, Ahel, I, Altmeyer, M, Ashworth, A, Bai, P, Chang, P, Cohen, M, Corda, D, Dantzer, F, Daugherty, M D, Dawson, T M, Dawson, V L, Deindl, S, Fehr, A R, Feijs, K L H, Filippov, D V, Gagné, J P, Grimaldi, G, Guettler, S, Hoch, N C, Hottiger, M O, Korn, P, Kraus, W L, Ladurner, A, Lehtiö, L, Leung, A K L, Lord, C J, Mangerich, A, Matic, I, Matthews, J, Moldovan, G L, Moss, J, Natoli, G, Nielsen, M L, Niepel, M, Nolte, F, Pascal, J, Paschal, B M, Pawłowski, K, Poirier, G G, Smith, S, Timinszky, G, Wang, Z Q, Yélamos, J, Yu, X, Zaja, R & Ziegler, M 2022, ' ADP-ribosyltransferases, an update on function and nomenclature ', FEBS Journal, vol. 289, no. 23, pp. 7399-7410 . https://doi.org/10.1111/febs.16142
ADP-ribosylation, a modification of proteins, nucleic acids and metabolites, confers broad functions, including roles in stress responses elicited for example by DNA damage and viral infection and is involved in intra- and extracellular signaling, ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630b65b016239f43979422dfa49f94cd
Autor:
Rui Liu, Jörg Heierhorst, Nicolas C. Hoch, Ashleigh King, Gemma L. Kelly, Catherine Chang, Andrew J. Deans
Publikováno v:
DNA Repair
Highlights • ASCIZ/ATMIN is not required for ATM activation by replication stress in MEFs. • ATM activation is normal in human ASCIZ/ATMIN KO cells. • ASCIZ/ATMIN is dispensable for aphidicolin-induced 53BP1 focus formation.
The ATM kinase
The ATM kinase
Autor:
Alicia J. Kowaltowski, Fabio Luis Forti, Roberto Kopke Salinas, S C Farah, Nicolas C. Hoch, Ricardo J. Giordano, Ohara Augusto, Glaucia Mendes Souza, A. M. Da-Silva, P. Di Mascio, Cypreste Oliveira, Walter R. Terra, Sayuri Miyamoto, Claudiana Lameu, M. J. M. Alves, Daniela S. Basseres, Alexandre Bruni-Cardoso, Sandro R. Marana, Hugo A. Armelin, Hernan Chaimovich, João C. Setubal, Deborah Schechtman, Marisa Helena Gennari de Medeiros, Sergio Verjovski-Almeida, Eduardo M. Reis, Maria Teresa Machini, Suely Lopes Gomes, Shirley Schreier, F J Gueiros Filho, Henning Ulrich, Bettina Malnic, Walter Colli, Mari Cleide Sogayar, P. Colepicolo Neto, Carlos Takeshi Hotta, Graziella E. Ronsein, Mauricio S. Baptista, Iolanda M. Cuccovia, Daniela R. Truzzi, Leticia Labriola, Flavia Vischi Winck, Carmen Veríssima Ferreira, Guilherme Menegon Arantes, Flavia Carla Meotti, Bianca Zingales, Regina L. Baldini, Nadja C. de Souza-Pinto, Etelvino J. H. Bechara
Publikováno v:
Brazilian Journal of Medical and Biological Research
Brazilian Journal of Medical and Biological Research, Volume: 52, Issue: 9, Article number: e8935, Published: 29 AUG 2019
Brazilian Journal of Medical and Biological Research, Vol 52, Iss 9
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Medical and Biological Research, Volume: 52, Issue: 9, Article number: e8935, Published: 29 AUG 2019
Brazilian Journal of Medical and Biological Research, Vol 52, Iss 9
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
The scientific publication landscape is changing quickly, with an enormous increase in options and models. Articles can be published in a complex variety of journals that differ in their presentation format (online-only or in-print), editorial organi
Autor:
Ashleigh King, Nicolas C. Hoch, Ian M. Smyth, Natalie A. Sims, Narelle E. McGregor, Jörg Heierhorst
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Mutations in subunits of the cilia-specific cytoplasmic dynein-2 (CD2) complex cause short-rib thoracic dystrophy syndromes (SRTDs), characterized by impaired bone growth and life-threatening perinatal respiratory complications. Different SRTD mutati